STRINGSTRING
XRCC5 XRCC5 LOC112407988 LOC112407988 LOC112407979 LOC112407979 NIPBL NIPBL NUCKS1 NUCKS1 XRCC6 XRCC6 CCND2 CCND2 SFRP1 SFRP1 PRAP1 PRAP1 ATM ATM
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
XRCC5X-ray repair cross-complementing protein 5 isoform X1. (766 aa)
LOC112407988Secreted frizzled-related protein 2. (294 aa)
LOC112407979Secreted frizzled-related protein 2-like. (105 aa)
NIPBLNipped-B protein. (2803 aa)
NUCKS1Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1. (137 aa)
XRCC6X-ray repair cross-complementing protein 6 isoform X1. (654 aa)
CCND2G1/S-specific cyclin-D2; Belongs to the cyclin family. (289 aa)
SFRP1Secreted frizzled-related protein 1. (296 aa)
PRAP1Proline-rich acidic protein 1. (150 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3064 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
Server load: low (24%) [HD]