20 items (Neophocaena asiaeorientalis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PML	Protein PML isoform X1. (965 aa)
	AREG	Amphiregulin isoform X1. (253 aa)
	CSMD1	CUB and sushi domain-containing protein 1. (3778 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
	PHB2	Prohibitin. (299 aa)
	BTRC	F-box/WD repeat-containing protein 1A isoform X1. (605 aa)
	VDR	Vitamin D3 receptor. (427 aa)
	LOC112394306	C-C motif chemokine. (97 aa)
	DDR1	Tyrosine-protein kinase receptor. (932 aa)
	CSF1	Macrophage colony-stimulating factor 1. (513 aa)
	TBX3	LOW QUALITY PROTEIN: T-box transcription factor TBX3. (734 aa)
	MED1	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1579 aa)
	SRC	Tyrosine-protein kinase. (601 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
	ESR1	Estrogen receptor. (604 aa)
	KDM5B	Lysine-specific demethylase 5B. (1311 aa)
	LRP5	Low-density lipoprotein receptor-related protein 5 isoform X1. (1461 aa)
	EPHA2	Ephrin type-A receptor 2. (975 aa)
	AR	Androgen receptor isoform X1. (893 aa)
	CSMD2	CUB and sushi domain-containing protein 2. (3656 aa)

Your Current Organism:

Neophocaena asiaeorientalis

NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AR	ESR1	A0A341BZY8	A0A341BP96	Androgen receptor isoform X1.	Estrogen receptor.	0.608
AR	MED1	A0A341BZY8	A0A341B6X9	Androgen receptor isoform X1.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.681
AR	SRC	A0A341BZY8	A0A341B9I2	Androgen receptor isoform X1.	Tyrosine-protein kinase.	0.706
AREG	ESR1	A0A341C5Y1	A0A341BP96	Amphiregulin isoform X1.	Estrogen receptor.	0.459
AREG	SRC	A0A341C5Y1	A0A341B9I2	Amphiregulin isoform X1.	Tyrosine-protein kinase.	0.731
CSF1	EPHA2	A0A341B4Y9	A0A341BVH9	Macrophage colony-stimulating factor 1.	Ephrin type-A receptor 2.	0.843
CSF1	LOC112394306	A0A341B4Y9	A0A341AU57	Macrophage colony-stimulating factor 1.	C-C motif chemokine.	0.579
CSF1	SRC	A0A341B4Y9	A0A341B9I2	Macrophage colony-stimulating factor 1.	Tyrosine-protein kinase.	0.699
CSF1	TGFB1	A0A341B4Y9	A0A341DAG8	Macrophage colony-stimulating factor 1.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.694
EPHA2	CSF1	A0A341BVH9	A0A341B4Y9	Ephrin type-A receptor 2.	Macrophage colony-stimulating factor 1.	0.843
ESR1	AR	A0A341BP96	A0A341BZY8	Estrogen receptor.	Androgen receptor isoform X1.	0.608
ESR1	AREG	A0A341BP96	A0A341C5Y1	Estrogen receptor.	Amphiregulin isoform X1.	0.459
ESR1	MED1	A0A341BP96	A0A341B6X9	Estrogen receptor.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.981
ESR1	PHB2	A0A341BP96	A0A341AGD9	Estrogen receptor.	Prohibitin.	0.834
ESR1	SRC	A0A341BP96	A0A341B9I2	Estrogen receptor.	Tyrosine-protein kinase.	0.994
ESR1	TGFB1	A0A341BP96	A0A341DAG8	Estrogen receptor.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.572
KDM5B	MED1	A0A341BRM9	A0A341B6X9	Lysine-specific demethylase 5B.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.489
LOC112394306	CSF1	A0A341AU57	A0A341B4Y9	C-C motif chemokine.	Macrophage colony-stimulating factor 1.	0.579
LRP5	SRC	A0A341BRX5	A0A341B9I2	Low-density lipoprotein receptor-related protein 5 isoform X1.	Tyrosine-protein kinase.	0.556
LRP5	WNT5A	A0A341BRX5	A0A341BKG2	Low-density lipoprotein receptor-related protein 5 isoform X1.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.956