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| | RUVBL2 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa) |
| | FRZB | Secreted frizzled-related protein 3. (325 aa) |
| | MESP1 | Mesoderm posterior protein 1. (265 aa) |
| | LIMD1 | LIM domain-containing protein 1. (669 aa) |
| | BICC1 | Protein bicaudal C homolog 1 isoform X1. (974 aa) |
| | FERMT1 | Fermitin family homolog 1 isoform X1. (677 aa) |
| | BMP2 | Bone morphogenetic protein 2 isoform X1. (395 aa) |
| | TMEM64 | Transmembrane protein 64 isoform X1. (330 aa) |
| | NPHP4 | Nephrocystin-4. (1063 aa) |
| | AXIN1 | Axin-1 isoform X1. (866 aa) |
| | TNN | tenascin-N. (1296 aa) |
| | CAV1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa) |
| | LOC112407988 | Secreted frizzled-related protein 2. (294 aa) |
| | NOG | Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa) |
| | WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa) |
| | TMEM131L | Transmembrane protein 131-like isoform X1. (1537 aa) |
| | LOC112407979 | Secreted frizzled-related protein 2-like. (105 aa) |
| | TPBG | Trophoblast glycoprotein. (728 aa) |
| | LOC112407021 | Nephrocystin-4-like. (408 aa) |
| | DKK3 | Dickkopf-related protein 3. (349 aa) |
| | STK3 | Serine/threonine-protein kinase 3. (491 aa) |
| | TCF7L2 | Transcription factor 7-like 2 isoform X1. (510 aa) |
| | FOXO3 | Forkhead box protein O3. (672 aa) |
| | DAB2 | Disabled homolog 2 isoform X1. (769 aa) |
| | CTNNB1 | Catenin beta-1. (781 aa) |
| | LATS2 | Serine/threonine-protein kinase LATS2. (805 aa) |
| | AMER2 | APC membrane recruitment protein 2. (357 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (531 aa) |
| | DKK2 | Dickkopf-related protein 2. (259 aa) |
| | AMFR | E3 ubiquitin-protein ligase AMFR. (647 aa) |
| | SCYL2 | SCY1-like protein 2 isoform X1. (928 aa) |
| | DRAXIN | Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. (350 aa) |
| | SOX13 | Transcription factor SOX-13. (592 aa) |
| | CTNNBIP1 | Beta-catenin-interacting protein 1. (81 aa) |
| | G3BP1 | Ras GTPase-activating protein-binding protein 1. (465 aa) |
| | AMER1 | APC membrane recruitment protein 1. (1129 aa) |
| | MAD2L2 | Mitotic spindle assembly checkpoint protein MAD2B. (211 aa) |
| | TMEM88 | Transmembrane protein 88. (159 aa) |
| | FRMD8 | FERM domain-containing protein 8 isoform X1. (465 aa) |
| | CTNND1 | Catenin delta-1 isoform X1. (961 aa) |
| | LOC112401545 | LOW QUALITY PROTEIN: serine/threonine-protein kinase 3-like. (375 aa) |
| | SDHAF2 | Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer. (185 aa) |
| | LRP4 | Low-density lipoprotein receptor-related protein 4. (1914 aa) |
| | TLE3 | Transducin-like enhancer protein 3 isoform X1. (772 aa) |
| | CYLD | Ubiquitin carboxyl-terminal hydrolase CYLD isoform X1; Belongs to the peptidase C19 family. (953 aa) |
| | PRKN | E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (465 aa) |
| | LATS1 | Serine/threonine-protein kinase LATS1. (1128 aa) |
| | SFRP1 | Secreted frizzled-related protein 1. (296 aa) |
| | MLLT3 | Protein AF-9 isoform X1. (608 aa) |
| | GPC3 | Glypican-3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (580 aa) |
| | NKD1 | Protein naked cuticle homolog 1 isoform X1. (473 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) |
| | ANKRD6 | Ankyrin repeat domain-containing protein 6. (459 aa) |
| | STK4 | Serine/threonine-protein kinase 4 isoform X1. (487 aa) |
| | DKK4 | LOW QUALITY PROTEIN: dickkopf-related protein 4. (251 aa) |
| | TMEM170B | Transmembrane protein 170B isoform X1. (237 aa) |
| | CHD8 | Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2591 aa) |
| | SOST | Sclerostin. (212 aa) |
| | SOX10 | Transcription factor SOX-10. (468 aa) |
| | NOTUM | Palmitoleoyl-protein carboxylesterase NOTUM. (478 aa) |
| | AXIN2 | Axin-2. (720 aa) |
| | SOX9 | Transcription factor SOX-9. (486 aa) |
| | DKK1 | Dickkopf-related protein 1. (268 aa) |
| | JADE1 | Protein Jade-1 isoform X1. (858 aa) |
| | CTHRC1 | Collagen triple helix repeat-containing protein 1. (244 aa) |
| | FZD6 | Frizzled-6; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa) |
| | SOX17 | LOW QUALITY PROTEIN: transcription factor SOX-17. (207 aa) |
| | RBMS3 | RNA-binding motif, single-stranded-interacting protein 3 isoform X1. (436 aa) |
| | SFRP4 | Secreted frizzled-related protein 4 isoform X1. (346 aa) |
| | MCC | Colorectal mutant cancer protein isoform X1. (829 aa) |
| | APC | Adenomatous polyposis coli protein isoform X1. (2863 aa) |
| | SNAI2 | Zinc finger protein SNAI2. (268 aa) |
| | LOC112397760 | Emerin-like. (176 aa) |
| | HDAC1 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (419 aa) |
| | TLE6 | Transducin-like enhancer protein 6 isoform X1. (516 aa) |
| | PRICKLE1 | Prickle-like protein 1 isoform X1. (874 aa) |
| | AES | Amino-terminal enhancer of split. (136 aa) |
| | ISL1 | Insulin gene enhancer protein ISL-1. (349 aa) |
| | TLE4 | Transducin-like enhancer protein 4 isoform X1. (712 aa) |
| | STK11 | Serine/threonine-protein kinase STK11 isoform X1. (546 aa) |
| | TLE2 | Transducin-like enhancer protein 2. (733 aa) |
| | APC2 | Adenomatous polyposis coli protein 2. (1995 aa) |
| | UBAC2 | Ubiquitin-associated domain-containing protein 2 isoform X1. (345 aa) |
| | SHH | Sonic hedgehog protein. (328 aa) |
| | DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa) |
| | CSNK1A1 | Casein kinase I isoform X1; Belongs to the protein kinase superfamily. (365 aa) |
| | GLI1 | Zinc finger protein GLI1 isoform X1. (1106 aa) |
| | LMBR1L | Protein LMBR1L isoform X1; Belongs to the LIMR family. (520 aa) |
| | PFDN5 | Prefoldin subunit 5. (154 aa) |
| | CCDC88C | Protein Daple isoform X1. (1997 aa) |
| | SFRP5 | Secreted frizzled-related protein 5. (446 aa) |
| | LOC112393457 | Transducin-like enhancer protein 7. (415 aa) |
| | INVS | Inversin isoform X1. (1079 aa) |
| | LZTS2 | Leucine zipper putative tumor suppressor 2; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta- catenin. (664 aa) |
| | GLI3 | Transcriptional activator GLI3. (1587 aa) |
| | GREM1 | Gremlin. (184 aa) |
| | PTPRO | Receptor-type tyrosine-protein phosphatase O isoform X1. (1197 aa) |
| | LOC112391704 | LOW QUALITY PROTEIN: ras GTPase-activating protein-binding protein 1-like. (470 aa) |
| | LOC112390732 | Ankyrin repeat domain-containing protein 6-like. (269 aa) |
| | NKD2 | Protein naked cuticle homolog 2. (598 aa) |
| | DACT1 | Dapper homolog 1. (691 aa) |
| | SHISA3 | Protein shisa-3 homolog. (238 aa) |
| | GSK3A | Glycogen synthase kinase-3 alpha. (320 aa) |
| | DKKL1 | Dickkopf-like protein 1 isoform X1. (235 aa) |
| | SOSTDC1 | Sclerostin domain-containing protein 1. (206 aa) |
| | SIAH2 | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (198 aa) |
| | WWTR1 | WW domain-containing transcription regulator protein 1. (400 aa) |
| | GSK3B | Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa) |
| | OTUD5 | OTU domain-containing protein 5. (447 aa) |
| | RAPGEF1 | Rap guanine nucleotide exchange factor 1. (1094 aa) |
| | LOC112411741 | Transducin-like enhancer protein 1 isoform X1. (780 aa) |
| | NOTCH1 | LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 1. (2633 aa) |
| | CBY1 | Protein chibby homolog 1 isoform X1. (156 aa) |
| | DAB2IP | Disabled homolog 2-interacting protein isoform X1. (1071 aa) |
| | TPBGL | LOW QUALITY PROTEIN: trophoblast glycoprotein-like. (322 aa) |
| | NPHP3 | Nephrocystin-3 isoform X2. (1234 aa) |
| | SLC9A3R1 | Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (366 aa) |
| | FZD4 | Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa) |
| | FUZ | Protein fuzzy homolog isoform X1. (440 aa) |
| | DACT3 | Dapper homolog 3. (281 aa) |
| | KREMEN1 | Kremen protein 1. (348 aa) |
| | PTPRU | Receptor-type tyrosine-protein phosphatase U isoform X1. (1463 aa) |
