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| | ERBB3 | Receptor tyrosine-protein kinase erbB-3 isoform X1. (1337 aa) |
| | BCL2L10 | LOW QUALITY PROTEIN: bcl-2-like protein 10. (262 aa) |
| | MSH2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (934 aa) |
| | CTNNB1 | Catenin beta-1. (781 aa) |
| | DAPK1 | Death-associated protein kinase 1 isoform X1. (1440 aa) |
| | TOPORS | E3 ubiquitin-protein ligase Topors isoform X1. (1044 aa) |
| | MSH6 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1361 aa) |
| | LOC112405151 | Cytochrome P450 1B1; Belongs to the cytochrome P450 family. (543 aa) |
| | NFATC4 | Nuclear factor of activated T-cells, cytoplasmic 4 isoform X1. (831 aa) |
| | FLCN | Folliculin isoform X1. (576 aa) |
| | BCL2 | Apoptosis regulator Bcl-2 isoform X1. (233 aa) |
| | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa) |
| | CTNNA1 | Catenin alpha-1. (906 aa) |
| | DELE1 | Death ligand signal enhancer isoform X1. (540 aa) |
| | SHISA5 | Protein shisa-5 isoform X1. (239 aa) |
| | IL7 | Interleukin-7 isoform X1. (226 aa) |
| | IKBKE | Inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1. (773 aa) |
| | ITGAV | Integrin alpha-V; Belongs to the integrin alpha chain family. (985 aa) |
| | IVNS1ABP | Influenza virus NS1A-binding protein. (642 aa) |
| | PTGIS | Prostacyclin synthase isoform X1; Belongs to the cytochrome P450 family. (701 aa) |
| | LOC112403632 | Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (221 aa) |
| | LOC112402947 | Death-inducer obliterator 1-like. (696 aa) |
| | TP53BP2 | Apoptosis-stimulating of p53 protein 2. (1007 aa) |
| | G0S2 | G0/G1 switch protein 2. (103 aa) |
| | CEBPB | CCAAT/enhancer-binding protein. (346 aa) |
| | EPHA2 | Ephrin type-A receptor 2. (975 aa) |
| | RNF186 | RING finger protein 186. (226 aa) |
| | DIDO1 | Death-inducer obliterator 1. (1221 aa) |
| | ANXA6 | Annexin. (673 aa) |
| | TMEM109 | Transmembrane protein 109 isoform X1. (254 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (211 aa) |
| | BAD | Bcl2-associated agonist of cell death. (168 aa) |
| | CASP9 | Caspase-9; Belongs to the peptidase C14A family. (442 aa) |
| | UBE4B | Ubiquitin conjugation factor E4 B isoform X2. (1360 aa) |
| | TNFRSF1B | Tumor necrosis factor receptor superfamily member 1B. (454 aa) |
| | LGALS12 | Galectin. (314 aa) |
| | LOC112402267 | Tumor necrosis factor receptor superfamily member 22-like. (321 aa) |
| | PHLDA3 | Pleckstrin homology-like domain family A member 3. (123 aa) |
| | HRAS | GTPase HRas isoform X1. (189 aa) |
| | CASP8AP2 | CASP8-associated protein 2 isoform X1. (1973 aa) |
| | PIDD1 | P53-induced death domain-containing protein 1. (914 aa) |
| | TNFSF12 | Tumor necrosis factor ligand superfamily member 12; Belongs to the tumor necrosis factor family. (248 aa) |
| | CD5 | T-cell surface glycoprotein CD5. (496 aa) |
| | LOC112401545 | LOW QUALITY PROTEIN: serine/threonine-protein kinase 3-like. (375 aa) |
| | RAD9A | Cell cycle checkpoint control protein; Belongs to the rad9 family. (420 aa) |
| | TNFRSF10A | Tumor necrosis factor receptor superfamily member 10A isoform X1. (452 aa) |
| | UACA | Uveal autoantigen with coiled-coil domains and ankyrin repeats isoform X1. (1415 aa) |
| | LOC112401122 | Huntingtin-interacting protein 1. (914 aa) |
| | DNM1L | Dynamin-1-like protein isoform X2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (749 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2709 aa) |
| | LOC112401433 | Tumor necrosis factor receptor superfamily member 10B-like. (456 aa) |
| | NOX1 | LOW QUALITY PROTEIN: NADPH oxidase 1. (569 aa) |
| | EYA2 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (537 aa) |
| | LOC112400428 | LOW QUALITY PROTEIN: catenin alpha-1-like. (875 aa) |
| | STK4 | Serine/threonine-protein kinase 4 isoform X1. (487 aa) |
| | FHIT | Bis(5'-adenosyl)-triphosphatase. (175 aa) |
| | LOC112399406 | Apoptosis-associated speck-like protein containing a CARD isoform X1. (191 aa) |
| | ERN2 | Serine/threonine-protein kinase/endoribonuclease IRE2 isoform X1. (927 aa) |
| | NUPR1 | Nuclear protein 1. (82 aa) |
| | HIP1 | LOW QUALITY PROTEIN: huntingtin-interacting protein 1. (106 aa) |
| | FIS1 | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa) |
| | UMOD | Uromodulin. (643 aa) |
| | ITPRIPL2 | Inositol 1,4,5-trisphosphate receptor-interacting protein-like 2. (532 aa) |
| | PCGF2 | Polycomb group RING finger protein 2 isoform X1. (389 aa) |
| | FAS | Tumor necrosis factor receptor superfamily member 6 isoform X1. (334 aa) |
| | ATP2A1 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (973 aa) |
| | LOC112399310 | Apoptosis-associated speck-like protein containing a CARD isoform X1. (195 aa) |
| | PDK2 | Protein-serine/threonine kinase. (407 aa) |
| | BCL2L1 | Bcl-2-like protein 1 isoform X1. (233 aa) |
| | IL1A | Interleukin-1; Belongs to the IL-1 family. (265 aa) |
| | BCL2L11 | Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (196 aa) |
| | E2F1 | Transcription factor E2F1. (360 aa) |
| | HIPK2 | Homeodomain-interacting protein kinase 2. (1027 aa) |
| | LOC112398305 | Bcl-2-related protein A1. (175 aa) |
| | PRKDC | DNA-dependent protein kinase catalytic subunit isoform X1; Belongs to the PI3/PI4-kinase family. (4129 aa) |
| | CASP6 | Caspase-6 isoform X1; Belongs to the peptidase C14A family. (294 aa) |
| | PDCD10 | Programmed cell death protein 10. (212 aa) |
| | TRIB3 | Tribbles homolog 3. (357 aa) |
| | RB1CC1 | RB1-inducible coiled-coil protein 1 isoform X1. (1658 aa) |
| | BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1870 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa) |
| | TFPT | TCF3 fusion partner isoform X1. (253 aa) |
| | SORT1 | Sortilin. (694 aa) |
| | ZNF622 | Zinc finger protein 622. (466 aa) |
| | LOC112396666 | Transmembrane protein 117. (203 aa) |
| | SAMD8 | Sphingomyelin synthase-related protein 1 isoform X1. (615 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | DDIT4 | DNA damage-inducible transcript 4 protein. (229 aa) |
| | LOC112396076 | ATP-dependent RNA helicase DDX3X-like; Belongs to the DEAD box helicase family. (656 aa) |
| | TM2D1 | TM2 domain-containing protein 1 isoform X1. (213 aa) |
| | ERCC6 | DNA excision repair protein ERCC-6. (1485 aa) |
| | STK11 | Serine/threonine-protein kinase STK11 isoform X1. (546 aa) |
| | EYA1 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (589 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | SHH | Sonic hedgehog protein. (328 aa) |
| | CD28 | T-cell-specific surface glycoprotein CD28. (265 aa) |
| | ATF4 | Cyclic AMP-dependent transcription factor ATF-4. (350 aa) |
| | PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (468 aa) |
| | BAG6 | Large proline-rich protein BAG6 isoform X1. (1164 aa) |
| | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1. (667 aa) |
| | LOC112395324 | LOW QUALITY PROTEIN: keratin, type II cytoskeletal 8-like; Belongs to the intermediate filament family. (504 aa) |
| | DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa) |
| | EP300 | Histone acetyltransferase p300. (2399 aa) |
| | COL2A1 | Collagen alpha-1(II) chain. (1487 aa) |
| | PAWR | PRKC apoptosis WT1 regulator protein. (183 aa) |
| | SENP1 | Sentrin-specific protease 1 isoform X1. (690 aa) |
| | LOC112394217 | Transmembrane protein 117-like. (261 aa) |
| | SNW1 | SNW domain-containing protein 1. (536 aa) |
| | KRT8 | Keratin, type II cytoskeletal 8; Belongs to the intermediate filament family. (489 aa) |
| | QRICH1 | Glutamine-rich protein 1. (780 aa) |
| | DYRK2 | Dual specificity tyrosine-phosphorylation-regulated kinase 2 isoform X1. (537 aa) |
| | RNF41 | E3 ubiquitin-protein ligase NRDP1 isoform X1. (317 aa) |
| | FAIM2 | Protein lifeguard 2; Belongs to the BI1 family. (316 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa) |
| | NF1 | Neurofibromin isoform X1. (2841 aa) |
| | ACVR1B | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (453 aa) |
| | INCA1 | Protein INCA1. (247 aa) |
| | KRT18 | Keratin, type I cytoskeletal 18; Belongs to the intermediate filament family. (429 aa) |
| | RHOT1 | Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (704 aa) |
| | MYBBP1A | LOW QUALITY PROTEIN: myb-binding protein 1A. (1407 aa) |
| | ERO1A | ERO1-like protein alpha. (468 aa) |
| | HIC1 | Hypermethylated in cancer 1 protein. (757 aa) |
| | DAPL1 | Death-associated protein-like 1. (107 aa) |
| | ATAD5 | ATPase family AAA domain-containing protein 5. (1898 aa) |
| | ITPRIP | Inositol 1,4,5-trisphosphate receptor-interacting protein. (556 aa) |
| | SKIL | LOW QUALITY PROTEIN: ski-like protein. (664 aa) |
| | WWOX | WW domain-containing oxidoreductase isoform X1. (417 aa) |
| | NOL3 | Nucleolar protein 3. (202 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (376 aa) |
| | DDX47 | Probable ATP-dependent RNA helicase DDX47; Belongs to the DEAD box helicase family. (455 aa) |
| | TNFRSF1A | Tumor necrosis factor receptor superfamily member 1A. (445 aa) |
| | TRADD | Tumor necrosis factor receptor type 1-associated DEATH domain protein. (311 aa) |
| | IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (222 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa) |
| | ATP2A3 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1057 aa) |
| | CD27 | CD27 antigen. (251 aa) |
| | FGFR3 | Fibroblast growth factor receptor. (804 aa) |
| | INHBA | Inhibin beta A chain. (474 aa) |
| | FASLG | Tumor necrosis factor ligand superfamily member 6; Belongs to the tumor necrosis factor family. (262 aa) |
| | AEN | Apoptosis-enhancing nuclease. (316 aa) |
| | PDK1 | Protein-serine/threonine kinase. (378 aa) |
| | PDIA3 | Protein disulfide-isomerase. (505 aa) |
| | ELL3 | RNA polymerase II elongation factor ELL3 isoform X1. (354 aa) |
| | CHAC1 | Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (221 aa) |
| | CRADD | Death domain-containing protein CRADD isoform X1. (199 aa) |
| | GGCT | Gamma-glutamylcyclotransferase isoform X1. (209 aa) |
| | FOXO3 | Forkhead box protein O3. (672 aa) |
| | STK25 | Serine/threonine-protein kinase 25. (458 aa) |
| | BRCA2 | Breast cancer type 2 susceptibility protein. (3435 aa) |
| | PMAIP1 | Phorbol-12-myristate-13-acetate-induced protein 1. (54 aa) |
| | PDX1 | Pancreas/duodenum homeobox protein 1. (289 aa) |
| | JMY | Junction-mediating and -regulatory protein. (988 aa) |
| | LOC112406956 | LOW QUALITY PROTEIN: voltage-dependent anion-selective channel protein 2-like. (296 aa) |
| | BAG3 | BAG family molecular chaperone regulator 3. (577 aa) |
| | RAF1 | RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa) |
| | NBN | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (727 aa) |
| | STK3 | Serine/threonine-protein kinase 3. (491 aa) |
| | RRP8 | Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] (468 aa) |
| | USP47 | Ubiquitin carboxyl-terminal hydrolase 47 isoform X1; Belongs to the peptidase C19 family. (1355 aa) |
| | DEDD | Death effector domain-containing protein. (318 aa) |
| | CASP8 | Caspase-8 isoform X1; Belongs to the peptidase C14A family. (497 aa) |
| | CFLAR | CASP8 and FADD-like apoptosis regulator isoform X1; Belongs to the peptidase C14A family. (532 aa) |
| | LOC112408296 | Interferon alpha-inducible protein 27, mitochondrial-like. (182 aa) |
| | CASP10 | Caspase-10; Belongs to the peptidase C14A family. (517 aa) |
| | CASP2 | Caspase-2 isoform X1; Belongs to the peptidase C14A family. (452 aa) |
| | APOPT1 | Apoptogenic protein 1, mitochondrial isoform X1. (233 aa) |
| | DIABLO | Diablo homolog, mitochondrial. (237 aa) |
| | CAV1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa) |
| | P2RX7 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa) |
| | P2RX4 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (388 aa) |
| | AIFM1 | Apoptosis-inducing factor 1, mitochondrial. (613 aa) |
| | GSKIP | GSK3B-interacting protein isoform X1. (152 aa) |
| | APAF1 | Apoptotic protease-activating factor 1 isoform X1. (1301 aa) |
| | MAP3K5 | Mitogen-activated protein kinase kinase kinase 5 isoform X2. (1366 aa) |
| | PDPK1 | 3-phosphoinositide-dependent protein kinase 1 isoform X1. (531 aa) |
| | LOC112408777 | Interferon alpha-inducible protein 27-like protein 2 isoform X1. (207 aa) |
| | INHBB | Inhibin beta B chain. (345 aa) |
| | PPP1R13B | Apoptosis-stimulating of p53 protein 1 isoform X2. (1072 aa) |
| | RHOT2 | Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (644 aa) |
| | DDX3X | ATP-dependent RNA helicase DDX3X isoform X1; Belongs to the DEAD box helicase family. (662 aa) |
| | TLR3 | Toll-like receptor 3 isoform X2; Belongs to the Toll-like receptor family. (956 aa) |
| | CASP3 | Caspase-3 isoform X1; Belongs to the peptidase C14A family. (307 aa) |
| | BDKRB2 | B2 bradykinin receptor; Belongs to the G-protein coupled receptor 1 family. (360 aa) |
| | YAP1 | Transcriptional coactivator YAP1. (416 aa) |
| | TP73 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (718 aa) |
| | CDIP1 | Cell death-inducing p53-target protein 1. (238 aa) |
| | POU4F1 | POU domain protein. (320 aa) |
| | BOK | Bcl-2-related ovarian killer protein. (246 aa) |
| | ERN1 | Serine/threonine-protein kinase/endoribonuclease IRE1. (858 aa) |
| | SIVA1 | Apoptosis regulatory protein Siva; Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl- x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis. (175 aa) |
| | LOC112409859 | LOW QUALITY PROTEIN: interferon alpha-inducible protein 27-like protein 2A. (152 aa) |
| | DDX5 | Probable ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family. (614 aa) |
| | PML | Protein PML isoform X1. (965 aa) |
| | PARP2 | Poly [ADP-ribose] polymerase. (563 aa) |
| | BNIP3 | BCL2/adenovirus E1B 19 kDa protein-interacting protein 3. (196 aa) |
| | DAB2IP | Disabled homolog 2-interacting protein isoform X1. (1071 aa) |
| | MLLT11 | Protein AF1q. (90 aa) |
| | MAEL | Protein maelstrom homolog isoform X1. (434 aa) |
| | RTL10 | Protein Bop. (380 aa) |
| | PPM1F | Protein phosphatase 1F isoform X1. (433 aa) |
| | MELK | Non-specific serine/threonine protein kinase. (650 aa) |
| | ADORA2A | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (408 aa) |
| | PTPRC | Receptor-type tyrosine-protein phosphatase C isoform X1. (1258 aa) |
| | HIPK1 | Homeodomain-interacting protein kinase 1 isoform X1. (1210 aa) |
| | NGF | Beta-nerve growth factor; Belongs to the NGF-beta family. (241 aa) |
| | SFRP1 | Secreted frizzled-related protein 1. (296 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | HTRA2 | Serine protease HTRA2, mitochondrial. (458 aa) |
| | MCL1 | Induced myeloid leukemia cell differentiation protein Mcl-1. (351 aa) |
| | POLB | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (328 aa) |
| | PPARD | Peroxisome proliferator-activated receptor delta. (441 aa) |
| | LOC112413803 | Polycomb complex protein BMI-1. (326 aa) |
| | CDKN1A | Cyclin-dependent kinase inhibitor 1. (164 aa) |
| | BAK1 | Bcl-2 homologous antagonist/killer isoform X1. (239 aa) |
| | LOC112413460 | Apoptosis-stimulating of p53 protein 2-like. (124 aa) |
| | SGPL1 | Sphingosine-1-phosphate lyase 1. (568 aa) |
| | SIRT1 | NAD-dependent protein deacetylase sirtuin-1 isoform X1. (557 aa) |
| | ZNF385B | Zinc finger protein 385B isoform X1. (539 aa) |
| | SFN | 14-3-3 protein sigma; Belongs to the 14-3-3 family. (248 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3064 aa) |
| | DAXX | Death domain-associated protein 6. (789 aa) |
| | DAP | Death-associated protein 1. (102 aa) |
| | BNIP3L | BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like isoform X1. (218 aa) |
| | E2F2 | Transcription factor E2F2 isoform X1. (437 aa) |
| | NANOS3 | Nanos homolog 3; Belongs to the nanos family. (175 aa) |
| | YJEFN3 | yjeF N-terminal domain-containing protein 3. (249 aa) |
| | NDUFA13 | LOW QUALITY PROTEIN: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13. (164 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa) |
| | TIMM50 | Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (399 aa) |
| | BCL3 | B-cell lymphoma 3 protein. (358 aa) |
| | GSK3A | Glycogen synthase kinase-3 alpha. (320 aa) |
| | TP63 | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa) |
| | DEDD2 | DNA-binding death effector domain-containing protein 2 isoform X1. (323 aa) |
| | BBC3 | LOW QUALITY PROTEIN: bcl-2-binding component 3. (201 aa) |
| | CHEK2 | Serine/threonine-protein kinase Chk2. (544 aa) |
| | LOC112415742 | Caspase-13 isoform X1; Belongs to the peptidase C14A family. (377 aa) |
| | CASP1 | Caspase-1; Belongs to the peptidase C14A family. (404 aa) |
| | GSK3B | Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa) |
| | BAX | Apoptosis regulator BAX. (192 aa) |
| | LOC112415739 | LOW QUALITY PROTEIN: caspase-12-like; Belongs to the peptidase C14A family. (337 aa) |
