STRINGSTRING
LOC112406076 LOC112406076 PROX1 PROX1 MYL3 MYL3 S1PR1 S1PR1 TBX20 TBX20 MYBPC3 MYBPC3 TNNT2 TNNT2 TNNI1 TNNI1 PKP2 PKP2 WNT5A WNT5A TNNC1 TNNC1 MYL10 MYL10 CHD7 CHD7 TCAP TCAP MYLK2 MYLK2 MED1 MED1 FOXH1 FOXH1 ANKRD1 ANKRD1 ISL1 ISL1 DSP DSP BMP10 BMP10 EDNRA EDNRA ZFPM1 ZFPM1 TGFBR1 TGFBR1 DLL4 DLL4 BMPR1A BMPR1A TGFB1 TGFB1 EGLN1 EGLN1 BMP2 BMP2 NOTCH1 NOTCH1 ENG ENG RYR2 RYR2 HAND1 HAND1 POU4F1 POU4F1 HEY2 HEY2 MYL2 MYL2 WNT2 WNT2 NOG NOG SMAD4 SMAD4 PTCD2 PTCD2 LRP2 LRP2 SMAD7 SMAD7 XIRP2 XIRP2 ZFPM2 ZFPM2 HEG1 HEG1 NKX2-5 NKX2-5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC112406076Protein HEG homolog 1-like. (419 aa)
PROX1Prospero homeobox protein 1 isoform X1. (737 aa)
MYL3Myosin light chain 3. (197 aa)
S1PR1Sphingosine 1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (382 aa)
TBX20T-box transcription factor TBX20. (449 aa)
MYBPC3Myosin-binding protein C, cardiac-type. (1277 aa)
TNNT2Troponin T, cardiac muscle isoform X1. (333 aa)
TNNI1Troponin I, slow skeletal muscle. (166 aa)
PKP2Plakophilin-2. (826 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
TNNC1Troponin C, slow skeletal and cardiac muscles. (161 aa)
MYL10Myosin regulatory light chain 10. (147 aa)
CHD7LOW QUALITY PROTEIN: chromodomain-helicase-DNA-binding protein 7. (3000 aa)
TCAPTelethonin isoform X1. (167 aa)
MYLK2Myosin light chain kinase 2, skeletal/cardiac muscle. (615 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1579 aa)
FOXH1Forkhead box protein H1. (360 aa)
ANKRD1Ankyrin repeat domain-containing protein 1. (319 aa)
ISL1Insulin gene enhancer protein ISL-1. (349 aa)
DSPDesmoplakin isoform X1. (2874 aa)
BMP10Bone morphogenetic protein 10. (423 aa)
EDNRAEndothelin-1 receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (427 aa)
ZFPM1Zinc finger protein ZFPM1. (998 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (438 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
EGLN1Egl nine homolog 1. (225 aa)
BMP2Bone morphogenetic protein 2 isoform X1. (395 aa)
NOTCH1LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 1. (2633 aa)
ENGEndoglin. (652 aa)
RYR2Ryanodine receptor 2. (4971 aa)
HAND1Heart- and neural crest derivatives-expressed protein 1. (218 aa)
POU4F1POU domain protein. (320 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif protein 2. (337 aa)
MYL2Myosin regulatory light chain 2, ventricular/cardiac muscle isoform. (166 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
SMAD4Mothers against decapentaplegic homolog. (599 aa)
PTCD2LOW QUALITY PROTEIN: pentatricopeptide repeat-containing protein 2, mitochondrial. (384 aa)
LRP2Low-density lipoprotein receptor-related protein 2 isoform X1. (4651 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
XIRP2Xin actin-binding repeat-containing protein 2 isoform X1. (3323 aa)
ZFPM2Zinc finger protein ZFPM2. (1150 aa)
HEG1Protein HEG homolog 1. (1138 aa)
NKX2-5Homeobox protein Nkx-2.5. (323 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
Server load: low (14%) [HD]