STRINGSTRING
ADPRHL1 ADPRHL1 ALCAM ALCAM CYFIP1 CYFIP1 WNT5A WNT5A BIN3 BIN3 NDEL1 NDEL1 ESR1 ESR1 KDM5B KDM5B CDH4 CDH4 S1PR1 S1PR1 LOC112403425 LOC112403425 JADE2 JADE2 POU4F3 POU4F3 NRP2 NRP2 LOC112395235 LOC112395235 SHH SHH NRN1 NRN1 LAMB2 LAMB2 LOC112394306 LOC112394306 MST1 MST1 SEMA3F SEMA3F LLPH LLPH IST1 IST1 RARG RARG FLRT3 FLRT3 EDNRA EDNRA POU4F2 POU4F2 SLIT1 SLIT1 BMP4 BMP4 LZTS2 LZTS2 LOC112392005 LOC112392005 NRN1L NRN1L HOXD13 HOXD13 PAK6 PAK6 FMN1 FMN1 APP APP LHX2 LHX2 NOTCH1 NOTCH1 SSNA1 SSNA1 SEMA7A SEMA7A DCX DCX CYFIP2 CYFIP2 SOX9 SOX9 SPRY2 SPRY2 YAP1 YAP1 PRKCZ PRKCZ DVL1 DVL1 LOC112409616 LOC112409616 LOC112409615 LOC112409615 EPB41L5 EPB41L5 TNR TNR TNN TNN LOC112407988 LOC112407988 MED12 MED12 IMPACT IMPACT LHX1 LHX1 TBX2 TBX2 WNT11 WNT11 LOC112407979 LOC112407979 SEMA5B SEMA5B VGLL2 VGLL2 MAP1B MAP1B DCLK1 DCLK1 SPART SPART CUNH9orf72 CUNH9orf72 HDAC6 HDAC6 NDN NDN NIN NIN TGFB1 TGFB1 LPAR3 LPAR3 PTK7 PTK7 SPAG6 SPAG6 MESP1 MESP1 IQGAP1 IQGAP1 ITGB1 ITGB1 SRF SRF RDH10 RDH10 WNT3A WNT3A AUTS2 AUTS2 SFRP1 SFRP1 COBL COBL ADPRH ADPRH EDN1 EDN1 PLXNA1 PLXNA1 LOC112412440 LOC112412440 EMX1 EMX1 KIF26B KIF26B AREG AREG CTNNB1 CTNNB1 SEMA5A SEMA5A SLIT3 SLIT3 CDKL3 CDKL3 LOC112395257 LOC112395257 DDR1 DDR1 ULK1 ULK1 SPG11 SPG11 STK11 STK11 LOC112396051 LOC112396051 WASF1 WASF1 FGF10 FGF10 EXT1 EXT1 VCL VCL TRIM28 TRIM28 CSF1 CSF1 LOC112397547 LOC112397547 SLIT2 SLIT2 MED1 MED1 EFNA5 EFNA5 EDN2 EDN2 RYK RYK TMEM108 TMEM108 SPRY1 SPRY1 PLXNA3 PLXNA3 LIMK1 LIMK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADPRHL1Protein ADP-ribosylarginine hydrolase-like protein 1. (354 aa)
ALCAMCD166 antigen isoform X1. (583 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
BIN3Bridging integrator 3 isoform X1. (253 aa)
NDEL1Nuclear distribution protein nudE-like 1 isoform X1. (346 aa)
ESR1Estrogen receptor. (604 aa)
KDM5BLysine-specific demethylase 5B. (1311 aa)
CDH4Cadherin-4 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (884 aa)
S1PR1Sphingosine 1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (382 aa)
LOC112403425Protein kinase C zeta type-like. (85 aa)
JADE2E3 ubiquitin-protein ligase Jade-2 isoform X1. (827 aa)
POU4F3POU domain protein. (338 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (931 aa)
LOC112395235Ras-associated and pleckstrin homology domains-containing protein 1-like. (426 aa)
SHHSonic hedgehog protein. (328 aa)
NRN1Neuritin. (142 aa)
LAMB2Laminin subunit beta-2. (1801 aa)
LOC112394306C-C motif chemokine. (97 aa)
MST1LOW QUALITY PROTEIN: hepatocyte growth factor-like protein; Belongs to the peptidase S1 family. (732 aa)
SEMA3Fsemaphorin-3F; Belongs to the semaphorin family. (744 aa)
LLPHProtein LLP homolog. (127 aa)
IST1IST1 homolog isoform X1. (376 aa)
RARGRetinoic acid receptor gamma isoform X2. (458 aa)
FLRT3Leucine-rich repeat transmembrane protein FLRT3. (649 aa)
EDNRAEndothelin-1 receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (427 aa)
POU4F2POU domain protein. (408 aa)
SLIT1Slit homolog 1 protein. (1514 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (420 aa)
LZTS2Leucine zipper putative tumor suppressor 2; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta- catenin. (664 aa)
LOC112392005Laminin subunit beta-1-like. (78 aa)
NRN1LNeuritin-like protein. (251 aa)
HOXD13Homeobox protein Hox-D13. (264 aa)
PAK6Non-specific serine/threonine protein kinase. (675 aa)
FMN1Formin-1 isoform X1. (1420 aa)
APPAmyloid-beta A4 protein isoform X1. (767 aa)
LHX2LIM/homeobox protein Lhx2. (406 aa)
NOTCH1LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 1. (2633 aa)
SSNA1Sjoegren syndrome nuclear autoantigen 1. (119 aa)
SEMA7Asemaphorin-7A; Belongs to the semaphorin family. (665 aa)
DCXNeuronal migration protein doublecortin. (365 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
SOX9Transcription factor SOX-9. (486 aa)
SPRY2Protein sprouty homolog 2. (315 aa)
YAP1Transcriptional coactivator YAP1. (416 aa)
PRKCZLOW QUALITY PROTEIN: protein kinase C zeta type; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (546 aa)
DVL1Segment polarity protein dishevelled homolog DVL-1. (706 aa)
LOC112409616Probable ubiquitin carboxyl-terminal hydrolase FAF-X; Belongs to the peptidase C19 family. (2060 aa)
LOC112409615Probable ubiquitin carboxyl-terminal hydrolase FAF-X. (235 aa)
EPB41L5Band 4.1-like protein 5 isoform X1. (746 aa)
TNRtenascin-R. (1358 aa)
TNNtenascin-N. (1296 aa)
LOC112407988Secreted frizzled-related protein 2. (294 aa)
MED12Mediator of RNA polymerase II transcription subunit 12. (2097 aa)
IMPACTProtein IMPACT isoform X1. (318 aa)
LHX1LIM/homeobox protein Lhx1. (406 aa)
TBX2T-box transcription factor TBX2. (588 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
LOC112407979Secreted frizzled-related protein 2-like. (105 aa)
SEMA5Bsemaphorin-5B isoform X1. (1102 aa)
VGLL2LOW QUALITY PROTEIN: transcription cofactor vestigial-like protein 2. (314 aa)
MAP1BMicrotubule-associated protein 1B. (2474 aa)
DCLK1Serine/threonine-protein kinase DCLK1 isoform X1. (741 aa)
SPARTSpartin isoform X1. (667 aa)
CUNH9orf72Guanine nucleotide exchange C9orf72 homolog isoform X1. (481 aa)
HDAC6Histone deacetylase 6 isoform X1. (1176 aa)
NDNNecdin. (325 aa)
NINNinein isoform X1. (2180 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
LPAR3Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family. (355 aa)
PTK7Inactive tyrosine-protein kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1070 aa)
SPAG6Sperm-associated antigen 6. (509 aa)
MESP1Mesoderm posterior protein 1. (265 aa)
IQGAP1Ras GTPase-activating-like protein IQGAP1. (1657 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
SRFSerum response factor isoform X1. (535 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
AUTS2LOW QUALITY PROTEIN: autism susceptibility gene 2 protein. (803 aa)
SFRP1Secreted frizzled-related protein 1. (296 aa)
COBLProtein cordon-bleu isoform X1. (1274 aa)
ADPRHADP-ribosylarginine hydrolase. (373 aa)
EDN1Endothelin-1. (202 aa)
PLXNA1LOW QUALITY PROTEIN: plexin-A1. (2367 aa)
LOC112412440Autism susceptibility gene 2 protein-like. (325 aa)
EMX1Homeobox protein EMX1. (288 aa)
KIF26BLOW QUALITY PROTEIN: kinesin-like protein KIF26B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2103 aa)
AREGAmphiregulin isoform X1. (253 aa)
CTNNB1Catenin beta-1. (781 aa)
SEMA5Asemaphorin-5A isoform X1. (1073 aa)
SLIT3Slit homolog 3 protein isoform X2. (1523 aa)
CDKL3Cyclin-dependent kinase-like 3. (556 aa)
LOC112395257Ras-associated and pleckstrin homology domains-containing protein 1-like. (644 aa)
DDR1Tyrosine-protein kinase receptor. (932 aa)
ULK1Serine/threonine-protein kinase ULK1 isoform X1. (972 aa)
SPG11Spatacsin isoform X1. (2445 aa)
STK11Serine/threonine-protein kinase STK11 isoform X1. (546 aa)
LOC112396051Probable ubiquitin carboxyl-terminal hydrolase FAF-X isoform X1; Belongs to the peptidase C19 family. (2556 aa)
WASF1wiskott-Aldrich syndrome protein family member 1. (559 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
EXT1Exostosin-1; Belongs to the glycosyltransferase 47 family. (746 aa)
VCLVinculin isoform X2. (1134 aa)
TRIM28Transcription intermediary factor 1-beta. (983 aa)
CSF1Macrophage colony-stimulating factor 1. (513 aa)
LOC112397547Slit homolog 2 protein-like. (162 aa)
SLIT2Slit homolog 2 protein. (1286 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1579 aa)
EFNA5ephrin-A5 isoform X1; Belongs to the ephrin family. (228 aa)
EDN2Endothelin-2. (177 aa)
RYKTyrosine-protein kinase RYK. (705 aa)
TMEM108Transmembrane protein 108. (583 aa)
SPRY1Protein sprouty homolog 1. (319 aa)
PLXNA3plexin-A3. (1569 aa)
LIMK1LIM domain kinase 1. (594 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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