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TMEM119 TMEM119 FZD7 FZD7 SMAD4 SMAD4 LOC112407189 LOC112407189 LOC112406668 LOC112406668 HDAC4 HDAC4 BCL2 BCL2 ATP11A ATP11A NLN NLN NKX2-5 NKX2-5 MYOCD MYOCD PROX1 PROX1 RBM38 RBM38 MYOG MYOG MTOR MTOR ACTN3 ACTN3 LMOD3 LMOD3 DLL1 DLL1 BHLHA15 BHLHA15 TRIM72 TRIM72 SMYD1 SMYD1 MSX1 MSX1 EZH2 EZH2 MMP14 MMP14 SIK1 SIK1 NOV NOV CAV3 CAV3 SHOX2 SHOX2 SHH SHH BMP10 BMP10 MYF5 MYF5 MYF6 MYF6 FRS2 FRS2 ARRB2 ARRB2 BMP4 BMP4 BHLHE41 BHLHE41 MEF2C MEF2C SOX6 SOX6 IGF1 IGF1 FBXO22 FBXO22 DMPK DMPK MAMSTR MAMSTR GSK3A GSK3A PI16 PI16 MESP1 MESP1 WNT3A WNT3A MAML1 MAML1 BMP2 BMP2 RBM24 RBM24 EDN1 EDN1 NOTCH1 NOTCH1 TRIM32 TRIM32 PLPP7 PLPP7 HDAC5 HDAC5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TMEM119Transmembrane protein 119 isoform X1. (363 aa)
FZD7Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
SMAD4Mothers against decapentaplegic homolog. (599 aa)
LOC112407189Cytochrome P450 26B1; Belongs to the cytochrome P450 family. (512 aa)
LOC112406668Serine/threonine-protein kinase Nek5-like isoform X1. (782 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1071 aa)
BCL2Apoptosis regulator Bcl-2 isoform X1. (233 aa)
ATP11APhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (987 aa)
NLNNeurolysin, mitochondrial isoform X1. (704 aa)
NKX2-5Homeobox protein Nkx-2.5. (323 aa)
MYOCDMyocardin isoform X1. (937 aa)
PROX1Prospero homeobox protein 1 isoform X1. (737 aa)
RBM38RNA-binding protein 38 isoform X1. (173 aa)
MYOGMyogenin. (224 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2548 aa)
ACTN3Alpha-actinin-3. (902 aa)
LMOD3Leiomodin-3. (564 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (759 aa)
BHLHA15Class A basic helix-loop-helix protein 15. (215 aa)
TRIM72Tripartite motif-containing protein 72. (519 aa)
SMYD1Histone-lysine N-methyltransferase SMYD1 isoform X1. (490 aa)
MSX1Homeobox protein MSX-1. (303 aa)
EZH2Histone-lysine N-methyltransferase EZH2 isoform X1. (751 aa)
MMP14Matrix metalloproteinase-14. (582 aa)
SIK1Serine/threonine-protein kinase SIK1. (657 aa)
NOVProtein NOV homolog. (359 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
SHOX2Short stature homeobox protein 2 isoform X1. (333 aa)
SHHSonic hedgehog protein. (328 aa)
BMP10Bone morphogenetic protein 10. (423 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
MYF6Myogenic factor 6. (241 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
ARRB2Beta-arrestin-2. (409 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (420 aa)
BHLHE41Class E basic helix-loop-helix protein 41. (371 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform X4. (483 aa)
SOX6Transcription factor SOX-6 isoform X5. (835 aa)
IGF1Insulin-like growth factor I isoform X1. (208 aa)
FBXO22F-box only protein 22. (408 aa)
DMPKMyotonin-protein kinase isoform X1. (722 aa)
MAMSTRMEF2-activating motif and SAP domain-containing transcriptional regulator isoform X1. (503 aa)
GSK3AGlycogen synthase kinase-3 alpha. (320 aa)
PI16Peptidase inhibitor 16; Belongs to the CRISP family. (463 aa)
MESP1Mesoderm posterior protein 1. (265 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
MAML1LOW QUALITY PROTEIN: mastermind-like protein 1. (983 aa)
BMP2Bone morphogenetic protein 2 isoform X1. (395 aa)
RBM24RNA-binding protein 24. (236 aa)
EDN1Endothelin-1. (202 aa)
NOTCH1LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 1. (2633 aa)
TRIM32E3 ubiquitin-protein ligase TRIM32. (653 aa)
PLPP7Inactive phospholipid phosphatase 7 isoform X1. (285 aa)
HDAC5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1112 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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