(16 nodes) Negative regulation of type I interferon-mediated signaling pathway network (Neophocaena asiaeorientalis)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

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Your Input:
	TTLL12	LOW QUALITY PROTEIN: tubulin--tyrosine ligase-like protein 12. (626 aa)
	STAT2	Signal transducer and activator of transcription. (899 aa)
	CACTIN	Cactin. (754 aa)
	YTHDF3	YTH domain-containing family protein 3. (529 aa)
	SAMHD1	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 isoform X1. (628 aa)
	NLRC5	Protein NLRC5 isoform X1. (1872 aa)
	ADAR	Double-stranded RNA-specific adenosine deaminase isoform X1. (1174 aa)
	DCST1	E3 ubiquitin-protein ligase DCST1. (707 aa)
	MUL1	Mitochondrial ubiquitin ligase activator of NFKB 1. (352 aa)
	TREX1	Three-prime repair exonuclease 1. (314 aa)
	CNOT7	CCR4-NOT transcription complex subunit 7. (285 aa)
	ISG15	Ubiquitin-like protein ISG15. (170 aa)
	METTL3	N6-adenosine-methyltransferase catalytic subunit; Belongs to the MT-A70-like family. (580 aa)
	PTPN2	Tyrosine-protein phosphatase non-receptor type. (396 aa)
	YTHDF2	YTH domain-containing family protein 2 isoform X1. (580 aa)
	LOC112392024	YTH domain-containing family protein 3-like. (292 aa)

Your Current Organism:

Neophocaena asiaeorientalis

NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAR	CACTIN	A0A341BPW0	A0A341AZ18	Double-stranded RNA-specific adenosine deaminase isoform X1.	Cactin.	0.406
ADAR	ISG15	A0A341BPW0	A0A341CQH5	Double-stranded RNA-specific adenosine deaminase isoform X1.	Ubiquitin-like protein ISG15.	0.521
ADAR	SAMHD1	A0A341BPW0	A0A341B7T8	Double-stranded RNA-specific adenosine deaminase isoform X1.	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 isoform X1.	0.554
ADAR	STAT2	A0A341BPW0	A0A341AT06	Double-stranded RNA-specific adenosine deaminase isoform X1.	Signal transducer and activator of transcription.	0.428
CACTIN	ADAR	A0A341AZ18	A0A341BPW0	Cactin.	Double-stranded RNA-specific adenosine deaminase isoform X1.	0.406
CACTIN	TTLL12	A0A341AZ18	A0A341ARM2	Cactin.	LOW QUALITY PROTEIN: tubulin--tyrosine ligase-like protein 12.	0.495
CNOT7	LOC112392024	A0A341CN18	A0A341AF61	CCR4-NOT transcription complex subunit 7.	YTH domain-containing family protein 3-like.	0.669
CNOT7	YTHDF2	A0A341CN18	A0A341D600	CCR4-NOT transcription complex subunit 7.	YTH domain-containing family protein 2 isoform X1.	0.539
CNOT7	YTHDF3	A0A341CN18	A0A341B840	CCR4-NOT transcription complex subunit 7.	YTH domain-containing family protein 3.	0.669
ISG15	ADAR	A0A341CQH5	A0A341BPW0	Ubiquitin-like protein ISG15.	Double-stranded RNA-specific adenosine deaminase isoform X1.	0.521
ISG15	SAMHD1	A0A341CQH5	A0A341B7T8	Ubiquitin-like protein ISG15.	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 isoform X1.	0.571
ISG15	STAT2	A0A341CQH5	A0A341AT06	Ubiquitin-like protein ISG15.	Signal transducer and activator of transcription.	0.794
LOC112392024	CNOT7	A0A341AF61	A0A341CN18	YTH domain-containing family protein 3-like.	CCR4-NOT transcription complex subunit 7.	0.669
LOC112392024	METTL3	A0A341AF61	A0A341CRT6	YTH domain-containing family protein 3-like.	N6-adenosine-methyltransferase catalytic subunit; Belongs to the MT-A70-like family.	0.678
METTL3	LOC112392024	A0A341CRT6	A0A341AF61	N6-adenosine-methyltransferase catalytic subunit; Belongs to the MT-A70-like family.	YTH domain-containing family protein 3-like.	0.678
METTL3	YTHDF2	A0A341CRT6	A0A341D600	N6-adenosine-methyltransferase catalytic subunit; Belongs to the MT-A70-like family.	YTH domain-containing family protein 2 isoform X1.	0.761
METTL3	YTHDF3	A0A341CRT6	A0A341B840	N6-adenosine-methyltransferase catalytic subunit; Belongs to the MT-A70-like family.	YTH domain-containing family protein 3.	0.678
PTPN2	STAT2	A0A341CXN1	A0A341AT06	Tyrosine-protein phosphatase non-receptor type.	Signal transducer and activator of transcription.	0.915
SAMHD1	ADAR	A0A341B7T8	A0A341BPW0	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 isoform X1.	Double-stranded RNA-specific adenosine deaminase isoform X1.	0.554
SAMHD1	ISG15	A0A341B7T8	A0A341CQH5	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 isoform X1.	Ubiquitin-like protein ISG15.	0.571