STRINGSTRING
UMOD UMOD EXT2 EXT2 TMEM79 TMEM79 ACER1 ACER1 LOC112400718 LOC112400718 SCNN1B SCNN1B SCNN1G SCNN1G ELOVL1 ELOVL1 MLLT6 MLLT6 STARD7 STARD7 LOC112398455 LOC112398455 BPIFA1 BPIFA1 TRPV4 TRPV4 LOC112397408 LOC112397408 EXT1 EXT1 LOC112397124 LOC112397124 PLEC PLEC CLDN1 CLDN1 AQP4 AQP4 AQP2 AQP2 GRHL1 GRHL1 WFS1 WFS1 FA2H FA2H SCNN1A SCNN1A LSR LSR ALOX12 ALOX12 TP63 TP63 KDF1 KDF1 GRHL3 GRHL3 SFN SFN TFAP2B TFAP2B SRF SRF TCHHL1 TCHHL1 UGCG UGCG MET MET CFTR CFTR LOC112407189 LOC112407189 ATP6V1B1 ATP6V1B1 AKAP11 AKAP11 AQP1 AQP1 AQP3 AQP3 IL18 IL18 AQP7 AQP7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UMODUromodulin. (643 aa)
EXT2Exostosin-2 isoform X1; Belongs to the glycosyltransferase 47 family. (718 aa)
TMEM79Transmembrane protein 79. (395 aa)
ACER1Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (264 aa)
LOC112400718Hyaluronidase. (781 aa)
SCNN1BAmiloride-sensitive sodium channel subunit beta; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (641 aa)
SCNN1GAmiloride-sensitive sodium channel subunit gamma; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (651 aa)
ELOVL1Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] (279 aa)
MLLT6Protein AF-17 isoform X1. (1084 aa)
STARD7stAR-related lipid transfer protein 7, mitochondrial. (382 aa)
LOC112398455LOW QUALITY PROTEIN: keratin, type I cytoskeletal 16-like; Belongs to the intermediate filament family. (408 aa)
BPIFA1BPI fold-containing family A member 1. (263 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4 isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (881 aa)
LOC112397408LOW QUALITY PROTEIN: transmembrane protease serine 11F-like; Belongs to the peptidase S1 family. (273 aa)
EXT1Exostosin-1; Belongs to the glycosyltransferase 47 family. (746 aa)
LOC112397124Hyaluronan synthase 2. (552 aa)
PLECLOW QUALITY PROTEIN: plectin. (4609 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
AQP4Aquaporin-4 isoform X1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (323 aa)
AQP2Aquaporin-2 isoform X1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
GRHL1Grainyhead-like protein 1 homolog. (747 aa)
WFS1Wolframin. (889 aa)
FA2HFatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (372 aa)
SCNN1AAmiloride-sensitive sodium channel subunit alpha; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (648 aa)
LSRLipolysis-stimulated lipoprotein receptor isoform X1. (599 aa)
ALOX12Arachidonate 12-lipoxygenase, 12S-type. (663 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
KDF1Keratinocyte differentiation factor 1. (398 aa)
GRHL3Grainyhead-like protein 3 homolog. (602 aa)
SFN14-3-3 protein sigma; Belongs to the 14-3-3 family. (248 aa)
TFAP2BTranscription factor AP-2-beta isoform X1. (469 aa)
SRFSerum response factor isoform X1. (535 aa)
TCHHL1LOW QUALITY PROTEIN: trichohyalin-like protein 1. (920 aa)
UGCGCeramide glucosyltransferase. (394 aa)
METHepatocyte growth factor receptor isoform X1. (1382 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1482 aa)
LOC112407189Cytochrome P450 26B1; Belongs to the cytochrome P450 family. (512 aa)
ATP6V1B1Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (513 aa)
AKAP11A-kinase anchor protein 11 isoform X1. (1909 aa)
AQP1Aquaporin-1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
AQP3Aquaporin-3; Belongs to the MIP/aquaporin (TC 1.A.8) family. (292 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
AQP7LOW QUALITY PROTEIN: aquaporin-7; Belongs to the MIP/aquaporin (TC 1.A.8) family. (330 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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