(33 nodes) Positive regulation of glucose import network (Neophocaena asiaeorientalis)

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second shell of interactors

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experimentally determined

Predicted Interactions

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protein homology

Your Input:
	GPC3	Glypican-3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (580 aa)
	APPL1	DCC-interacting protein 13-alpha isoform X1. (708 aa)
	INSR	Tyrosine-protein kinase receptor. (1382 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
	OPN3	LOW QUALITY PROTEIN: opsin-3; Belongs to the G-protein coupled receptor 1 family. (521 aa)
	IRS1	Insulin receptor substrate 1. (1248 aa)
	OSBPL8	Oxysterol-binding protein; Belongs to the OSBP family. (889 aa)
	POU4F2	POU domain protein. (408 aa)
	LOC112392549	Prorelaxin. (183 aa)
	PRKCI	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (597 aa)
	NFE2L2	Nuclear factor erythroid 2-related factor 2 isoform X1. (622 aa)
	LOC112392089	RAC-alpha serine/threonine-protein kinase. (138 aa)
	MEF2A	Myocyte-specific enhancer factor 2A isoform X1. (501 aa)
	TERT	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1136 aa)
	RNASEL	2-5A-dependent ribonuclease isoform X1. (736 aa)
	IGF1	Insulin-like growth factor I isoform X1. (208 aa)
	CREBL2	cAMP-responsive element-binding protein-like 2 isoform X1. (132 aa)
	AKT2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
	FGF21	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	ADIPOQ	Adiponectin. (243 aa)
	CAPN10	Calpain-10 isoform X1; Belongs to the peptidase C2 family. (848 aa)
	C1QTNF12	Adipolin. (267 aa)
	ITLN1	LOW QUALITY PROTEIN: intelectin-1. (206 aa)
	AKT1	RAC-alpha serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (339 aa)
	PTH	Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (119 aa)
	OCLN	Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (520 aa)
	IRS2	Insulin receptor substrate 2. (702 aa)
	RHOQ	Rho-related GTP-binding protein RhoQ isoform X1. (280 aa)
	PIK3R1	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
	ERFE	Erythroferrone. (273 aa)
	SLC1A2	Amino acid transporter. (574 aa)
	FGF19	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (363 aa)
	INS	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)

Your Current Organism:

Neophocaena asiaeorientalis

NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADIPOQ	APPL1	A0A341DAP3	A0A341BJ25	Adiponectin.	DCC-interacting protein 13-alpha isoform X1.	0.539
ADIPOQ	FGF21	A0A341DAP3	A0A341DBA5	Adiponectin.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.669
ADIPOQ	IGF1	A0A341DAP3	A0A341ADG7	Adiponectin.	Insulin-like growth factor I isoform X1.	0.544
ADIPOQ	INS	A0A341DAP3	A0A341BTK8	Adiponectin.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.819
ADIPOQ	INSR	A0A341DAP3	A0A341BIP5	Adiponectin.	Tyrosine-protein kinase receptor.	0.459
ADIPOQ	IRS1	A0A341DAP3	A0A341B0M9	Adiponectin.	Insulin receptor substrate 1.	0.624
ADIPOQ	IRS2	A0A341DAP3	A0A341C791	Adiponectin.	Insulin receptor substrate 2.	0.472
AKT1	APPL1	A0A341CGU0	A0A341BJ25	RAC-alpha serine/threonine-protein kinase; Belongs to the protein kinase superfamily.	DCC-interacting protein 13-alpha isoform X1.	0.869
AKT1	IGF1	A0A341CGU0	A0A341ADG7	RAC-alpha serine/threonine-protein kinase; Belongs to the protein kinase superfamily.	Insulin-like growth factor I isoform X1.	0.477
AKT1	INS	A0A341CGU0	A0A341BTK8	RAC-alpha serine/threonine-protein kinase; Belongs to the protein kinase superfamily.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.576
AKT1	IRS1	A0A341CGU0	A0A341B0M9	RAC-alpha serine/threonine-protein kinase; Belongs to the protein kinase superfamily.	Insulin receptor substrate 1.	0.543
AKT1	IRS2	A0A341CGU0	A0A341C791	RAC-alpha serine/threonine-protein kinase; Belongs to the protein kinase superfamily.	Insulin receptor substrate 2.	0.431
AKT1	LOC112392089	A0A341CGU0	A0A341AFJ6	RAC-alpha serine/threonine-protein kinase; Belongs to the protein kinase superfamily.	RAC-alpha serine/threonine-protein kinase.	0.846
AKT1	NFE2L2	A0A341CGU0	A0A341AHP2	RAC-alpha serine/threonine-protein kinase; Belongs to the protein kinase superfamily.	Nuclear factor erythroid 2-related factor 2 isoform X1.	0.690
AKT1	PIK3R1	A0A341CGU0	A0A341C200	RAC-alpha serine/threonine-protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.876
AKT2	APPL1	A0A341DDW1	A0A341BJ25	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	DCC-interacting protein 13-alpha isoform X1.	0.869
AKT2	IGF1	A0A341DDW1	A0A341ADG7	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Insulin-like growth factor I isoform X1.	0.477
AKT2	INS	A0A341DDW1	A0A341BTK8	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.576
AKT2	IRS1	A0A341DDW1	A0A341B0M9	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Insulin receptor substrate 1.	0.543
AKT2	IRS2	A0A341DDW1	A0A341C791	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Insulin receptor substrate 2.	0.431