STRINGSTRING
SHOX2 SHOX2 NDST1 NDST1 DLX2 DLX2 HOXD10 HOXD10 MMP16 MMP16 HOXD4 HOXD4 CHST11 CHST11 WDR19 WDR19 TULP3 TULP3 HOXD3 HOXD3 HOXD1 HOXD1 SP3 SP3 DLX1 DLX1 HOXD9 HOXD9 GLI3 GLI3 FGF8 FGF8 SMAD3 SMAD3 DMRT2 DMRT2 TGFBR1 TGFBR1 BMP4 BMP4 EDNRA EDNRA HOXC6 HOXC6 HOXC11 HOXC11 HOXC9 HOXC9 MYF5 MYF5 LOC112394195 LOC112394195 HOXC4 HOXC4 COL2A1 COL2A1 TWIST1 TWIST1 SHH SHH PCSK5 PCSK5 EYA1 EYA1 SULF1 SULF1 SLC39A3 SLC39A3 EXT1 EXT1 MMP14 MMP14 ALX3 ALX3 TAPT1 TAPT1 NKX3-2 NKX3-2 HOXB6 HOXB6 HOXB8 HOXB8 HOXB2 HOXB2 PRRX1 PRRX1 HOXB5 HOXB5 TBXT TBXT PCGF2 PCGF2 COL1A1 COL1A1 HOXB4 HOXB4 HOXB1 HOXB1 HOXB9 HOXB9 PDGFRA PDGFRA SLC2A10 SLC2A10 HOXB7 HOXB7 WNT5A WNT5A TFAP2A TFAP2A OSR1 OSR1 SULF2 SULF2 MTHFD1L MTHFD1L SIX1 SIX1 IRX5 IRX5 SLC39A1 SLC39A1 SIX4 SIX4 ALX4 ALX4 ZEB1 ZEB1 FLVCR1 FLVCR1 BMP7 BMP7 HAND2 HAND2 SETD2 SETD2 DLG1 DLG1 DSCAML1 DSCAML1 SIX2 SIX2 WDR60 WDR60 FGF9 FGF9 CTNNB1 CTNNB1 NIPBL NIPBL HOXA5 HOXA5 HOXA9 HOXA9 HOXA6 HOXA6 HOXA3 HOXA3 HOXA11 HOXA11 HOXA7 HOXA7 HOXA2 HOXA2 FGFR2 FGFR2 GRHL2 GRHL2 OSR2 OSR2 WNT11 WNT11 NOG NOG MKS1 MKS1 LHX1 LHX1 SATB2 SATB2 MED12 MED12 IFT140 IFT140 GSC GSC WNT9B WNT9B EIF4A3 EIF4A3 PAX5 PAX5 IHH IHH DLG2 DLG2 TBX15 TBX15 RDH10 RDH10 RUNX2 RUNX2 KIAA1217 KIAA1217 LOC112413803 LOC112413803 UCMA UCMA MDFI MDFI NODAL NODAL FUZ FUZ MEGF8 MEGF8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SHOX2Short stature homeobox protein 2 isoform X1. (333 aa)
NDST1Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1. (883 aa)
DLX2Homeobox protein DLX-2. (387 aa)
HOXD10Homeobox protein Hox-D10. (410 aa)
MMP16Matrix metalloproteinase-16. (607 aa)
HOXD4Homeobox protein Hox-D4. (270 aa)
CHST11Carbohydrate sulfotransferase. (418 aa)
WDR19WD repeat-containing protein 19 isoform X1. (1342 aa)
TULP3Tubby-like protein; Belongs to the TUB family. (464 aa)
HOXD3Homeobox protein Hox-D3 isoform X2. (432 aa)
HOXD1Homeobox protein Hox-D1. (326 aa)
SP3Transcription factor Sp3. (1112 aa)
DLX1Homeobox protein DLX-1 isoform X1. (255 aa)
HOXD9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (282 aa)
GLI3Transcriptional activator GLI3. (1587 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
SMAD3Mothers against decapentaplegic homolog. (376 aa)
DMRT2Doublesex- and mab-3-related transcription factor 2. (561 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (438 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (420 aa)
EDNRAEndothelin-1 receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (427 aa)
HOXC6Homeobox protein Hox-C6 isoform X1. (243 aa)
HOXC11LOW QUALITY PROTEIN: homeobox protein Hox-C11. (308 aa)
HOXC9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (260 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
LOC112394195ALX homeobox protein 1. (326 aa)
HOXC4Homeobox protein Hox-C4. (264 aa)
COL2A1Collagen alpha-1(II) chain. (1487 aa)
TWIST1LOW QUALITY PROTEIN: twist-related protein 1. (152 aa)
SHHSonic hedgehog protein. (328 aa)
PCSK5Proprotein convertase subtilisin/kexin type 5 isoform X2; Belongs to the peptidase S8 family. (1877 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (589 aa)
SULF1Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (882 aa)
SLC39A3Zinc transporter ZIP3. (314 aa)
EXT1Exostosin-1; Belongs to the glycosyltransferase 47 family. (746 aa)
MMP14Matrix metalloproteinase-14. (582 aa)
ALX3Homeobox protein aristaless-like 3. (343 aa)
TAPT1Transmembrane anterior posterior transformation protein 1 homolog isoform X1. (462 aa)
NKX3-2Homeobox protein Nkx-3.2. (327 aa)
HOXB6Homeobox protein Hox-B6 isoform X1. (314 aa)
HOXB8Homeobox protein Hox-B8 isoform X1. (243 aa)
HOXB2Homeobox protein Hox-B2. (354 aa)
PRRX1Paired mesoderm homeobox protein 1. (245 aa)
HOXB5Homeobox protein Hox-B5. (269 aa)
TBXTBrachyury protein isoform X1. (435 aa)
PCGF2Polycomb group RING finger protein 2 isoform X1. (389 aa)
COL1A1Collagen alpha-1(I) chain. (1463 aa)
HOXB4LOW QUALITY PROTEIN: homeobox protein Hox-B4. (282 aa)
HOXB1Homeobox protein Hox-B1. (298 aa)
HOXB9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (256 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
SLC2A10Solute carrier family 2, facilitated glucose transporter member 10 isoform X1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (572 aa)
HOXB7Homeobox protein Hox-B7. (217 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
TFAP2ATranscription factor AP-2-alpha isoform X1. (496 aa)
OSR1LOW QUALITY PROTEIN: protein odd-skipped-related 1. (326 aa)
SULF2Extracellular sulfatase Sulf-2. (865 aa)
MTHFD1LMonofunctional C1-tetrahydrofolate synthase, mitochondrial isoform X1. (867 aa)
SIX1Homeobox protein SIX1. (284 aa)
IRX5Iroquois-class homeodomain protein IRX-5. (483 aa)
SLC39A1Zinc transporter ZIP1. (324 aa)
SIX4Homeobox protein SIX4. (793 aa)
ALX4Homeobox protein aristaless-like 4. (408 aa)
ZEB1LOW QUALITY PROTEIN: zinc finger E-box-binding homeobox 1. (1042 aa)
FLVCR1Feline leukemia virus subgroup C receptor-related protein 1 isoform X1. (555 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
HAND2Heart- and neural crest derivatives-expressed protein 2. (208 aa)
SETD2Histone-lysine N-methyltransferase SETD2 isoform X1. (2547 aa)
DLG1Disks large homolog 1 isoform X1; Belongs to the MAGUK family. (927 aa)
DSCAML1Down syndrome cell adhesion molecule-like protein 1. (2121 aa)
SIX2Homeobox protein SIX2 isoform X1. (298 aa)
WDR60WD repeat-containing protein 60 isoform X1. (1057 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
CTNNB1Catenin beta-1. (781 aa)
NIPBLNipped-B protein. (2803 aa)
HOXA5Homeobox protein Hox-A5. (381 aa)
HOXA9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (272 aa)
HOXA6Homeobox protein Hox-A6. (233 aa)
HOXA3LOW QUALITY PROTEIN: homeobox protein Hox-A3. (405 aa)
HOXA11Homeobox protein Hox-A11. (318 aa)
HOXA7Homeobox protein Hox-A7. (233 aa)
HOXA2Homeobox protein Hox-A2. (409 aa)
FGFR2Fibroblast growth factor receptor. (841 aa)
GRHL2Grainyhead-like protein 2 homolog isoform X1. (625 aa)
OSR2Protein odd-skipped-related 2 isoform X1. (312 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
MKS1Meckel syndrome type 1 protein isoform X2. (607 aa)
LHX1LIM/homeobox protein Lhx1. (406 aa)
SATB2DNA-binding protein SATB. (733 aa)
MED12Mediator of RNA polymerase II transcription subunit 12. (2097 aa)
IFT140Intraflagellar transport protein 140 homolog isoform X1. (1489 aa)
GSCHomeobox protein goosecoid. (256 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (602 aa)
EIF4A3Eukaryotic initiation factor 4A-III; Belongs to the DEAD box helicase family. (411 aa)
PAX5Paired box protein Pax-5 isoform X1. (391 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
DLG2Disks large homolog 2 isoform X1. (905 aa)
TBX15T-box transcription factor TBX15. (602 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
RUNX2Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (408 aa)
KIAA1217Sickle tail protein homolog isoform X1. (1947 aa)
LOC112413803Polycomb complex protein BMI-1. (326 aa)
UCMAUnique cartilage matrix-associated protein. (138 aa)
MDFImyoD family inhibitor isoform X1. (245 aa)
NODALNodal homolog. (348 aa)
FUZProtein fuzzy homolog isoform X1. (440 aa)
MEGF8Multiple epidermal growth factor-like domains protein 8. (2784 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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