STRINGSTRING
PLIN5 PLIN5 AKT2 AKT2 PDK4 PDK4 TYSND1 TYSND1 SOX9 SOX9 AKT1 AKT1 APPL2 APPL2 ACADVL ACADVL ACACB ACACB SIRT4 SIRT4 SMIM37 SMIM37 ETFBKMT ETFBKMT ABCB11 ABCB11 ABCD1 ABCD1 IRS2 IRS2 ABCD2 ABCD2 LONP2 LONP2 FMO4 FMO4 FMO1 FMO1 IRS1 IRS1 FMO3 FMO3 FMO2 FMO2 LOC112396202 LOC112396202 MFSD2A MFSD2A TWIST1 TWIST1 PPARA PPARA MLYCD MLYCD LOC112392089 LOC112392089
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLIN5Perilipin; Belongs to the perilipin family. (457 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PDK4Protein-serine/threonine kinase. (407 aa)
TYSND1Peroxisomal leader peptide-processing protease isoform X1. (568 aa)
SOX9Transcription factor SOX-9. (486 aa)
AKT1RAC-alpha serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (339 aa)
APPL2DCC-interacting protein 13-beta isoform X1. (661 aa)
ACADVLVery long-chain specific acyl-CoA dehydrogenase, mitochondrial isoform X1. (655 aa)
ACACBacetyl-CoA carboxylase 2. (2456 aa)
SIRT4NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (314 aa)
SMIM37LOW QUALITY PROTEIN: small integral membrane protein 37. (113 aa)
ETFBKMTElectron transfer flavoprotein beta subunit lysine methyltransferase. (266 aa)
ABCB11Bile salt export pump isoform X1. (1326 aa)
ABCD1ATP-binding cassette sub-family D member 1 isoform X1. (774 aa)
IRS2Insulin receptor substrate 2. (702 aa)
ABCD2ATP-binding cassette sub-family D member 2 isoform X1. (741 aa)
LONP2Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. (852 aa)
FMO4Dimethylaniline monooxygenase [N-oxide-forming]. (577 aa)
FMO1Dimethylaniline monooxygenase [N-oxide-forming]. (539 aa)
IRS1Insulin receptor substrate 1. (1248 aa)
FMO3Flavin-containing monooxygenase. (281 aa)
FMO2Dimethylaniline monooxygenase [N-oxide-forming]. (537 aa)
LOC112396202Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa)
MFSD2ASodium-dependent lysophosphatidylcholine symporter 1 isoform X1. (529 aa)
TWIST1LOW QUALITY PROTEIN: twist-related protein 1. (152 aa)
PPARAPeroxisome proliferator-activated receptor alpha. (468 aa)
MLYCDmalonyl-CoA decarboxylase, mitochondrial. (498 aa)
LOC112392089RAC-alpha serine/threonine-protein kinase. (138 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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