STRINGSTRING
PIEZO1 PIEZO1 RPE65 RPE65 PKD2L1 PKD2L1 TNFRSF1A TNFRSF1A LOC112392028 LOC112392028 SCNN1A SCNN1A LTBR LTBR CCND2 CCND2 RHNO1 RHNO1 BMF BMF POLK POLK RAD51 RAD51 INO80 INO80 YBX3 YBX3 MAP3K20 MAP3K20 CAPN3 CAPN3 OPN4 OPN4 SLC2A4 SLC2A4 RP1 RP1 RGR RGR IL1B IL1B LRRC8D LRRC8D FAS FAS MAPK3 MAPK3 SCNN1G SCNN1G EPO EPO COL1A1 COL1A1 SCNN1B SCNN1B ERCC4 ERCC4 LRRC8E LRRC8E MCOLN1 MCOLN1 NEUROD2 NEUROD2 PRKCD PRKCD TNFSF14 TNFSF14 RAB11B RAB11B LOC112400718 LOC112400718 PPID PPID EIF2S1 EIF2S1 RDH11 RDH11 N4BP1 N4BP1 MMP2 MMP2 NOX1 NOX1 HUS1 HUS1 CLOCK CLOCK REST REST MMP9 MMP9 CD40 CD40 GRM1 GRM1 GTF2H5 GTF2H5 INSRR INSRR IRF1 IRF1 AQP10 AQP10 TNKS1BP1 TNKS1BP1 RAD9A RAD9A AURKB AURKB DDB1 DDB1 KCNK4 KCNK4 HRAS HRAS TIMP1 TIMP1 DDB2 DDB2 CASP9 CASP9 TNFRSF8 TNFRSF8 BAD BAD FADD FADD TMEM109 TMEM109 ZBTB1 ZBTB1 LOC112403078 LOC112403078 PCK1 PCK1 PTGS2 PTGS2 NUCKS1 NUCKS1 RIPOR2 RIPOR2 GPLD1 GPLD1 INTS7 INTS7 CDC25A CDC25A GPR88 GPR88 TREX1 TREX1 EGR1 EGR1 PIK3R1 PIK3R1 MAP2K4 MAP2K4 NFATC4 NFATC4 PDE2A PDE2A MFAP4 MFAP4 LIG4 LIG4 SDE2 SDE2 CRYAB CRYAB GNB5 GNB5 NIPBL NIPBL BRCC3 BRCC3 ADSS ADSS RAD1 RAD1 PTGER4 PTGER4 AQP1 AQP1 CRADD CRADD DHRS12 DHRS12 BRCA2 BRCA2 PIK3CA PIK3CA KCNK18 KCNK18 BAG3 BAG3 SLC12A6 SLC12A6 RHO RHO STK39 STK39 TP53INP1 TP53INP1 NET1 NET1 SMPD1 SMPD1 USP47 USP47 CASP8 CASP8 MYD88 MYD88 LOC112407979 LOC112407979 F11R F11R WNT11 WNT11 IMPACT IMPACT CASP10 CASP10 CASP2 CASP2 LOC112407988 LOC112407988 RAD9B RAD9B YY1 YY1 HVCN1 HVCN1 TMEM150C TMEM150C CREBBP CREBBP PTPRK PTPRK DDX3X DDX3X TLR3 TLR3 TLR7 TLR7 BDKRB2 BDKRB2 NOC2L NOC2L YAP1 YAP1 SOX9 SOX9 TLR8 TLR8 RGS9 RGS9 SPIDR SPIDR SLC4A11 SLC4A11 ACTR5 ACTR5 RCSD1 RCSD1 TRPM1 TRPM1 TRPV4 TRPV4 BRCA1 BRCA1 PALM PALM HSF1 HSF1 OPN3 OPN3 CNN2 CNN2 PLEC PLEC GNA11 GNA11 ECT2 ECT2 ANKRD1 ANKRD1 CHEK1 CHEK1 RHBDD1 RHBDD1 LOC112396076 LOC112396076 FBXO4 FBXO4 PARP1 PARP1 ZFP36L1 ZFP36L1 STK11 STK11 RS1 RS1 LOC112395818 LOC112395818 CUL4B CUL4B MAP3K2 MAP3K2 GNAT1 GNAT1 ZMPSTE24 ZMPSTE24 AQP2 AQP2 EP300 EP300 SLC38A3 SLC38A3 XRCC6 XRCC6 ASIC1 ASIC1 AQP5 AQP5 TANK TANK TRPV1 TRPV1 GPR68 GPR68 SLC24A4 SLC24A4 PKD2 PKD2 GADD45A GADD45A NFKB1 NFKB1 XPA XPA CAPN9 CAPN9 MAPK13 MAPK13 CDKN1A CDKN1A BAK1 BAK1 BLM BLM SIRT1 SIRT1 OPN5 OPN5 SLC9A1 SLC9A1 ATM ATM POLH POLH KDM1A KDM1A WNK3 WNK3 TMEM161A TMEM161A PBK PBK BCL10 BCL10 NEDD4 NEDD4 TGFB1 TGFB1 ERCC1 ERCC1 CERS1 CERS1 BBC3 BBC3 POLD1 POLD1 RUVBL2 RUVBL2 CHEK2 CHEK2 DHX36 DHX36 ATR ATR MAP3K14 MAP3K14 TLK2 TLK2 METTL3 METTL3 GRB2 GRB2 LOC112410884 LOC112410884 PRAP1 PRAP1 BNIP3 BNIP3 POLD3 POLD3 XRCC5 XRCC5 XPC XPC CUNH9orf116 CUNH9orf116 PIEZO2 PIEZO2 OPN1SW OPN1SW CRB1 CRB1 COPS9 COPS9 PCNA PCNA BABAM2 BABAM2 SFRP1 SFRP1 WRN WRN FIGNL1 FIGNL1 MAP3K1 MAP3K1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIEZO1Piezo-type mechanosensitive ion channel component. (2504 aa)
RPE65Retinoid isomerohydrolase. (533 aa)
PKD2L1LOW QUALITY PROTEIN: polycystic kidney disease 2-like 1 protein. (800 aa)
TNFRSF1ATumor necrosis factor receptor superfamily member 1A. (445 aa)
LOC112392028RE1-silencing transcription factor-like. (305 aa)
SCNN1AAmiloride-sensitive sodium channel subunit alpha; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (648 aa)
LTBRTumor necrosis factor receptor superfamily member 3. (421 aa)
CCND2G1/S-specific cyclin-D2; Belongs to the cyclin family. (289 aa)
RHNO1RAD9, HUS1, RAD1-interacting nuclear orphan protein 1. (240 aa)
BMFBcl-2-modifying factor. (241 aa)
POLKDNA polymerase kappa. (878 aa)
RAD51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa)
INO80DNA helicase INO80 isoform X1. (1563 aa)
YBX3Y-box-binding protein 3. (348 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20 isoform X1. (940 aa)
CAPN3Calpain-3 isoform X4; Belongs to the peptidase C2 family. (773 aa)
OPN4Melanopsin. (478 aa)
SLC2A4Solute carrier family 2, facilitated glucose transporter member 4 isoform X1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (603 aa)
RP1Oxygen-regulated protein 1. (2142 aa)
RGRRPE-retinal G protein-coupled receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily. (295 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (266 aa)
LRRC8DVolume-regulated anion channel subunit LRRC8D. (855 aa)
FASTumor necrosis factor receptor superfamily member 6 isoform X1. (334 aa)
MAPK3Mitogen-activated protein kinase 3. (265 aa)
SCNN1GAmiloride-sensitive sodium channel subunit gamma; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (651 aa)
EPOErythropoietin. (266 aa)
COL1A1Collagen alpha-1(I) chain. (1463 aa)
SCNN1BAmiloride-sensitive sodium channel subunit beta; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (641 aa)
ERCC4DNA repair endonuclease XPF. (916 aa)
LRRC8EVolume-regulated anion channel subunit LRRC8E. (795 aa)
MCOLN1Mucolipin-1. (582 aa)
NEUROD2Neurogenic differentiation factor. (382 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (675 aa)
TNFSF14Tumor necrosis factor ligand superfamily member 14 isoform X1; Belongs to the tumor necrosis factor family. (311 aa)
RAB11BRas-related protein Rab-11B. (218 aa)
LOC112400718Hyaluronidase. (781 aa)
PPIDPeptidyl-prolyl cis-trans isomerase D isoform X1. (370 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit 1. (315 aa)
RDH11Retinol dehydrogenase 11 isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (316 aa)
N4BP1NEDD4-binding protein 1. (897 aa)
MMP272 kDa type IV collagenase. (661 aa)
NOX1LOW QUALITY PROTEIN: NADPH oxidase 1. (569 aa)
HUS1Checkpoint protein; Belongs to the HUS1 family. (227 aa)
CLOCKCircadian locomoter output cycles protein kaput. (848 aa)
RESTRE1-silencing transcription factor isoform X2. (450 aa)
MMP9Matrix metalloproteinase-9. (709 aa)
CD40Tumor necrosis factor receptor superfamily member 5 isoform X1. (293 aa)
GRM1Metabotropic glutamate receptor 1 isoform X1. (1194 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
INSRRTyrosine-protein kinase receptor. (1293 aa)
IRF1Interferon regulatory factor. (322 aa)
AQP10LOW QUALITY PROTEIN: aquaporin-10; Belongs to the MIP/aquaporin (TC 1.A.8) family. (301 aa)
TNKS1BP1182 kDa tankyrase-1-binding protein isoform X1. (1718 aa)
RAD9ACell cycle checkpoint control protein; Belongs to the rad9 family. (420 aa)
AURKBAurora kinase B isoform X1; Belongs to the protein kinase superfamily. (345 aa)
DDB1DNA damage-binding protein 1. (1140 aa)
KCNK4Potassium channel subfamily K member 4; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (401 aa)
HRASGTPase HRas isoform X1. (189 aa)
TIMP1Metalloproteinase inhibitor 1. (260 aa)
DDB2DNA damage-binding protein 2 isoform X1. (457 aa)
CASP9Caspase-9; Belongs to the peptidase C14A family. (442 aa)
TNFRSF8Tumor necrosis factor receptor superfamily member 8 isoform X1. (599 aa)
BADBcl2-associated agonist of cell death. (168 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (211 aa)
TMEM109Transmembrane protein 109 isoform X1. (254 aa)
ZBTB1Zinc finger and BTB domain-containing protein 1. (713 aa)
LOC112403078Uncharacterized protein LOC112403078 isoform X1. (175 aa)
PCK1Phosphoenolpyruvate carboxykinase, cytosolic [GTP]. (622 aa)
PTGS2Prostaglandin G/H synthase 2. (604 aa)
NUCKS1Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1. (137 aa)
RIPOR2Rho family-interacting cell polarization regulator 2 isoform X6. (1097 aa)
GPLD1Phosphatidylinositol-glycan-specific phospholipase D. (849 aa)
INTS7Integrator complex subunit 7. (962 aa)
CDC25AM-phase inducer phosphatase 1 isoform X1. (524 aa)
GPR88Probable G-protein coupled receptor 88. (382 aa)
TREX1Three-prime repair exonuclease 1. (314 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (531 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
MAP2K4Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (362 aa)
NFATC4Nuclear factor of activated T-cells, cytoplasmic 4 isoform X1. (831 aa)
PDE2APhosphodiesterase. (964 aa)
MFAP4LOW QUALITY PROTEIN: microfibril-associated glycoprotein 4. (225 aa)
LIG4DNA ligase. (911 aa)
SDE2Replication stress response regulator SDE2 isoform X1. (453 aa)
CRYABAlpha-crystallin B chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (175 aa)
GNB5Guanine nucleotide-binding protein subunit beta-5 isoform X3. (414 aa)
NIPBLNipped-B protein. (2803 aa)
BRCC3Lys-63-specific deubiquitinase BRCC36 isoform X1. (316 aa)
ADSSAdenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (456 aa)
RAD1Cell cycle checkpoint protein RAD1. (279 aa)
PTGER4Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family. (486 aa)
AQP1Aquaporin-1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
CRADDDeath domain-containing protein CRADD isoform X1. (199 aa)
DHRS12Dehydrogenase/reductase SDR family member 12 isoform X1. (352 aa)
BRCA2Breast cancer type 2 susceptibility protein. (3435 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
KCNK18LOW QUALITY PROTEIN: potassium channel subfamily K member 18; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (379 aa)
BAG3BAG family molecular chaperone regulator 3. (577 aa)
SLC12A6Solute carrier family 12 member 6 isoform X1. (1150 aa)
RHORhodopsin. (348 aa)
STK39STE20/SPS1-related proline-alanine-rich protein kinase isoform X1. (432 aa)
TP53INP1Tumor protein p53-inducible nuclear protein 1 isoform X1. (240 aa)
NET1Neuroepithelial cell-transforming gene 1 protein isoform X1. (548 aa)
SMPD1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (625 aa)
USP47Ubiquitin carboxyl-terminal hydrolase 47 isoform X1; Belongs to the peptidase C19 family. (1355 aa)
CASP8Caspase-8 isoform X1; Belongs to the peptidase C14A family. (497 aa)
MYD88Myeloid differentiation primary response protein MyD88. (182 aa)
LOC112407979Secreted frizzled-related protein 2-like. (105 aa)
F11RJunctional adhesion molecule A isoform X1. (299 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
IMPACTProtein IMPACT isoform X1. (318 aa)
CASP10Caspase-10; Belongs to the peptidase C14A family. (517 aa)
CASP2Caspase-2 isoform X1; Belongs to the peptidase C14A family. (452 aa)
LOC112407988Secreted frizzled-related protein 2. (294 aa)
RAD9BCell cycle checkpoint control protein; Belongs to the rad9 family. (413 aa)
YY1Transcriptional repressor protein YY1. (412 aa)
HVCN1Voltage-gated hydrogen channel 1 isoform X1. (293 aa)
TMEM150CTransmembrane protein 150C. (249 aa)
CREBBPCREB-binding protein. (2443 aa)
PTPRKReceptor-type tyrosine-protein phosphatase kappa isoform X1. (1439 aa)
DDX3XATP-dependent RNA helicase DDX3X isoform X1; Belongs to the DEAD box helicase family. (662 aa)
TLR3Toll-like receptor 3 isoform X2; Belongs to the Toll-like receptor family. (956 aa)
TLR7Toll-like receptor 7 isoform X1. (1086 aa)
BDKRB2B2 bradykinin receptor; Belongs to the G-protein coupled receptor 1 family. (360 aa)
NOC2LNucleolar complex protein 2 homolog isoform X1. (738 aa)
YAP1Transcriptional coactivator YAP1. (416 aa)
SOX9Transcription factor SOX-9. (486 aa)
TLR8Toll-like receptor 8; Belongs to the Toll-like receptor family. (1035 aa)
RGS9Regulator of G-protein signaling 9. (707 aa)
SPIDRDNA repair-scaffolding protein isoform X1. (933 aa)
SLC4A11Sodium bicarbonate transporter-like protein 11 isoform X1. (950 aa)
ACTR5Actin-related protein 5; Belongs to the actin family. (596 aa)
RCSD1capZ-interacting protein isoform X1. (478 aa)
TRPM1Transient receptor potential cation channel subfamily M member 1. (1660 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4 isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (881 aa)
BRCA1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1870 aa)
PALMParalemmin-1 isoform X1. (391 aa)
HSF1Heat shock factor protein 1 isoform X1. (526 aa)
OPN3LOW QUALITY PROTEIN: opsin-3; Belongs to the G-protein coupled receptor 1 family. (521 aa)
CNN2Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (309 aa)
PLECLOW QUALITY PROTEIN: plectin. (4609 aa)
GNA11Guanine nucleotide-binding protein subunit alpha-11. (337 aa)
ECT2Protein ECT2 isoform X1. (973 aa)
ANKRD1Ankyrin repeat domain-containing protein 1. (319 aa)
CHEK1Serine/threonine-protein kinase Chk1; Belongs to the protein kinase superfamily. (476 aa)
RHBDD1Rhomboid-related protein 4. (316 aa)
LOC112396076ATP-dependent RNA helicase DDX3X-like; Belongs to the DEAD box helicase family. (656 aa)
FBXO4F-box only protein 4 isoform X1. (248 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1013 aa)
ZFP36L1mRNA decay activator protein ZFP36L1. (338 aa)
STK11Serine/threonine-protein kinase STK11 isoform X1. (546 aa)
RS1Retinoschisin. (224 aa)
LOC112395818LOW QUALITY PROTEIN: cullin-4B-like; Belongs to the cullin family. (630 aa)
CUL4Bcullin-4B isoform X1; Belongs to the cullin family. (899 aa)
MAP3K2Mitogen-activated protein kinase kinase kinase 2. (620 aa)
GNAT1Guanine nucleotide-binding protein G(T) subunit alpha-1. (350 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (473 aa)
AQP2Aquaporin-2 isoform X1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
EP300Histone acetyltransferase p300. (2399 aa)
SLC38A3Sodium-coupled neutral amino acid transporter 3 isoform X1. (531 aa)
XRCC6X-ray repair cross-complementing protein 6 isoform X1. (654 aa)
ASIC1Acid-sensing ion channel 1 isoform X1; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (559 aa)
AQP5Aquaporin-5; Belongs to the MIP/aquaporin (TC 1.A.8) family. (261 aa)
TANKTRAF family member-associated NF-kappa-B activator isoform X1. (425 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (837 aa)
GPR68Ovarian cancer G-protein coupled receptor 1; Belongs to the G-protein coupled receptor 1 family. (371 aa)
SLC24A4Sodium/potassium/calcium exchanger 4; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (568 aa)
PKD2Polycystin-2 isoform X1. (782 aa)
GADD45AGrowth arrest and DNA damage-inducible protein GADD45 alpha. (165 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit isoform X1. (977 aa)
XPADNA repair protein complementing XP-A cells. (273 aa)
CAPN9LOW QUALITY PROTEIN: calpain-9; Belongs to the peptidase C2 family. (391 aa)
MAPK13Mitogen-activated protein kinase. (366 aa)
CDKN1ACyclin-dependent kinase inhibitor 1. (164 aa)
BAK1Bcl-2 homologous antagonist/killer isoform X1. (239 aa)
BLMBloom syndrome protein isoform X1. (1447 aa)
SIRT1NAD-dependent protein deacetylase sirtuin-1 isoform X1. (557 aa)
OPN5Opsin-5; Belongs to the G-protein coupled receptor 1 family. (353 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (816 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3064 aa)
POLHDNA polymerase eta isoform X1. (709 aa)
KDM1ALysine-specific histone demethylase 1A. (730 aa)
WNK3LOW QUALITY PROTEIN: serine/threonine-protein kinase WNK3. (1732 aa)
TMEM161ATransmembrane protein 161A isoform X1. (479 aa)
PBKLymphokine-activated killer T-cell-originated protein kinase. (323 aa)
BCL10B-cell lymphoma/leukemia 10. (233 aa)
NEDD4E3 ubiquitin-protein ligase NEDD4 isoform X1. (1319 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
ERCC1DNA excision repair protein ERCC-1 isoform X2. (432 aa)
CERS1Ceramide synthase 1. (239 aa)
BBC3LOW QUALITY PROTEIN: bcl-2-binding component 3. (201 aa)
POLD1DNA polymerase. (1107 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa)
CHEK2Serine/threonine-protein kinase Chk2. (544 aa)
DHX36ATP-dependent RNA helicase DHX36. (1015 aa)
ATRSerine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family. (2645 aa)
MAP3K14Mitogen-activated protein kinase kinase kinase 14. (961 aa)
TLK2Serine/threonine-protein kinase tousled-like 2 isoform X1. (750 aa)
METTL3N6-adenosine-methyltransferase catalytic subunit; Belongs to the MT-A70-like family. (580 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
LOC112410884LOW QUALITY PROTEIN: peptidyl-prolyl cis-trans isomerase D-like. (370 aa)
PRAP1Proline-rich acidic protein 1. (150 aa)
BNIP3BCL2/adenovirus E1B 19 kDa protein-interacting protein 3. (196 aa)
POLD3DNA polymerase delta subunit 3. (464 aa)
XRCC5X-ray repair cross-complementing protein 5 isoform X1. (766 aa)
XPCDNA repair protein complementing XP-C cells. (959 aa)
CUNH9orf116UPF0691 protein C9orf116 homolog isoform X1. (143 aa)
PIEZO2Piezo-type mechanosensitive ion channel component. (2709 aa)
OPN1SWShort-wave-sensitive opsin 1. (343 aa)
CRB1Protein crumbs homolog 1. (1157 aa)
COPS9COP9 signalosome complex subunit 9. (57 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
BABAM2BRISC and BRCA1-A complex member 2 isoform X1. (402 aa)
SFRP1Secreted frizzled-related protein 1. (296 aa)
WRNWerner syndrome ATP-dependent helicase isoform X1. (1445 aa)
FIGNL1Fidgetin-like protein 1; Belongs to the AAA ATPase family. (677 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1672 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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