STRINGSTRING
PTCH1 PTCH1 LAMA5 LAMA5 PAK1 PAK1 TBX20 TBX20 CTNNBIP1 CTNNBIP1 EPHA2 EPHA2 CTSZ CTSZ BMP7 BMP7 GZF1 GZF1 DLG1 DLG1 AR AR HS3ST3A1 HS3ST3A1 ADAMTS16 ADAMTS16 WT1 WT1 NFATC4 NFATC4 GBX2 GBX2 COL4A1 COL4A1 NPNT NPNT CTNNB1 CTNNB1 AREG AREG HOXA5 HOXA5 BCL2 BCL2 HOXA11 HOXA11 GDNF GDNF PLXND1 PLXND1 ILK ILK DCHS1 DCHS1 LOC112407979 LOC112407979 SMAD4 SMAD4 MKS1 MKS1 GREB1L GREB1L TBX2 TBX2 LHX1 LHX1 MET MET LOC112407988 LOC112407988 PKD1 PKD1 TCF21 TCF21 YAP1 YAP1 SPRY2 SPRY2 GNA13 GNA13 WNT9B WNT9B SOX9 SOX9 PML PML FOXA1 FOXA1 NKX2-1 NKX2-1 ENG ENG NOTCH1 NOTCH1 NRARP NRARP WNT6 WNT6 IHH IHH LAMA1 LAMA1 EDN1 EDN1 DLG2 DLG2 BMP2 BMP2 RDH10 RDH10 SRF SRF CSMD2 CSMD2 PKHD1 PKHD1 CLIC4 CLIC4 TMEM59L TMEM59L LOC112415314 LOC112415314 TGFB1 TGFB1 LOC112415334 LOC112415334 CSMD1 CSMD1 KRAS KRAS DLL4 DLL4 LOC112391993 LOC112391993 PHB2 PHB2 GLI3 GLI3 FGF8 FGF8 ESRP2 ESRP2 BMP4 BMP4 FOXF1 FOXF1 PPP3R2 PPP3R2 BTRC BTRC PAX2 PAX2 EDNRA EDNRA PKD2 PKD2 VDR VDR WNT1 WNT1 CELSR1 CELSR1 HHIP HHIP TIMELESS TIMELESS GREB1 GREB1 LOC112394306 LOC112394306 SEMA3E SEMA3E GDF2 GDF2 SHH SHH DDR1 DDR1 EYA1 EYA1 DLG5 DLG5 FGF10 FGF10 EXT1 EXT1 LEF1 LEF1 CSF1 CSF1 LOC112397547 LOC112397547 SLIT2 SLIT2 TBX3 TBX3 MMP14 MMP14 MED1 MED1 EGF EGF RBM15 RBM15 SRC SRC PAX8 PAX8 CTSH CTSH CITED1 CITED1 TIE1 TIE1 FGF2 FGF2 SPRY1 SPRY1 STK4 STK4 WNT5A WNT5A GPC3 GPC3 KDR KDR NKX3-1 NKX3-1 SIX1 SIX1 ESR1 ESR1 GDF7 GDF7 PPP1CA PPP1CA KDM5B KDM5B LRP5 LRP5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PTCH1Protein patched homolog 1 isoform X1. (1297 aa)
LAMA5LOW QUALITY PROTEIN: laminin subunit alpha-5. (3401 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
TBX20T-box transcription factor TBX20. (449 aa)
CTNNBIP1Beta-catenin-interacting protein 1. (81 aa)
EPHA2Ephrin type-A receptor 2. (975 aa)
CTSZCathepsin Z; Belongs to the peptidase C1 family. (303 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
GZF1GDNF-inducible zinc finger protein 1. (715 aa)
DLG1Disks large homolog 1 isoform X1; Belongs to the MAGUK family. (927 aa)
ARAndrogen receptor isoform X1. (893 aa)
HS3ST3A1Sulfotransferase; Belongs to the sulfotransferase 1 family. (406 aa)
ADAMTS16A disintegrin and metalloproteinase with thrombospondin motifs 16. (1453 aa)
WT1Wilms tumor protein isoform X1. (450 aa)
NFATC4Nuclear factor of activated T-cells, cytoplasmic 4 isoform X1. (831 aa)
GBX2Homeobox protein GBX-2 isoform X1. (348 aa)
COL4A1Collagen alpha-1(IV) chain. (1730 aa)
NPNTNephronectin isoform X1. (581 aa)
CTNNB1Catenin beta-1. (781 aa)
AREGAmphiregulin isoform X1. (253 aa)
HOXA5Homeobox protein Hox-A5. (381 aa)
BCL2Apoptosis regulator Bcl-2 isoform X1. (233 aa)
HOXA11Homeobox protein Hox-A11. (318 aa)
GDNFGlial cell line-derived neurotrophic factor isoform X1. (211 aa)
PLXND1plexin-D1. (1847 aa)
ILKIntegrin-linked protein kinase isoform X1. (485 aa)
DCHS1Protocadherin-16. (3294 aa)
LOC112407979Secreted frizzled-related protein 2-like. (105 aa)
SMAD4Mothers against decapentaplegic homolog. (599 aa)
MKS1Meckel syndrome type 1 protein isoform X2. (607 aa)
GREB1LLOW QUALITY PROTEIN: GREB1-like protein. (1833 aa)
TBX2T-box transcription factor TBX2. (588 aa)
LHX1LIM/homeobox protein Lhx1. (406 aa)
METHepatocyte growth factor receptor isoform X1. (1382 aa)
LOC112407988Secreted frizzled-related protein 2. (294 aa)
PKD1Polycystin-1. (4487 aa)
TCF21Transcription factor 21. (179 aa)
YAP1Transcriptional coactivator YAP1. (416 aa)
SPRY2Protein sprouty homolog 2. (315 aa)
GNA13Guanine nucleotide-binding protein subunit alpha-13. (282 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (602 aa)
SOX9Transcription factor SOX-9. (486 aa)
PMLProtein PML isoform X1. (965 aa)
FOXA1Hepatocyte nuclear factor 3-alpha. (466 aa)
NKX2-1Homeobox protein Nkx-2.1 isoform X1. (396 aa)
ENGEndoglin. (652 aa)
NOTCH1LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 1. (2633 aa)
NRARPNotch-regulated ankyrin repeat-containing protein. (114 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
LAMA1Laminin subunit alpha-1. (3081 aa)
EDN1Endothelin-1. (202 aa)
DLG2Disks large homolog 2 isoform X1. (905 aa)
BMP2Bone morphogenetic protein 2 isoform X1. (395 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
SRFSerum response factor isoform X1. (535 aa)
CSMD2CUB and sushi domain-containing protein 2. (3656 aa)
PKHD1Fibrocystin isoform X1. (4079 aa)
CLIC4Chloride intracellular channel protein 4 isoform X1. (253 aa)
TMEM59LTransmembrane protein 59-like isoform X1. (350 aa)
LOC112415314Ras-interacting protein 1-like. (129 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
LOC112415334Ras-interacting protein 1. (615 aa)
CSMD1CUB and sushi domain-containing protein 1. (3778 aa)
KRASGTPase KRas isoform X3. (227 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
LOC112391993Sulfotransferase; Belongs to the sulfotransferase 1 family. (86 aa)
PHB2Prohibitin. (299 aa)
GLI3Transcriptional activator GLI3. (1587 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
ESRP2Epithelial splicing regulatory protein 2 isoform X1. (767 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (420 aa)
FOXF1Forkhead box protein F1. (375 aa)
PPP3R2LOW QUALITY PROTEIN: calcineurin subunit B type 2. (229 aa)
BTRCF-box/WD repeat-containing protein 1A isoform X1. (605 aa)
PAX2Paired box protein Pax-2 isoform X1. (521 aa)
EDNRAEndothelin-1 receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (427 aa)
PKD2Polycystin-2 isoform X1. (782 aa)
VDRVitamin D3 receptor. (427 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
CELSR1Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (2288 aa)
HHIPHedgehog-interacting protein. (700 aa)
TIMELESSProtein timeless homolog. (1202 aa)
GREB1Protein GREB1. (1946 aa)
LOC112394306C-C motif chemokine. (97 aa)
SEMA3Esemaphorin-3E; Belongs to the semaphorin family. (715 aa)
GDF2Growth/differentiation factor 2. (431 aa)
SHHSonic hedgehog protein. (328 aa)
DDR1Tyrosine-protein kinase receptor. (932 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (589 aa)
DLG5Disks large homolog 5; Belongs to the MAGUK family. (1921 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
EXT1Exostosin-1; Belongs to the glycosyltransferase 47 family. (746 aa)
LEF1Lymphoid enhancer-binding factor 1 isoform X1. (414 aa)
CSF1Macrophage colony-stimulating factor 1. (513 aa)
LOC112397547Slit homolog 2 protein-like. (162 aa)
SLIT2Slit homolog 2 protein. (1286 aa)
TBX3LOW QUALITY PROTEIN: T-box transcription factor TBX3. (734 aa)
MMP14Matrix metalloproteinase-14. (582 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1579 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1238 aa)
RBM15Putative RNA-binding protein 15. (962 aa)
SRCTyrosine-protein kinase. (601 aa)
PAX8Paired box protein Pax-8 isoform X1. (458 aa)
CTSHPro-cathepsin H; Belongs to the peptidase C1 family. (297 aa)
CITED1Cbp/p300-interacting transactivator 1. (221 aa)
TIE1Tyrosine-protein kinase receptor Tie-1. (1139 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (304 aa)
SPRY1Protein sprouty homolog 1. (319 aa)
STK4Serine/threonine-protein kinase 4 isoform X1. (487 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
GPC3Glypican-3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (580 aa)
KDRVascular endothelial growth factor receptor 2 isoform X4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
NKX3-1Homeobox protein Nkx-3.1. (241 aa)
SIX1Homeobox protein SIX1. (284 aa)
ESR1Estrogen receptor. (604 aa)
GDF7Growth/differentiation factor 7. (381 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
KDM5BLysine-specific demethylase 5B. (1311 aa)
LRP5Low-density lipoprotein receptor-related protein 5 isoform X1. (1461 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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