19 items (Neophocaena asiaeorientalis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CHD6	chromodomain-helicase-DNA-binding protein 6. (2720 aa)
	CARF	Calcium-responsive transcription factor isoform X1. (721 aa)
	ATF4	Cyclic AMP-dependent transcription factor ATF-4. (350 aa)
	EP300	Histone acetyltransferase p300. (2399 aa)
	SMAD1	Mothers against decapentaplegic homolog. (465 aa)
	NFE2L2	Nuclear factor erythroid 2-related factor 2 isoform X1. (622 aa)
	ATF2	Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa)
	NOTCH1	LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 1. (2633 aa)
	XBP1	LOW QUALITY PROTEIN: X-box-binding protein 1. (379 aa)
	SESN2	Sestrin-2. (471 aa)
	DLX5	Homeobox protein DLX-5. (289 aa)
	RUNX2	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (408 aa)
	BMP2	Bone morphogenetic protein 2 isoform X1. (395 aa)
	CREB3	Cyclic AMP-responsive element-binding protein 3. (371 aa)
	JUN	LOW QUALITY PROTEIN: transcription factor AP-1; Belongs to the bZIP family. (284 aa)
	SMAD5	Mothers against decapentaplegic homolog. (465 aa)
	RELA	Transcription factor p65. (562 aa)
	HIF1A	Hypoxia-inducible factor 1-alpha. (823 aa)
	LOC112400027	Recombining binding protein suppressor of hairless isoform X1. (487 aa)

Your Current Organism:

Neophocaena asiaeorientalis

NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATF2	ATF4	A0A341AHM6	A0A341AVS7	Cyclic AMP-dependent transcription factor ATF-2 isoform X1.	Cyclic AMP-dependent transcription factor ATF-4.	0.911
ATF2	CREB3	A0A341AHM6	A0A341CVI4	Cyclic AMP-dependent transcription factor ATF-2 isoform X1.	Cyclic AMP-responsive element-binding protein 3.	0.941
ATF2	EP300	A0A341AHM6	A0A341AU91	Cyclic AMP-dependent transcription factor ATF-2 isoform X1.	Histone acetyltransferase p300.	0.950
ATF2	JUN	A0A341AHM6	A0A341CB63	Cyclic AMP-dependent transcription factor ATF-2 isoform X1.	LOW QUALITY PROTEIN: transcription factor AP-1; Belongs to the bZIP family.	0.997
ATF4	ATF2	A0A341AVS7	A0A341AHM6	Cyclic AMP-dependent transcription factor ATF-4.	Cyclic AMP-dependent transcription factor ATF-2 isoform X1.	0.911
ATF4	CREB3	A0A341AVS7	A0A341CVI4	Cyclic AMP-dependent transcription factor ATF-4.	Cyclic AMP-responsive element-binding protein 3.	0.896
ATF4	EP300	A0A341AVS7	A0A341AU91	Cyclic AMP-dependent transcription factor ATF-4.	Histone acetyltransferase p300.	0.958
ATF4	JUN	A0A341AVS7	A0A341CB63	Cyclic AMP-dependent transcription factor ATF-4.	LOW QUALITY PROTEIN: transcription factor AP-1; Belongs to the bZIP family.	0.708
ATF4	NFE2L2	A0A341AVS7	A0A341AHP2	Cyclic AMP-dependent transcription factor ATF-4.	Nuclear factor erythroid 2-related factor 2 isoform X1.	0.551
ATF4	RUNX2	A0A341AVS7	A0A341D3Q3	Cyclic AMP-dependent transcription factor ATF-4.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.599
ATF4	SESN2	A0A341AVS7	A0A341D7D1	Cyclic AMP-dependent transcription factor ATF-4.	Sestrin-2.	0.410
ATF4	XBP1	A0A341AVS7	A0A341DCI1	Cyclic AMP-dependent transcription factor ATF-4.	LOW QUALITY PROTEIN: X-box-binding protein 1.	0.808
BMP2	DLX5	A0A341D1S7	A0A341D767	Bone morphogenetic protein 2 isoform X1.	Homeobox protein DLX-5.	0.701
BMP2	RUNX2	A0A341D1S7	A0A341D3Q3	Bone morphogenetic protein 2 isoform X1.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.832
BMP2	SMAD1	A0A341D1S7	A0A341ARX3	Bone morphogenetic protein 2 isoform X1.	Mothers against decapentaplegic homolog.	0.871
BMP2	SMAD5	A0A341D1S7	A0A341C0M5	Bone morphogenetic protein 2 isoform X1.	Mothers against decapentaplegic homolog.	0.845
CHD6	EP300	A0A341B941	A0A341AU91	chromodomain-helicase-DNA-binding protein 6.	Histone acetyltransferase p300.	0.496
CREB3	ATF2	A0A341CVI4	A0A341AHM6	Cyclic AMP-responsive element-binding protein 3.	Cyclic AMP-dependent transcription factor ATF-2 isoform X1.	0.941
CREB3	ATF4	A0A341CVI4	A0A341AVS7	Cyclic AMP-responsive element-binding protein 3.	Cyclic AMP-dependent transcription factor ATF-4.	0.896
CREB3	EP300	A0A341CVI4	A0A341AU91	Cyclic AMP-responsive element-binding protein 3.	Histone acetyltransferase p300.	0.902