STRINGSTRING
FGF2 FGF2 BMPR1A BMPR1A SAV1 SAV1 MEF2C MEF2C TGFBR1 TGFBR1 GLI1 GLI1 BMP10 BMP10 MAPK11 MAPK11 TBX5 TBX5 TBX20 TBX20 FGF9 FGF9 ZFPM2 ZFPM2 NOG NOG TBX2 TBX2 GATA6 GATA6 WNT2 WNT2 HEY2 HEY2 FGF20 FGF20 YAP1 YAP1 TP73 TP73 NOTCH1 NOTCH1 ERBB4 ERBB4 JARID2 JARID2 PIM1 PIM1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (304 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
SAV1Protein salvador homolog 1. (384 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform X4. (483 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (438 aa)
GLI1Zinc finger protein GLI1 isoform X1. (1106 aa)
BMP10Bone morphogenetic protein 10. (423 aa)
MAPK11Mitogen-activated protein kinase. (376 aa)
TBX5T-box transcription factor TBX5. (519 aa)
TBX20T-box transcription factor TBX20. (449 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
ZFPM2Zinc finger protein ZFPM2. (1150 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
TBX2T-box transcription factor TBX2. (588 aa)
GATA6Transcription factor GATA-6. (448 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif protein 2. (337 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
YAP1Transcriptional coactivator YAP1. (416 aa)
TP73Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (718 aa)
NOTCH1LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 1. (2633 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
JARID2Protein Jumonji isoform X1. (1235 aa)
PIM1Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (349 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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