STRINGSTRING
NGFR NGFR CDK6 CDK6 TGFB1 TGFB1 LIF LIF ESR1 ESR1 HRAS HRAS CD248 CD248 DDR2 DDR2 GAS6 GAS6 LIG4 LIG4 EREG EREG AQP1 AQP1 FNDC3B FNDC3B JUN JUN WNT2 WNT2 SPHK1 SPHK1 ITGB3 ITGB3 PDGFB PDGFB PML PML WNT5A WNT5A FN1 FN1 PDGFA PDGFA LOC112412159 LOC112412159 FOSL2 FOSL2 BRK1 BRK1 LOC112413803 LOC112413803 CDKN1A CDKN1A CTC1 CTC1 WAPL WAPL DHX9 DHX9 IGF1 IGF1 CD74 CD74 LOC112393429 LOC112393429 WNT1 WNT1 ZMIZ1 ZMIZ1 NDUFS4 NDUFS4 FGF10 FGF10 PLA2G1B PLA2G1B MYC MYC E2F1 E2F1 FBRS FBRS PDGFRA PDGFRA PDGFC PDGFC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NGFRTumor necrosis factor receptor superfamily member 16. (427 aa)
CDK6Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
LIFLeukemia inhibitory factor. (202 aa)
ESR1Estrogen receptor. (604 aa)
HRASGTPase HRas isoform X1. (189 aa)
CD248Endosialin. (754 aa)
DDR2Discoidin domain-containing receptor 2. (820 aa)
GAS6Growth arrest-specific protein 6. (540 aa)
LIG4DNA ligase. (911 aa)
EREGProepiregulin. (163 aa)
AQP1Aquaporin-1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
FNDC3BFibronectin type III domain-containing protein 3B isoform X1. (1147 aa)
JUNLOW QUALITY PROTEIN: transcription factor AP-1; Belongs to the bZIP family. (284 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
SPHK1Sphingosine kinase 1. (391 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (789 aa)
PDGFBPlatelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (209 aa)
PMLProtein PML isoform X1. (965 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
FN1Fibronectin isoform X5. (2478 aa)
PDGFAPlatelet-derived growth factor subunit A isoform X1; Belongs to the PDGF/VEGF growth factor family. (211 aa)
LOC112412159Uncharacterized protein LOC112412159. (208 aa)
FOSL2Fos-related antigen 2 isoform X1. (327 aa)
BRK1Protein BRICK1. (75 aa)
LOC112413803Polycomb complex protein BMI-1. (326 aa)
CDKN1ACyclin-dependent kinase inhibitor 1. (164 aa)
CTC1CST complex subunit CTC1 isoform X1. (1208 aa)
WAPLWings apart-like protein homolog isoform X1. (1196 aa)
DHX9ATP-dependent RNA helicase A isoform X1. (1253 aa)
IGF1Insulin-like growth factor I isoform X1. (208 aa)
CD74HLA class II histocompatibility antigen gamma chain isoform X1. (278 aa)
LOC112393429Probable protein BRICK1. (58 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
ZMIZ1Zinc finger MIZ domain-containing protein 1. (1065 aa)
NDUFS4NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial. (175 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
PLA2G1BPhospholipase A(2). (160 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa)
E2F1Transcription factor E2F1. (360 aa)
FBRSProbable fibrosin-1. (1010 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
PDGFCPlatelet-derived growth factor C isoform X1. (314 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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