STRINGSTRING
NODAL NODAL CALR CALR SYDE1 SYDE1 ACVR1B ACVR1B C1QBP C1QBP ARHGDIB ARHGDIB LOC112392024 LOC112392024 ACVR1C ACVR1C APELA APELA LOC112395837 LOC112395837 AGO2 AGO2 YTHDF3 YTHDF3 TIMP1 TIMP1 GJA1 GJA1 SMURF2 SMURF2 ITGB3 ITGB3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NODALNodal homolog. (348 aa)
CALRCalreticulin. (417 aa)
SYDE1Rho GTPase-activating protein SYDE1 isoform X1. (814 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (453 aa)
C1QBPComplement component 1 Q subcomponent-binding protein, mitochondrial. (278 aa)
ARHGDIBRho GDP-dissociation inhibitor 2. (199 aa)
LOC112392024YTH domain-containing family protein 3-like. (292 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
APELAApelin receptor early endogenous ligand. (54 aa)
LOC112395837LOW QUALITY PROTEIN: calreticulin-like. (540 aa)
AGO2Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (865 aa)
YTHDF3YTH domain-containing family protein 3. (529 aa)
TIMP1Metalloproteinase inhibitor 1. (260 aa)
GJA1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (381 aa)
SMURF2E3 ubiquitin-protein ligase. (738 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (789 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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