STRINGSTRING
HGF HGF FGG FGG FGB FGB ITPRIP ITPRIP FAIM2 FAIM2 LOC112396076 LOC112396076 BRCA1 BRCA1 HMOX1 HMOX1 ITPRIPL2 ITPRIPL2 PARK7 PARK7 FAIM FAIM PEA15 PEA15 RAF1 RAF1 CFLAR CFLAR LOC112407979 LOC112407979 LOC112407988 LOC112407988 RNF34 RNF34 TNFAIP3 TNFAIP3 DDX3X DDX3X TMBIM1 TMBIM1 RFFL RFFL GSK3B GSK3B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HGFHepatocyte growth factor isoform X1; Belongs to the peptidase S1 family. (734 aa)
FGGFibrinogen gamma chain isoform X1. (445 aa)
FGBFibrinogen beta chain isoform X1. (495 aa)
ITPRIPInositol 1,4,5-trisphosphate receptor-interacting protein. (556 aa)
FAIM2Protein lifeguard 2; Belongs to the BI1 family. (316 aa)
LOC112396076ATP-dependent RNA helicase DDX3X-like; Belongs to the DEAD box helicase family. (656 aa)
BRCA1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1870 aa)
HMOX1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (288 aa)
ITPRIPL2Inositol 1,4,5-trisphosphate receptor-interacting protein-like 2. (532 aa)
PARK7Protein/nucleic acid deglycase DJ-1. (189 aa)
FAIMFas apoptotic inhibitory molecule 1. (179 aa)
PEA15Astrocytic phosphoprotein PEA-15. (130 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa)
CFLARCASP8 and FADD-like apoptosis regulator isoform X1; Belongs to the peptidase C14A family. (532 aa)
LOC112407979Secreted frizzled-related protein 2-like. (105 aa)
LOC112407988Secreted frizzled-related protein 2. (294 aa)
RNF34E3 ubiquitin-protein ligase RNF34. (376 aa)
TNFAIP3Tumor necrosis factor alpha-induced protein 3. (785 aa)
DDX3XATP-dependent RNA helicase DDX3X isoform X1; Belongs to the DEAD box helicase family. (662 aa)
TMBIM1Protein lifeguard 3; Belongs to the BI1 family. (308 aa)
RFFLE3 ubiquitin-protein ligase rififylin isoform X1. (393 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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