STRINGSTRING
WNT11 WNT11 LEMD2 LEMD2 MESP1 MESP1 BMPR1A BMPR1A EMP2 EMP2 WNT5A WNT5A SMARCD3 SMARCD3 LRP2 LRP2 AXIN2 AXIN2 LOC112390775 LOC112390775 MEF2C MEF2C BMP4 BMP4 ISL1 ISL1 EXT1 EXT1 FOXH1 FOXH1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
LEMD2LEM domain-containing protein 2. (417 aa)
MESP1Mesoderm posterior protein 1. (265 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
EMP2Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
SMARCD3annotation not available (495 aa)
LRP2Low-density lipoprotein receptor-related protein 2 isoform X1. (4651 aa)
AXIN2Axin-2. (720 aa)
LOC112390775Folate receptor alpha-like. (251 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform X4. (483 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (420 aa)
ISL1Insulin gene enhancer protein ISL-1. (349 aa)
EXT1Exostosin-1; Belongs to the glycosyltransferase 47 family. (746 aa)
FOXH1Forkhead box protein H1. (360 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
Server load: low (16%) [HD]