STRINGSTRING
LOC112399586 LOC112399586 TPH1 TPH1 SEMA3C SEMA3C LRRK1 LRRK1 DLL4 DLL4 F2R F2R MEF2C MEF2C FGF8 FGF8 JAG1 JAG1 NOL3 NOL3 NFKB1 NFKB1 EDNRA EDNRA ACVRL1 ACVRL1 VDR VDR IL23A IL23A ADRB2 ADRB2 BMPR2 BMPR2 TGFB3 TGFB3 NCDN NCDN FGF10 FGF10 EFNA2 EFNA2 EXT1 EXT1 GPR55 GPR55 BSX BSX FLNA FLNA HNF1A HNF1A PTN PTN SRC SRC CHD7 CHD7 IL1A IL1A MITF MITF MMP2 MMP2 PLG PLG TCIRG1 TCIRG1 LTBP3 LTBP3 HIF1A HIF1A LOC112402169 LOC112402169 TIMP1 TIMP1 LRP5 LRP5 ELF3 ELF3 EPHA2 EPHA2 IL7 IL7 CCR2 CCR2 PTH1R PTH1R TRAF6 TRAF6 SPP2 SPP2 EPAS1 EPAS1 CTNNB1 CTNNB1 HOXA3 HOXA3 SNX10 SNX10 TNFSF11 TNFSF11 ATG5 ATG5 THBS4 THBS4 TPP1 TPP1 HTR1B HTR1B WNT16 WNT16 CAV1 CAV1 RSPO3 RSPO3 CBS CBS CCDC154 CCDC154 GJA1 GJA1 NOX4 NOX4 DBH DBH CTSK CTSK IHH IHH CRB1 CRB1 RASSF2 RASSF2 LGR4 LGR4 NOTCH2 NOTCH2 BAK1 BAK1 PTK2B PTK2B TGFB1 TGFB1 LIF LIF AXL AXL P3H4 P3H4 CTHRC1 CTHRC1 TIE1 TIE1 UMOD UMOD RAB3D RAB3D ACP5 ACP5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC112399586Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (399 aa)
TPH1Tryptophan 5-hydroxylase 1. (455 aa)
SEMA3Csemaphorin-3C; Belongs to the semaphorin family. (751 aa)
LRRK1Leucine-rich repeat serine/threonine-protein kinase 1 isoform X1. (2016 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
F2RProteinase-activated receptor 1; Belongs to the G-protein coupled receptor 1 family. (427 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform X4. (483 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1177 aa)
NOL3Nucleolar protein 3. (202 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit isoform X1. (977 aa)
EDNRAEndothelin-1 receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (427 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (515 aa)
VDRVitamin D3 receptor. (427 aa)
IL23AInterleukin-23 subunit alpha. (189 aa)
ADRB2Beta-2 adrenergic receptor isoform X3. (418 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1012 aa)
TGFB3Transforming growth factor beta-3. (456 aa)
NCDNNeurochondrin isoform X1. (729 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
EFNA2ephrin-A2; Belongs to the ephrin family. (454 aa)
EXT1Exostosin-1; Belongs to the glycosyltransferase 47 family. (746 aa)
GPR55G-protein coupled receptor 55 isoform X1; Belongs to the G-protein coupled receptor 1 family. (407 aa)
BSXBrain-specific homeobox protein homolog. (232 aa)
FLNAfilamin-A isoform X1. (2592 aa)
HNF1AHepatocyte nuclear factor 1-alpha isoform X1. (632 aa)
PTNPleiotrophin isoform X1. (168 aa)
SRCTyrosine-protein kinase. (601 aa)
CHD7LOW QUALITY PROTEIN: chromodomain-helicase-DNA-binding protein 7. (3000 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (265 aa)
MITFMicrophthalmia-associated transcription factor isoform X1. (526 aa)
MMP272 kDa type IV collagenase. (661 aa)
PLGPlasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (814 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (589 aa)
LTBP3Latent-transforming growth factor beta-binding protein 3 isoform X1. (1211 aa)
HIF1AHypoxia-inducible factor 1-alpha. (823 aa)
LOC112402169V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (259 aa)
TIMP1Metalloproteinase inhibitor 1. (260 aa)
LRP5Low-density lipoprotein receptor-related protein 5 isoform X1. (1461 aa)
ELF3ETS-related transcription factor Elf-3. (372 aa)
EPHA2Ephrin type-A receptor 2. (975 aa)
IL7Interleukin-7 isoform X1. (226 aa)
CCR2C-C chemokine receptor type 2; Belongs to the G-protein coupled receptor 1 family. (373 aa)
PTH1RParathyroid hormone/parathyroid hormone-related peptide receptor isoform X1; Belongs to the G-protein coupled receptor 2 family. (583 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (570 aa)
SPP2Secreted phosphoprotein 24. (209 aa)
EPAS1Endothelial PAS domain-containing protein 1 isoform X1. (871 aa)
CTNNB1Catenin beta-1. (781 aa)
HOXA3LOW QUALITY PROTEIN: homeobox protein Hox-A3. (405 aa)
SNX10Sorting nexin-10. (201 aa)
TNFSF11Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family. (323 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
THBS4Thrombospondin-4. (961 aa)
TPP1Tripeptidyl-peptidase 1. (572 aa)
HTR1B5-hydroxytryptamine receptor 1B. (399 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
RSPO3R-spondin-3. (275 aa)
CBSCystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (562 aa)
CCDC154LOW QUALITY PROTEIN: coiled-coil domain-containing protein 154. (699 aa)
GJA1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (381 aa)
NOX4NADPH oxidase 4 isoform X1. (530 aa)
DBHDopamine beta-hydroxylase. (610 aa)
CTSKCathepsin K isoform X1; Belongs to the peptidase C1 family. (358 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
CRB1Protein crumbs homolog 1. (1157 aa)
RASSF2Ras association domain-containing protein 2. (326 aa)
LGR4Leucine-rich repeat-containing G-protein coupled receptor 4. (1061 aa)
NOTCH2Neurogenic locus notch homolog protein 2 isoform X1. (2485 aa)
BAK1Bcl-2 homologous antagonist/killer isoform X1. (239 aa)
PTK2BProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
LIFLeukemia inhibitory factor. (202 aa)
AXLTyrosine-protein kinase receptor UFO. (887 aa)
P3H4LOW QUALITY PROTEIN: endoplasmic reticulum protein SC65. (415 aa)
CTHRC1Collagen triple helix repeat-containing protein 1. (244 aa)
TIE1Tyrosine-protein kinase receptor Tie-1. (1139 aa)
UMODUromodulin. (643 aa)
RAB3DRas-related protein Rab-3D. (219 aa)
ACP5Tartrate-resistant acid phosphatase type 5. (349 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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