STRINGSTRING
FGF2 FGF2 SRC SRC MSX1 MSX1 MED1 MED1 AR AR PTCH1 PTCH1 AREG AREG HOXA5 HOXA5 TNFSF11 TNFSF11 WNT2 WNT2 ORAI1 ORAI1 WNT3 WNT3 PML PML SMO SMO ERBB4 ERBB4 MAPK1 MAPK1 ZNF703 ZNF703 LRRC1 LRRC1 CSMD2 CSMD2 SOSTDC1 SOSTDC1 TGFB1 TGFB1 CSMD1 CSMD1 CEBPB CEBPB EPHA2 EPHA2 IRF6 IRF6 CCND1 CCND1 LRP5 LRP5 KDM5B KDM5B NTN1 NTN1 HIF1A HIF1A ESR1 ESR1 IQGAP3 IQGAP3 LATS1 LATS1 WNT5A WNT5A PHB2 PHB2 FOXF1 FOXF1 ATP2C2 ATP2C2 BTRC BTRC FOXB1 FOXB1 AGAP2 AGAP2 VDR VDR STAT6 STAT6 ID2 ID2 MST1 MST1 LOC112394306 LOC112394306 DDR1 DDR1 FGF10 FGF10 SCRIB SCRIB CSF1 CSF1 TBX3 TBX3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (304 aa)
SRCTyrosine-protein kinase. (601 aa)
MSX1Homeobox protein MSX-1. (303 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1579 aa)
ARAndrogen receptor isoform X1. (893 aa)
PTCH1Protein patched homolog 1 isoform X1. (1297 aa)
AREGAmphiregulin isoform X1. (253 aa)
HOXA5Homeobox protein Hox-A5. (381 aa)
TNFSF11Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family. (323 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
ORAI1LOW QUALITY PROTEIN: calcium release-activated calcium channel protein 1. (410 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (453 aa)
PMLProtein PML isoform X1. (965 aa)
SMOSmoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (783 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
MAPK1Mitogen-activated protein kinase. (343 aa)
ZNF703Zinc finger protein 703. (620 aa)
LRRC1Leucine-rich repeat-containing protein 1. (443 aa)
CSMD2CUB and sushi domain-containing protein 2. (3656 aa)
SOSTDC1Sclerostin domain-containing protein 1. (206 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
CSMD1CUB and sushi domain-containing protein 1. (3778 aa)
CEBPBCCAAT/enhancer-binding protein. (346 aa)
EPHA2Ephrin type-A receptor 2. (975 aa)
IRF6Interferon regulatory factor 6 isoform X1. (467 aa)
CCND1G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa)
LRP5Low-density lipoprotein receptor-related protein 5 isoform X1. (1461 aa)
KDM5BLysine-specific demethylase 5B. (1311 aa)
NTN1Netrin-1. (604 aa)
HIF1AHypoxia-inducible factor 1-alpha. (823 aa)
ESR1Estrogen receptor. (604 aa)
IQGAP3Ras GTPase-activating-like protein IQGAP3. (1633 aa)
LATS1Serine/threonine-protein kinase LATS1. (1128 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
PHB2Prohibitin. (299 aa)
FOXF1Forkhead box protein F1. (375 aa)
ATP2C2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (975 aa)
BTRCF-box/WD repeat-containing protein 1A isoform X1. (605 aa)
FOXB1Forkhead box protein B1. (325 aa)
AGAP2arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 isoform X1. (836 aa)
VDRVitamin D3 receptor. (427 aa)
STAT6Signal transducer and activator of transcription. (859 aa)
ID2DNA-binding protein inhibitor ID-2. (134 aa)
MST1LOW QUALITY PROTEIN: hepatocyte growth factor-like protein; Belongs to the peptidase S1 family. (732 aa)
LOC112394306C-C motif chemokine. (97 aa)
DDR1Tyrosine-protein kinase receptor. (932 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
SCRIBLOW QUALITY PROTEIN: protein scribble homolog. (1575 aa)
CSF1Macrophage colony-stimulating factor 1. (513 aa)
TBX3LOW QUALITY PROTEIN: T-box transcription factor TBX3. (734 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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