STRINGSTRING
NOTCH4 NOTCH4 TGFB3 TGFB3 ZMPSTE24 ZMPSTE24 IL6 IL6 SHH SHH TGFB2 TGFB2 PCSK9 PCSK9 DDR1 DDR1 STK11 STK11 ANXA1 ANXA1 ISL1 ISL1 CITED2 CITED2 NRG3 NRG3 FGF10 FGF10 EXT1 EXT1 PRL PRL BSX BSX LEF1 LEF1 SCRIB SCRIB CSF1 CSF1 CSN2 CSN2 CSN3 CSN3 RB1CC1 RB1CC1 TBX3 TBX3 PLAG1 PLAG1 HNF1A HNF1A MED1 MED1 EZH2 EZH2 MSX1 MSX1 UBE3A UBE3A EGF EGF BRAF BRAF MAFB MAFB GHRH GHRH SRC SRC PAX8 PAX8 BCL2L11 BCL2L11 NR0B1 NR0B1 MAN2A1 MAN2A1 ASXL1 ASXL1 TGM2 TGM2 STAT5A STAT5A ARMC5 ARMC5 MAPK3 MAPK3 LOC112399174 LOC112399174 FGF2 FGF2 HOXB9 HOXB9 PDGFRA PDGFRA ACER1 ACER1 CDK5RAP3 CDK5RAP3 HOXB13 HOXB13 PRKCSH PRKCSH HESX1 HESX1 RXFP1 RXFP1 WNT5A WNT5A FEM1B FEM1B SALL1 SALL1 GCM2 GCM2 NKX3-1 NKX3-1 HNF4A HNF4A SULF2 SULF2 ADA ADA LATS1 LATS1 ZBTB7B ZBTB7B PYGO2 PYGO2 SIX1 SIX1 CTC1 CTC1 RPGRIP1L RPGRIP1L IQGAP3 IQGAP3 ESR1 ESR1 GDF7 GDF7 SIX4 SIX4 FGF7 FGF7 ASH1L ASH1L HIF1A HIF1A NTN1 NTN1 ELK1 ELK1 KDM5B KDM5B LRP5 LRP5 CCND1 CCND1 SELENOH SELENOH RELA RELA ELF3 ELF3 LAMA5 LAMA5 FADD FADD HLX HLX ZBTB1 ZBTB1 IRF6 IRF6 EPHA2 EPHA2 CEBPB CEBPB PCK1 PCK1 PAX1 PAX1 BMP7 BMP7 HAND2 HAND2 CADM1 CADM1 PROX1 PROX1 LOC112403992 LOC112403992 APOA1 APOA1 AR AR MKI67 MKI67 WT1 WT1 MSN MSN PITX1 PITX1 HGF HGF HES1 HES1 NKX2-5 NKX2-5 PAX6 PAX6 PCK2 PCK2 PTCH1 PTCH1 RIPK3 RIPK3 DRD2 DRD2 CTNNB1 CTNNB1 AREG AREG SOCS2 SOCS2 ONECUT1 ONECUT1 TNFRSF11A TNFRSF11A IRS2 IRS2 SERPINB5 SERPINB5 HOXA5 HOXA5 HOXA9 HOXA9 ONECUT2 ONECUT2 BCL2 BCL2 HOXA3 HOXA3 TNFSF11 TNFSF11 PDX1 PDX1 GHRHR GHRHR PIK3CA PIK3CA SEC63 SEC63 JUN JUN EDA EDA TGFA TGFA PLXND1 PLXND1 RAF1 RAF1 DKK3 DKK3 PTCD2 PTCD2 TAF10 TAF10 SLC46A2 SLC46A2 EAF2 EAF2 CSMD1 CSMD1 XBP1 XBP1 EPHB3 EPHB3 CCDC39 CCDC39 TP63 TP63 ARHGAP35 ARHGAP35 TGFB1 TGFB1 RHBDD3 RHBDD3 CLCN2 CLCN2 SOSTDC1 SOSTDC1 ATM ATM FRZB FRZB NODAL NODAL CSMD2 CSMD2 LRRC1 LRRC1 SRF SRF GPAT4 GPAT4 POLB POLB WNT3A WNT3A ZNF703 ZNF703 ARID5B ARID5B BMP2 BMP2 SFRP1 SFRP1 WDR77 WDR77 IGSF3 IGSF3 NOTCH2 NOTCH2 SMARCB1 SMARCB1 E2F8 E2F8 COBL COBL EDN1 EDN1 PLXNA1 PLXNA1 JARID2 JARID2 CRKL CRKL SERPINE2 SERPINE2 CUL3 CUL3 TWSG1 TWSG1 MAD1L1 MAD1L1 MAPK1 MAPK1 LAMA1 LAMA1 TNC TNC WNT10A WNT10A ERBB4 ERBB4 NOTCH1 NOTCH1 NR5A1 NR5A1 SMO SMO ABL1 ABL1 LHX3 LHX3 NKX2-1 NKX2-1 FOXA1 FOXA1 SRP54 SRP54 CCDC40 CCDC40 PML PML NPHP3 NPHP3 CRHR1 CRHR1 STRA6 STRA6 WNT3 WNT3 SLC9A3R1 SLC9A3R1 SOX10 SOX10 ZIC3 ZIC3 FASN FASN SOX9 SOX9 NFIB NFIB ZDHHC21 ZDHHC21 GFER GFER LOC112409981 LOC112409981 FGL1 FGL1 TCF21 TCF21 PKD1 PKD1 POU3F2 POU3F2 ORAI1 ORAI1 LOC112409102 LOC112409102 AIRE AIRE CAV1 CAV1 WNT2 WNT2 PROP1 PROP1 DDX55 DDX55 LOC112408488 LOC112408488 EDAR EDAR BCL11B BCL11B GATA6 GATA6 TBX2 TBX2 NOG NOG WNT11 WNT11 HNF1B HNF1B SMAD4 SMAD4 BMPR1A BMPR1A ALDH1A3 ALDH1A3 GATA3 GATA3 TPH1 TPH1 SLC6A3 SLC6A3 OTP OTP SEMA3C SEMA3C ARF6 ARF6 CDKN1B CDKN1B HOXD13 HOXD13 HOXD3 HOXD3 ASCL1 ASCL1 PHB2 PHB2 LSR LSR CEBPG CEBPG UPF2 UPF2 FOXE1 FOXE1 SP3 SP3 ATF2 ATF2 HOXD9 HOXD9 GLI3 GLI3 NEURL1 NEURL1 USF2 USF2 FGF8 FGF8 LOC112392034 LOC112392034 SMAD3 SMAD3 MAP2K1 MAP2K1 ESRP2 ESRP2 TGFBR1 TGFBR1 BMP4 BMP4 TFCP2L1 TFCP2L1 DNAAF1 DNAAF1 ACADM ACADM FOXF1 FOXF1 ATP2C2 ATP2C2 NFKB1 NFKB1 BTRC BTRC FOXB1 FOXB1 EDNRA EDNRA NKX2-3 NKX2-3 PKD2 PKD2 NF1 NF1 FRS2 FRS2 RARG RARG ZNF330 ZNF330 FA2H FA2H AGAP2 AGAP2 CACNB4 CACNB4 SERPINF1 SERPINF1 VDR VDR STAT6 STAT6 ID2 ID2 GLI1 GLI1 FOXN1 FOXN1 MST1 MST1 E2F7 E2F7 LOC112394306 LOC112394306 CREB1 CREB1 PSEN1 PSEN1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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NOTCH4Neurogenic locus notch homolog protein 4 isoform X1. (1993 aa)
TGFB3Transforming growth factor beta-3. (456 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (473 aa)
IL6Interleukin-6. (208 aa)
SHHSonic hedgehog protein. (328 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
PCSK9Proprotein convertase subtilisin/kexin type 9. (703 aa)
DDR1Tyrosine-protein kinase receptor. (932 aa)
STK11Serine/threonine-protein kinase STK11 isoform X1. (546 aa)
ANXA1Annexin. (346 aa)
ISL1Insulin gene enhancer protein ISL-1. (349 aa)
CITED2Cbp/p300-interacting transactivator 2. (263 aa)
NRG3Pro-neuregulin-3, membrane-bound isoform isoform X3. (613 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
EXT1Exostosin-1; Belongs to the glycosyltransferase 47 family. (746 aa)
PRLProlactin isoform X1. (230 aa)
BSXBrain-specific homeobox protein homolog. (232 aa)
LEF1Lymphoid enhancer-binding factor 1 isoform X1. (414 aa)
SCRIBLOW QUALITY PROTEIN: protein scribble homolog. (1575 aa)
CSF1Macrophage colony-stimulating factor 1. (513 aa)
CSN2Beta-casein; Important role in determination of the surface properties of the casein micelles. (224 aa)
CSN3Kappa-casein; Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk; Belongs to the kappa-casein family. (189 aa)
RB1CC1RB1-inducible coiled-coil protein 1 isoform X1. (1658 aa)
TBX3LOW QUALITY PROTEIN: T-box transcription factor TBX3. (734 aa)
PLAG1Zinc finger protein PLAG1 isoform X1. (499 aa)
HNF1AHepatocyte nuclear factor 1-alpha isoform X1. (632 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1579 aa)
EZH2Histone-lysine N-methyltransferase EZH2 isoform X1. (751 aa)
MSX1Homeobox protein MSX-1. (303 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (875 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1238 aa)
BRAFSerine/threonine-protein kinase B-raf isoform X1. (581 aa)
MAFBTranscription factor MafB. (323 aa)
GHRHSomatoliberin. (106 aa)
SRCTyrosine-protein kinase. (601 aa)
PAX8Paired box protein Pax-8 isoform X1. (458 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (196 aa)
NR0B1Nuclear receptor subfamily 0 group B member 1. (464 aa)
MAN2A1Alpha-mannosidase. (1145 aa)
ASXL1Putative Polycomb group protein ASXL1. (1517 aa)
TGM2Protein-glutamine gamma-glutamyltransferase 2. (687 aa)
STAT5ASignal transducer and activator of transcription. (726 aa)
ARMC5Armadillo repeat-containing protein 5. (827 aa)
MAPK3Mitogen-activated protein kinase 3. (265 aa)
LOC112399174Signal transducer and activator of transcription. (618 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (304 aa)
HOXB9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (256 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
ACER1Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (264 aa)
CDK5RAP3CDK5 regulatory subunit-associated protein 3 isoform X1. (538 aa)
HOXB13Homeobox protein Hox-B13. (285 aa)
PRKCSHGlucosidase 2 subunit beta. (409 aa)
HESX1Homeobox expressed in ES cells 1 isoform X1. (185 aa)
RXFP1Relaxin receptor 1. (653 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
FEM1BProtein fem-1 homolog B. (627 aa)
SALL1Sal-like protein 1. (1307 aa)
GCM2Chorion-specific transcription factor GCMb. (551 aa)
NKX3-1Homeobox protein Nkx-3.1. (241 aa)
HNF4AHepatocyte nuclear factor 4-alpha isoform X1. (484 aa)
SULF2Extracellular sulfatase Sulf-2. (865 aa)
ADAAdenosine deaminase isoform X1. (402 aa)
LATS1Serine/threonine-protein kinase LATS1. (1128 aa)
ZBTB7BZinc finger and BTB domain-containing protein 7B. (542 aa)
PYGO2Pygopus homolog 2. (406 aa)
SIX1Homeobox protein SIX1. (284 aa)
CTC1CST complex subunit CTC1 isoform X1. (1208 aa)
RPGRIP1LProtein fantom. (1269 aa)
IQGAP3Ras GTPase-activating-like protein IQGAP3. (1633 aa)
ESR1Estrogen receptor. (604 aa)
GDF7Growth/differentiation factor 7. (381 aa)
SIX4Homeobox protein SIX4. (793 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
ASH1LHistone-lysine N-methyltransferase ASH1L. (2964 aa)
HIF1AHypoxia-inducible factor 1-alpha. (823 aa)
NTN1Netrin-1. (604 aa)
ELK1ETS domain-containing protein Elk-1 isoform X1. (442 aa)
KDM5BLysine-specific demethylase 5B. (1311 aa)
LRP5Low-density lipoprotein receptor-related protein 5 isoform X1. (1461 aa)
CCND1G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa)
SELENOHSelenoprotein H. (122 aa)
RELATranscription factor p65. (562 aa)
ELF3ETS-related transcription factor Elf-3. (372 aa)
LAMA5LOW QUALITY PROTEIN: laminin subunit alpha-5. (3401 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (211 aa)
HLXH2.0-like homeobox protein. (486 aa)
ZBTB1Zinc finger and BTB domain-containing protein 1. (713 aa)
IRF6Interferon regulatory factor 6 isoform X1. (467 aa)
EPHA2Ephrin type-A receptor 2. (975 aa)
CEBPBCCAAT/enhancer-binding protein. (346 aa)
PCK1Phosphoenolpyruvate carboxykinase, cytosolic [GTP]. (622 aa)
PAX1LOW QUALITY PROTEIN: paired box protein Pax-1. (445 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
HAND2Heart- and neural crest derivatives-expressed protein 2. (208 aa)
CADM1Cell adhesion molecule 1 isoform X1. (470 aa)
PROX1Prospero homeobox protein 1 isoform X1. (737 aa)
LOC112403992Nucleoside diphosphate kinase. (152 aa)
APOA1Apolipoprotein A-I. (265 aa)
ARAndrogen receptor isoform X1. (893 aa)
MKI67Proliferation marker protein Ki-67. (2619 aa)
WT1Wilms tumor protein isoform X1. (450 aa)
MSNMoesin isoform X1. (579 aa)
PITX1Homeobox protein. (435 aa)
HGFHepatocyte growth factor isoform X1; Belongs to the peptidase S1 family. (734 aa)
HES1Transcription factor HES-1. (280 aa)
NKX2-5Homeobox protein Nkx-2.5. (323 aa)
PAX6Paired box protein Pax-6 isoform X1. (493 aa)
PCK2Phosphoenolpyruvate carboxykinase [GTP], mitochondrial isoform X1. (650 aa)
PTCH1Protein patched homolog 1 isoform X1. (1297 aa)
RIPK3LOW QUALITY PROTEIN: receptor-interacting serine/threonine-protein kinase 3. (518 aa)
DRD2D(2) dopamine receptor isoform X2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
CTNNB1Catenin beta-1. (781 aa)
AREGAmphiregulin isoform X1. (253 aa)
SOCS2Suppressor of cytokine signaling 2. (198 aa)
ONECUT1One cut domain family member. (465 aa)
TNFRSF11ATumor necrosis factor receptor superfamily member 11A. (689 aa)
IRS2Insulin receptor substrate 2. (702 aa)
SERPINB5Serpin B5; Belongs to the serpin family. (375 aa)
HOXA5Homeobox protein Hox-A5. (381 aa)
HOXA9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (272 aa)
ONECUT2One cut domain family member. (367 aa)
BCL2Apoptosis regulator Bcl-2 isoform X1. (233 aa)
HOXA3LOW QUALITY PROTEIN: homeobox protein Hox-A3. (405 aa)
TNFSF11Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family. (323 aa)
PDX1Pancreas/duodenum homeobox protein 1. (289 aa)
GHRHRGrowth hormone-releasing hormone receptor isoform X1; Belongs to the G-protein coupled receptor 2 family. (456 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
SEC63Translocation protein SEC63 homolog. (760 aa)
JUNLOW QUALITY PROTEIN: transcription factor AP-1; Belongs to the bZIP family. (284 aa)
EDAectodysplasin-A; Belongs to the tumor necrosis factor family. (259 aa)
TGFAProtransforming growth factor alpha isoform X1. (290 aa)
PLXND1plexin-D1. (1847 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa)
DKK3Dickkopf-related protein 3. (349 aa)
PTCD2LOW QUALITY PROTEIN: pentatricopeptide repeat-containing protein 2, mitochondrial. (384 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (152 aa)
SLC46A2Thymic stromal cotransporter homolog. (469 aa)
EAF2ELL-associated factor 2. (264 aa)
CSMD1CUB and sushi domain-containing protein 1. (3778 aa)
XBP1LOW QUALITY PROTEIN: X-box-binding protein 1. (379 aa)
EPHB3Ephrin type-B receptor 3. (959 aa)
CCDC39Coiled-coil domain-containing protein 39. (941 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
ARHGAP35Rho GTPase-activating protein 35. (1500 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
RHBDD3Rhomboid domain-containing protein 3. (386 aa)
CLCN2Chloride channel protein 2. (904 aa)
SOSTDC1Sclerostin domain-containing protein 1. (206 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3064 aa)
FRZBSecreted frizzled-related protein 3. (325 aa)
NODALNodal homolog. (348 aa)
CSMD2CUB and sushi domain-containing protein 2. (3656 aa)
LRRC1Leucine-rich repeat-containing protein 1. (443 aa)
SRFSerum response factor isoform X1. (535 aa)
GPAT4Glycerol-3-phosphate acyltransferase 4. (456 aa)
POLBDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (328 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
ZNF703Zinc finger protein 703. (620 aa)
ARID5BAT-rich interactive domain-containing protein 5B isoform X1. (1184 aa)
BMP2Bone morphogenetic protein 2 isoform X1. (395 aa)
SFRP1Secreted frizzled-related protein 1. (296 aa)
WDR77Methylosome protein 50 isoform X1. (342 aa)
IGSF3Immunoglobulin superfamily member 3. (1191 aa)
NOTCH2Neurogenic locus notch homolog protein 2 isoform X1. (2485 aa)
SMARCB1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (385 aa)
E2F8Transcription factor E2F8. (866 aa)
COBLProtein cordon-bleu isoform X1. (1274 aa)
EDN1Endothelin-1. (202 aa)
PLXNA1LOW QUALITY PROTEIN: plexin-A1. (2367 aa)
JARID2Protein Jumonji isoform X1. (1235 aa)
CRKLCrk-like protein. (303 aa)
SERPINE2Glia-derived nexin; Belongs to the serpin family. (397 aa)
CUL3Cullin-3 isoform X1; Belongs to the cullin family. (746 aa)
TWSG1Twisted gastrulation protein homolog 1. (223 aa)
MAD1L1Mitotic spindle assembly checkpoint protein MAD1 isoform X1. (717 aa)
MAPK1Mitogen-activated protein kinase. (343 aa)
LAMA1Laminin subunit alpha-1. (3081 aa)
TNCTenascin isoform X4. (2201 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
NOTCH1LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 1. (2633 aa)
NR5A1Steroidogenic factor 1. (461 aa)
SMOSmoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (783 aa)
ABL1Tyrosine-protein kinase. (1148 aa)
LHX3LIM/homeobox protein Lhx3. (378 aa)
NKX2-1Homeobox protein Nkx-2.1 isoform X1. (396 aa)
FOXA1Hepatocyte nuclear factor 3-alpha. (466 aa)
SRP54Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (504 aa)
CCDC40Coiled-coil domain-containing protein 40. (1132 aa)
PMLProtein PML isoform X1. (965 aa)
NPHP3Nephrocystin-3 isoform X2. (1234 aa)
CRHR1Corticotropin-releasing factor receptor 1; Belongs to the G-protein coupled receptor 2 family. (480 aa)
STRA6Receptor for retinol uptake STRA6. (668 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (453 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (366 aa)
SOX10Transcription factor SOX-10. (468 aa)
ZIC3Zinc finger protein ZIC 3. (455 aa)
FASNFatty acid synthase. (2520 aa)
SOX9Transcription factor SOX-9. (486 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (570 aa)
ZDHHC21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
GFERSulfhydryl oxidase. (206 aa)
LOC112409981ectodysplasin-A-like. (214 aa)
FGL1Fibrinogen-like protein 1. (315 aa)
TCF21Transcription factor 21. (179 aa)
PKD1Polycystin-1. (4487 aa)
POU3F2POU domain protein. (436 aa)
ORAI1LOW QUALITY PROTEIN: calcium release-activated calcium channel protein 1. (410 aa)
LOC112409102Protein LEG1 homolog. (356 aa)
AIREAutoimmune regulator. (553 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
PROP1Homeobox protein prophet of Pit-1. (226 aa)
DDX55RNA helicase. (600 aa)
LOC112408488Serine/threonine-protein kinase B-raf-like. (250 aa)
EDARTumor necrosis factor receptor superfamily member EDAR isoform X1. (456 aa)
BCL11BB-cell lymphoma/leukemia 11B. (740 aa)
GATA6Transcription factor GATA-6. (448 aa)
TBX2T-box transcription factor TBX2. (588 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
HNF1BHepatocyte nuclear factor 1-beta isoform X1. (558 aa)
SMAD4Mothers against decapentaplegic homolog. (599 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
ALDH1A3Aldehyde dehydrogenase family 1 member A3; Belongs to the aldehyde dehydrogenase family. (512 aa)
GATA3Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (444 aa)
TPH1Tryptophan 5-hydroxylase 1. (455 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (617 aa)
OTPHomeobox protein orthopedia. (325 aa)
SEMA3Csemaphorin-3C; Belongs to the semaphorin family. (751 aa)
ARF6ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
CDKN1BCyclin-dependent kinase inhibitor 1B. (198 aa)
HOXD13Homeobox protein Hox-D13. (264 aa)
HOXD3Homeobox protein Hox-D3 isoform X2. (432 aa)
ASCL1LOW QUALITY PROTEIN: achaete-scute homolog 1. (228 aa)
PHB2Prohibitin. (299 aa)
LSRLipolysis-stimulated lipoprotein receptor isoform X1. (599 aa)
CEBPGCCAAT/enhancer-binding protein gamma. (185 aa)
UPF2Regulator of nonsense transcripts 2 isoform X1. (1270 aa)
FOXE1Forkhead box protein E1. (354 aa)
SP3Transcription factor Sp3. (1112 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa)
HOXD9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (282 aa)
GLI3Transcriptional activator GLI3. (1587 aa)
NEURL1E3 ubiquitin-protein ligase NEURL1 isoform X1. (574 aa)
USF2Upstream stimulatory factor 2. (360 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
LOC112392034Signal transducer and activator of transcription 5A-like. (105 aa)
SMAD3Mothers against decapentaplegic homolog. (376 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
ESRP2Epithelial splicing regulatory protein 2 isoform X1. (767 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (438 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (420 aa)
TFCP2L1Transcription factor CP2-like protein 1 isoform X1. (489 aa)
DNAAF1Dynein assembly factor 1, axonemal. (680 aa)
ACADMMedium-chain specific acyl-CoA dehydrogenase, mitochondrial isoform X1. (421 aa)
FOXF1Forkhead box protein F1. (375 aa)
ATP2C2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (975 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit isoform X1. (977 aa)
BTRCF-box/WD repeat-containing protein 1A isoform X1. (605 aa)
FOXB1Forkhead box protein B1. (325 aa)
EDNRAEndothelin-1 receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (427 aa)
NKX2-3Homeobox protein Nkx-2.3. (363 aa)
PKD2Polycystin-2 isoform X1. (782 aa)
NF1Neurofibromin isoform X1. (2841 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
RARGRetinoic acid receptor gamma isoform X2. (458 aa)
ZNF330Zinc finger protein 330. (320 aa)
FA2HFatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (372 aa)
AGAP2arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 isoform X1. (836 aa)
CACNB4Voltage-dependent L-type calcium channel subunit beta-4 isoform X2. (473 aa)
SERPINF1Pigment epithelium-derived factor; Belongs to the serpin family. (416 aa)
VDRVitamin D3 receptor. (427 aa)
STAT6Signal transducer and activator of transcription. (859 aa)
ID2DNA-binding protein inhibitor ID-2. (134 aa)
GLI1Zinc finger protein GLI1 isoform X1. (1106 aa)
FOXN1Forkhead box protein N1. (645 aa)
MST1LOW QUALITY PROTEIN: hepatocyte growth factor-like protein; Belongs to the peptidase S1 family. (732 aa)
E2F7Transcription factor E2F7. (905 aa)
LOC112394306C-C motif chemokine. (97 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (468 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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