STRINGSTRING
MAMSTR MAMSTR FBXO22 FBXO22 DMPK DMPK GSK3A GSK3A PI16 PI16 SIRT1 SIRT1 MESP1 MESP1 CCDC142 CCDC142 WNT3A WNT3A MAML1 MAML1 BMP2 BMP2 CAMK1 CAMK1 RBM24 RBM24 EDN1 EDN1 GPER1 GPER1 NOTCH1 NOTCH1 CDK9 CDK9 ENG ENG TRIM32 TRIM32 PLPP7 PLPP7 PDGFB PDGFB HDAC5 HDAC5 SETD3 SETD3 FOXO4 FOXO4 SIK1 SIK1 LOC112408405 LOC112408405 FZD7 FZD7 PRDM6 PRDM6 SMAD4 SMAD4 MEGF10 MEGF10 LOC112407189 LOC112407189 LOC112406522 LOC112406522 PDCD4 PDCD4 LOC112406668 LOC112406668 MECP2 MECP2 HDAC4 HDAC4 BCL2 BCL2 ANKRD17 ANKRD17 ZBED6CL ZBED6CL ATP11A ATP11A EREG EREG NLN NLN NKX2-5 NKX2-5 MYOCD MYOCD LOC112404316 LOC112404316 PROX1 PROX1 LOC112403540 LOC112403540 RBM38 RBM38 MYOG MYOG ZEB1 ZEB1 NFATC2 NFATC2 MTOR MTOR ACTN3 ACTN3 IGF2 IGF2 LOC112402078 LOC112402078 LMOD3 LMOD3 KIT KIT OLFM2 OLFM2 DNMT1 DNMT1 DLL1 DLL1 BHLHA15 BHLHA15 TRIM72 TRIM72 SMYD1 SMYD1 MSX1 MSX1 EZH2 EZH2 MMP14 MMP14 TMEM119 TMEM119 NOV NOV CAV3 CAV3 SHOX2 SHOX2 PTBP1 PTBP1 SHH SHH BMP10 BMP10 BMPR2 BMPR2 TARBP2 TARBP2 MYF5 MYF5 SMAD1 SMAD1 MYF6 MYF6 FRS2 FRS2 RBPMS2 RBPMS2 ARRB2 ARRB2 BMP4 BMP4 SUPT6H SUPT6H NFATC3 NFATC3 BHLHE41 BHLHE41 MEF2C MEF2C AKIRIN2 AKIRIN2 SOX6 SOX6 IGF1 IGF1 MYOD1 MYOD1 BMPR1A BMPR1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAMSTRMEF2-activating motif and SAP domain-containing transcriptional regulator isoform X1. (503 aa)
FBXO22F-box only protein 22. (408 aa)
DMPKMyotonin-protein kinase isoform X1. (722 aa)
GSK3AGlycogen synthase kinase-3 alpha. (320 aa)
PI16Peptidase inhibitor 16; Belongs to the CRISP family. (463 aa)
SIRT1NAD-dependent protein deacetylase sirtuin-1 isoform X1. (557 aa)
MESP1Mesoderm posterior protein 1. (265 aa)
CCDC142Coiled-coil domain-containing protein 142. (764 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
MAML1LOW QUALITY PROTEIN: mastermind-like protein 1. (983 aa)
BMP2Bone morphogenetic protein 2 isoform X1. (395 aa)
CAMK1Calcium/calmodulin-dependent protein kinase type 1 isoform X1; Belongs to the protein kinase superfamily. (387 aa)
RBM24RNA-binding protein 24. (236 aa)
EDN1Endothelin-1. (202 aa)
GPER1G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (358 aa)
NOTCH1LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 1. (2633 aa)
CDK9Cyclin-dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa)
ENGEndoglin. (652 aa)
TRIM32E3 ubiquitin-protein ligase TRIM32. (653 aa)
PLPP7Inactive phospholipid phosphatase 7 isoform X1. (285 aa)
PDGFBPlatelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (209 aa)
HDAC5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1112 aa)
SETD3Protein-histidine N-methyltransferase. (601 aa)
FOXO4Forkhead box protein O4. (512 aa)
SIK1Serine/threonine-protein kinase SIK1. (657 aa)
LOC112408405Uncharacterized protein LOC112408405. (251 aa)
FZD7Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
PRDM6Putative histone-lysine N-methyltransferase PRDM6. (591 aa)
SMAD4Mothers against decapentaplegic homolog. (599 aa)
MEGF10Multiple epidermal growth factor-like domains protein 10. (1138 aa)
LOC112407189Cytochrome P450 26B1; Belongs to the cytochrome P450 family. (512 aa)
LOC112406522RNA-binding protein with multiple splicing 2-like. (233 aa)
PDCD4Programmed cell death protein 4 isoform X1. (485 aa)
LOC112406668Serine/threonine-protein kinase Nek5-like isoform X1. (782 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (470 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1071 aa)
BCL2Apoptosis regulator Bcl-2 isoform X1. (233 aa)
ANKRD17Ankyrin repeat domain-containing protein 17 isoform X1. (2559 aa)
ZBED6CLLOW QUALITY PROTEIN: ZBED6 C-terminal-like protein. (327 aa)
ATP11APhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (987 aa)
EREGProepiregulin. (163 aa)
NLNNeurolysin, mitochondrial isoform X1. (704 aa)
NKX2-5Homeobox protein Nkx-2.5. (323 aa)
MYOCDMyocardin isoform X1. (937 aa)
LOC112404316Ankyrin repeat and KH domain-containing protein 1 isoform X1. (2644 aa)
PROX1Prospero homeobox protein 1 isoform X1. (737 aa)
LOC112403540Olfactory receptor. (298 aa)
RBM38RNA-binding protein 38 isoform X1. (173 aa)
MYOGMyogenin. (224 aa)
ZEB1LOW QUALITY PROTEIN: zinc finger E-box-binding homeobox 1. (1042 aa)
NFATC2Nuclear factor of activated T-cells, cytoplasmic 2 isoform X1. (943 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2548 aa)
ACTN3Alpha-actinin-3. (902 aa)
IGF2Insulin-like growth factor II isoform X1. (184 aa)
LOC112402078RNA-binding protein 4 isoform X1. (363 aa)
LMOD3Leiomodin-3. (564 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (976 aa)
OLFM2Noelin-2. (387 aa)
DNMT1DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1641 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (759 aa)
BHLHA15Class A basic helix-loop-helix protein 15. (215 aa)
TRIM72Tripartite motif-containing protein 72. (519 aa)
SMYD1Histone-lysine N-methyltransferase SMYD1 isoform X1. (490 aa)
MSX1Homeobox protein MSX-1. (303 aa)
EZH2Histone-lysine N-methyltransferase EZH2 isoform X1. (751 aa)
MMP14Matrix metalloproteinase-14. (582 aa)
TMEM119Transmembrane protein 119 isoform X1. (363 aa)
NOVProtein NOV homolog. (359 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
SHOX2Short stature homeobox protein 2 isoform X1. (333 aa)
PTBP1Polypyrimidine tract-binding protein 1 isoform X1. (557 aa)
SHHSonic hedgehog protein. (328 aa)
BMP10Bone morphogenetic protein 10. (423 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1012 aa)
TARBP2RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...] (366 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
MYF6Myogenic factor 6. (241 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
RBPMS2LOW QUALITY PROTEIN: RNA-binding protein with multiple splicing 2. (279 aa)
ARRB2Beta-arrestin-2. (409 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (420 aa)
SUPT6HTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1726 aa)
NFATC3Nuclear factor of activated T-cells, cytoplasmic 3 isoform X1. (1073 aa)
BHLHE41Class E basic helix-loop-helix protein 41. (371 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform X4. (483 aa)
AKIRIN2Akirin-2. (201 aa)
SOX6Transcription factor SOX-6 isoform X5. (835 aa)
IGF1Insulin-like growth factor I isoform X1. (208 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
Server load: low (32%) [HD]