STRINGSTRING
RSPO4 RSPO4 NDNF NDNF TKTL1 TKTL1 LOC112399212 LOC112399212 THBS2 THBS2 FGF2 FGF2 LRPAP1 LRPAP1 PTPRF PTPRF OGDH OGDH PTPRS PTPRS FGFRL1 FGFRL1 ANXA5 ANXA5 ZCCHC4 ZCCHC4 PCOLCE PCOLCE TKT TKT FGFR4 FGFR4 NAT6 NAT6 COL5A3 COL5A3 MMACHC MMACHC LRTM1 LRTM1 ADGRG1 ADGRG1 HACL1 HACL1 PCIF1 PCIF1 APOB APOB WISP2 WISP2 COLQ COLQ HDGF HDGF VEGFB VEGFB HSD17B12 HSD17B12 THBS3 THBS3 EFEMP2 EFEMP2 MDK MDK AMT AMT LTBP2 LTBP2 ALDH6A1 ALDH6A1 PODN PODN RSPO1 RSPO1 ACOT11 ACOT11 LRRC3B LRRC3B NRP2 NRP2 GPNMB GPNMB CUNH6orf15 CUNH6orf15 MPIG6B MPIG6B SUV39H2 SUV39H2 TNXB TNXB ECI2 ECI2 LOC112396312 LOC112396312 OGDHL OGDHL AZU1 AZU1 FBN1 FBN1 SCP2 SCP2 SMOC1 SMOC1 FGFBP3 FGFBP3 WISP1 WISP1 FGF10 FGF10 NOV NOV CDON CDON COL25A1 COL25A1 WISP3 WISP3 LOC112397547 LOC112397547 SLIT2 SLIT2 LOC112397818 LOC112397818 PTN PTN LRRC3C LRRC3C PCSK6 PCSK6 GSS GSS SELP SELP MSTN MSTN ADAMTS1 ADAMTS1 PRMT8 PRMT8 THBS1 THBS1 APP APP ADAMTS5 ADAMTS5 ECM2 ECM2 IMPG1 IMPG1 DPYSL3 DPYSL3 LIPI LIPI ALK ALK ACADVL ACADVL F2 F2 KMT5B KMT5B GLRA1 GLRA1 ANXA6 ANXA6 ACBD7 ACBD7 PRELP PRELP SETD6 SETD6 BMPER BMPER LTF LTF CHST15 CHST15 DBT DBT APOA5 APOA5 N6AMT1 N6AMT1 HBEGF HBEGF LPL LPL SLIT3 SLIT3 ACBD3 ACBD3 PANK3 PANK3 CXCL8 CXCL8 CXCL10 CXCL10 PTCH1 PTCH1 LOC112405696 LOC112405696 CXCL11 CXCL11 PPBP PPBP CXCL13 CXCL13 METTL5 METTL5 AOC1 AOC1 KMT5C KMT5C POSTN POSTN ACOT12 ACOT12 THBS4 THBS4 ACOT7 ACOT7 RSPO2 RSPO2 APLP2 APLP2 TPMT TPMT SMAD4 SMAD4 LIPG LIPG ADAMTS15 ADAMTS15 MPO MPO TPK1 TPK1 EVA1C EVA1C BMT2 BMT2 SERPINC1 SERPINC1 SOAT1 SOAT1 LRRTM4 LRRTM4 ACBD6 ACBD6 LRRC3 LRRC3 RSPO3 RSPO3 CBS CBS IMPG2 IMPG2 CTGF CTGF ABI3BP ABI3BP TSR3 TSR3 NYX NYX F11 F11 CEP104 CEP104 ACBD4 ACBD4 APOH APOH SOST SOST RYR2 RYR2 METTL3 METTL3 RNASE4 RNASE4 LIPC LIPC METTL17 METTL17 TMEM184B TMEM184B PTGES PTGES COL5A1 COL5A1 FN1 FN1 LANCL1 LANCL1 AAMP AAMP TMEM184A TMEM184A PTGES2 PTGES2 ACAD9 ACAD9 TWSG1 TWSG1 RTN4R RTN4R SERPINE2 SERPINE2 PTPRC PTPRC NELL1 NELL1 SFRP1 SFRP1 FGFR1 FGFR1 NAV2 NAV2 COL13A1 COL13A1 LRRTM3 LRRTM3 FSTL1 FSTL1 PCOLCE2 PCOLCE2 HRG HRG RCC1 RCC1 CRISPLD1 CRISPLD1 FURIN FURIN GNMT GNMT CLEC3B CLEC3B LOC112413276 LOC112413276 VEGFA VEGFA NRP1 NRP1 REG4 REG4 LRRC70 LRRC70 CYR61 CYR61 GCDH GCDH LIPH LIPH APOE APOE COMP COMP PRMT1 PRMT1 LTK LTK ACBD5 ACBD5 PDCD5 PDCD5 LRTM2 LRTM2 LOC112392060 LOC112392060 DHTKD1 DHTKD1 APLP1 APLP1 CRISPLD2 CRISPLD2 BMP4 BMP4 SLIT1 SLIT1 HPSE2 HPSE2 ZNF207 ZNF207 DBI DBI CCDC80 CCDC80 TKTL2 TKTL2 BOC BOC MGST2 MGST2 NELL2 NELL2 RTN4RL1 RTN4RL1 SOAT2 SOAT2 CHADL CHADL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RSPO4R-spondin-4. (232 aa)
NDNFProtein NDNF. (568 aa)
TKTL1Transketolase-like protein 1. (541 aa)
LOC112399212Sulfotransferase; Belongs to the sulfotransferase 1 family. (316 aa)
THBS2Thrombospondin-2. (1170 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (304 aa)
LRPAP1Alpha-2-macroglobulin receptor-associated protein. (360 aa)
PTPRFReceptor-type tyrosine-protein phosphatase F. (1906 aa)
OGDH2-oxoglutarate dehydrogenase, mitochondrial isoform X3. (1039 aa)
PTPRSLOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase S. (2076 aa)
FGFRL1Fibroblast growth factor receptor-like 1. (483 aa)
ANXA5Annexin. (370 aa)
ZCCHC4Zinc finger CCHC domain-containing protein 4. (513 aa)
PCOLCEProcollagen C-endopeptidase enhancer 1. (455 aa)
TKTTransketolase. (623 aa)
FGFR4Fibroblast growth factor receptor. (810 aa)
NAT6LOW QUALITY PROTEIN: N-acetyltransferase 6. (297 aa)
COL5A3Collagen alpha-3(V) chain. (1732 aa)
MMACHCMethylmalonic aciduria and homocystinuria type C protein isoform X1. (280 aa)
LRTM1Leucine-rich repeat and transmembrane domain-containing protein 1. (405 aa)
ADGRG1Adhesion G-protein coupled receptor G1; Belongs to the G-protein coupled receptor 2 family. (685 aa)
HACL12-hydroxyacyl-CoA lyase 1 isoform X1; Belongs to the TPP enzyme family. (581 aa)
PCIF1Phosphorylated CTD-interacting factor 1. (704 aa)
APOBApolipoprotein B-100. (4565 aa)
WISP2WNT1-inducible-signaling pathway protein 2. (250 aa)
COLQAcetylcholinesterase collagenic tail peptide isoform X1. (448 aa)
HDGFHepatoma-derived growth factor. (205 aa)
VEGFBVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (286 aa)
HSD17B12Very-long-chain 3-oxoacyl-CoA reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (280 aa)
THBS3Thrombospondin-3 isoform X1. (956 aa)
EFEMP2EGF-containing fibulin-like extracellular matrix protein 2. (449 aa)
MDKMidkine isoform X1. (295 aa)
AMTAminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (403 aa)
LTBP2Latent-transforming growth factor beta-binding protein 2. (1772 aa)
ALDH6A1Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial. (479 aa)
PODNPodocan. (607 aa)
RSPO1R-spondin-1. (262 aa)
ACOT11Acyl-coenzyme A thioesterase 11. (560 aa)
LRRC3BLeucine-rich repeat-containing protein 3B. (259 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (931 aa)
GPNMBTransmembrane glycoprotein NMB. (553 aa)
CUNH6orf15Uncharacterized protein C6orf15 homolog. (298 aa)
MPIG6BMegakaryocyte and platelet inhibitory receptor G6b. (248 aa)
SUV39H2Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (277 aa)
TNXBtenascin-X isoform X1. (4137 aa)
ECI2enoyl-CoA delta isomerase 2, mitochondrial isoform X1. (396 aa)
LOC112396312Neutrophil elastase-like; Belongs to the peptidase S1 family. (338 aa)
OGDHL2-oxoglutarate dehydrogenase-like, mitochondrial isoform X1. (1018 aa)
AZU1Azurocidin. (252 aa)
FBN1Fibrillin-1. (2871 aa)
SCP2Non-specific lipid-transfer protein; Belongs to the thiolase-like superfamily. Thiolase family. (547 aa)
SMOC1SPARC-related modular calcium-binding protein 1 isoform X1. (446 aa)
FGFBP3Fibroblast growth factor-binding protein 3. (257 aa)
WISP1WNT1-inducible-signaling pathway protein 1. (281 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
NOVProtein NOV homolog. (359 aa)
CDONCell adhesion molecule-related/down-regulated by oncogenes. (1279 aa)
COL25A1Collagen alpha-1(XXV) chain. (657 aa)
WISP3WNT1-inducible-signaling pathway protein 3. (354 aa)
LOC112397547Slit homolog 2 protein-like. (162 aa)
SLIT2Slit homolog 2 protein. (1286 aa)
LOC112397818Glutathione S-transferase Mu 3. (225 aa)
PTNPleiotrophin isoform X1. (168 aa)
LRRC3CLeucine-rich repeat-containing protein 3C. (273 aa)
PCSK6Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (876 aa)
GSSGlutathione synthetase. (474 aa)
SELPP-selectin isoform X1. (856 aa)
MSTNGrowth/differentiation factor 8. (375 aa)
ADAMTS1A disintegrin and metalloproteinase with thrombospondin motifs 1. (940 aa)
PRMT8Protein arginine N-methyltransferase 8 isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (394 aa)
THBS1Thrombospondin-1. (1170 aa)
APPAmyloid-beta A4 protein isoform X1. (767 aa)
ADAMTS5A disintegrin and metalloproteinase with thrombospondin motifs 5. (947 aa)
ECM2Extracellular matrix protein 2 isoform X1. (695 aa)
IMPG1Interphotoreceptor matrix proteoglycan 1. (767 aa)
DPYSL3Dihydropyrimidinase-related protein 3 isoform X1. (684 aa)
LIPILipase member I. (518 aa)
ALKTyrosine-protein kinase receptor. (1616 aa)
ACADVLVery long-chain specific acyl-CoA dehydrogenase, mitochondrial isoform X1. (655 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (623 aa)
KMT5BHistone-lysine N-methyltransferase KMT5B isoform X1. (883 aa)
GLRA1Glycine receptor subunit alpha-1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (457 aa)
ANXA6Annexin. (673 aa)
ACBD7acyl-CoA-binding domain-containing protein 7. (92 aa)
PRELPProlargin. (381 aa)
SETD6N-lysine methyltransferase SETD6; Protein-lysine N-methyltransferase. Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily. (526 aa)
BMPERBMP-binding endothelial regulator protein. (685 aa)
LTFLactotransferrin isoform X1; Belongs to the transferrin family. (711 aa)
CHST15Carbohydrate sulfotransferase 15. (561 aa)
DBTDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (482 aa)
APOA5Apolipoprotein A-V. (369 aa)
N6AMT1hemK methyltransferase family member 2. (214 aa)
HBEGFProheparin-binding EGF-like growth factor. (208 aa)
LPLLipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (478 aa)
SLIT3Slit homolog 3 protein isoform X2. (1523 aa)
ACBD3Golgi resident protein GCP60 isoform X1. (435 aa)
PANK3Pantothenate kinase 3. (370 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
CXCL10C-X-C motif chemokine. (103 aa)
PTCH1Protein patched homolog 1 isoform X1. (1297 aa)
LOC112405696C-X-C motif chemokine. (112 aa)
CXCL11C-X-C motif chemokine 11 isoform X2. (100 aa)
PPBPC-X-C motif chemokine. (119 aa)
CXCL13C-X-C motif chemokine 13. (109 aa)
METTL5Methyltransferase-like protein 5 isoform X1. (219 aa)
AOC1Amine oxidase. (755 aa)
KMT5CHistone-lysine N-methyltransferase KMT5C. (460 aa)
POSTNPeriostin isoform X4. (809 aa)
ACOT12Acyl-coenzyme A thioesterase 12. (557 aa)
THBS4Thrombospondin-4. (961 aa)
ACOT7Cytosolic acyl coenzyme A thioester hydrolase. (321 aa)
RSPO2R-spondin-2 isoform X1. (249 aa)
APLP2Amyloid-like protein 2 isoform X1. (709 aa)
TPMTThiopurine S-methyltransferase. (245 aa)
SMAD4Mothers against decapentaplegic homolog. (599 aa)
LIPGEndothelial lipase. (504 aa)
ADAMTS15LOW QUALITY PROTEIN: A disintegrin and metalloproteinase with thrombospondin motifs 15. (920 aa)
MPOMyeloperoxidase. (718 aa)
TPK1Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family. (246 aa)
EVA1CProtein eva-1 homolog C isoform X1. (458 aa)
BMT2S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...] (405 aa)
SERPINC1antithrombin-III isoform X1; Belongs to the serpin family. (501 aa)
SOAT1O-acyltransferase. (550 aa)
LRRTM4Leucine-rich repeat transmembrane neuronal protein 4. (590 aa)
ACBD6acyl-CoA-binding domain-containing protein 6. (282 aa)
LRRC3Leucine-rich repeat-containing protein 3. (257 aa)
RSPO3R-spondin-3. (275 aa)
CBSCystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (562 aa)
IMPG2Interphotoreceptor matrix proteoglycan 2 isoform X1. (1281 aa)
CTGFConnective tissue growth factor. (413 aa)
ABI3BPTarget of Nesh-SH3 isoform X2. (1714 aa)
TSR3Probable ribosome biogenesis protein C16orf42 homolog; Probable pre-rRNA processing protein involved in ribosome biogenesis. (309 aa)
NYXNyctalopin. (234 aa)
F11Coagulation factor XI; Belongs to the peptidase S1 family. (638 aa)
CEP104Centrosomal protein of 104 kDa isoform X1. (925 aa)
ACBD4acyl-CoA-binding domain-containing protein 4 isoform X2. (377 aa)
APOHBeta-2-glycoprotein 1 isoform X1. (345 aa)
SOSTSclerostin. (212 aa)
RYR2Ryanodine receptor 2. (4971 aa)
METTL3N6-adenosine-methyltransferase catalytic subunit; Belongs to the MT-A70-like family. (580 aa)
RNASE4Ribonuclease 4; Belongs to the pancreatic ribonuclease family. (147 aa)
LIPCHepatic triacylglycerol lipase. (500 aa)
METTL17Methyltransferase-like protein 17, mitochondrial. (460 aa)
TMEM184BTransmembrane protein 184B. (407 aa)
PTGESProstaglandin E synthase isoform X1. (161 aa)
COL5A1Collagen alpha-1(V) chain. (1652 aa)
FN1Fibronectin isoform X5. (2478 aa)
LANCL1lanC-like protein 1. (399 aa)
AAMPAngio-associated migratory cell protein isoform X1. (435 aa)
TMEM184ATransmembrane protein 184A. (418 aa)
PTGES2Prostaglandin E synthase 2. (372 aa)
ACAD9acyl-CoA dehydrogenase family member 9, mitochondrial. (621 aa)
TWSG1Twisted gastrulation protein homolog 1. (223 aa)
RTN4RReticulon-4 receptor. (564 aa)
SERPINE2Glia-derived nexin; Belongs to the serpin family. (397 aa)
PTPRCReceptor-type tyrosine-protein phosphatase C isoform X1. (1258 aa)
NELL1Protein kinase C-binding protein NELL1 isoform X1. (810 aa)
SFRP1Secreted frizzled-related protein 1. (296 aa)
FGFR1Fibroblast growth factor receptor. (722 aa)
NAV2Neuron navigator 2 isoform X1. (2283 aa)
COL13A1Collagen alpha-1(XIII) chain isoform X1. (655 aa)
LRRTM3Leucine-rich repeat transmembrane neuronal protein 3. (536 aa)
FSTL1Follistatin-related protein 1. (307 aa)
PCOLCE2Procollagen C-endopeptidase enhancer 2 isoform X1. (416 aa)
HRGLOW QUALITY PROTEIN: histidine-rich glycoprotein. (427 aa)
RCC1Regulator of chromosome condensation isoform X2. (457 aa)
CRISPLD1Cysteine-rich secretory protein LCCL domain-containing 1 isoform X1. (500 aa)
FURINFurin; Belongs to the peptidase S8 family. (792 aa)
GNMTGlycine N-methyltransferase. (295 aa)
CLEC3BTetranectin. (202 aa)
LOC112413276C-C motif chemokine. (112 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (632 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (924 aa)
REG4LOW QUALITY PROTEIN: regenerating islet-derived protein 4. (203 aa)
LRRC70Leucine-rich repeat-containing protein 70. (622 aa)
CYR61Protein CYR61. (382 aa)
GCDHglutaryl-CoA dehydrogenase, mitochondrial isoform X1. (448 aa)
LIPHLipase member H. (451 aa)
APOEApolipoprotein E. (316 aa)
COMPCartilage oligomeric matrix protein. (756 aa)
PRMT1Protein arginine N-methyltransferase 1 isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (371 aa)
LTKLOW QUALITY PROTEIN: leukocyte tyrosine kinase receptor. (880 aa)
ACBD5acyl-CoA-binding domain-containing protein 5 isoform X1. (535 aa)
PDCD5Programmed cell death protein 5. (125 aa)
LRTM2Leucine-rich repeat and transmembrane domain-containing protein 2. (370 aa)
LOC112392060Fibroblast growth factor receptor 1-like. (98 aa)
DHTKD1Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial isoform X1. (921 aa)
APLP1Amyloid-like protein 1 isoform X1. (647 aa)
CRISPLD2Cysteine-rich secretory protein LCCL domain-containing 2. (496 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (420 aa)
SLIT1Slit homolog 1 protein. (1514 aa)
HPSE2Inactive heparanase-2 isoform X1. (592 aa)
ZNF207BUB3-interacting and GLEBS motif-containing protein ZNF207 isoform X1. (495 aa)
DBIacyl-CoA-binding protein. (87 aa)
CCDC80Coiled-coil domain-containing protein 80. (951 aa)
TKTL2LOW QUALITY PROTEIN: transketolase-like protein 2. (751 aa)
BOCBrother of CDO isoform X1. (1116 aa)
MGST2LOW QUALITY PROTEIN: microsomal glutathione S-transferase 2. (142 aa)
NELL2Protein kinase C-binding protein NELL2. (817 aa)
RTN4RL1Reticulon-4 receptor-like 1 isoform X1. (457 aa)
SOAT2O-acyltransferase. (539 aa)
CHADLChondroadherin-like protein. (787 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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