STRINGSTRING
EPB41L5 EPB41L5 BMP4 BMP4 FOXF1 FOXF1 NKX2-3 NKX2-3 RBPMS2 RBPMS2 ID2 ID2 SHH SHH SHOX2 SHOX2 FGF10 FGF10 SOX17 SOX17 PDGFRA PDGFRA WNT5A WNT5A HIF1A HIF1A HLX HLX SIX2 SIX2 CTNNB1 CTNNB1 NIPBL NIPBL BCL2 BCL2 LOC112407979 LOC112407979 WNT11 WNT11 LOC112407988 LOC112407988 AHI1 AHI1 TCF21 TCF21 SOX10 SOX10 STRA6 STRA6 NOTCH1 NOTCH1 IHH IHH SFRP1 SFRP1 NODAL NODAL AGR2 AGR2 TP63 TP63 EPHB3 EPHB3 GLI3 GLI3 SMAD3 SMAD3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EPB41L5Band 4.1-like protein 5 isoform X1. (746 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (420 aa)
FOXF1Forkhead box protein F1. (375 aa)
NKX2-3Homeobox protein Nkx-2.3. (363 aa)
RBPMS2LOW QUALITY PROTEIN: RNA-binding protein with multiple splicing 2. (279 aa)
ID2DNA-binding protein inhibitor ID-2. (134 aa)
SHHSonic hedgehog protein. (328 aa)
SHOX2Short stature homeobox protein 2 isoform X1. (333 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
SOX17LOW QUALITY PROTEIN: transcription factor SOX-17. (207 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
HIF1AHypoxia-inducible factor 1-alpha. (823 aa)
HLXH2.0-like homeobox protein. (486 aa)
SIX2Homeobox protein SIX2 isoform X1. (298 aa)
CTNNB1Catenin beta-1. (781 aa)
NIPBLNipped-B protein. (2803 aa)
BCL2Apoptosis regulator Bcl-2 isoform X1. (233 aa)
LOC112407979Secreted frizzled-related protein 2-like. (105 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
LOC112407988Secreted frizzled-related protein 2. (294 aa)
AHI1Jouberin isoform X1. (1178 aa)
TCF21Transcription factor 21. (179 aa)
SOX10Transcription factor SOX-10. (468 aa)
STRA6Receptor for retinol uptake STRA6. (668 aa)
NOTCH1LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 1. (2633 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
SFRP1Secreted frizzled-related protein 1. (296 aa)
NODALNodal homolog. (348 aa)
AGR2Anterior gradient protein 2 homolog. (175 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
EPHB3Ephrin type-B receptor 3. (959 aa)
GLI3Transcriptional activator GLI3. (1587 aa)
SMAD3Mothers against decapentaplegic homolog. (376 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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