89 items (Neophocaena asiaeorientalis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SEC24B	Protein transport protein Sec24B isoform X1. (1168 aa)
	SPEF1	Sperm flagellar protein 1 isoform X1. (342 aa)
	NGFR	Tumor necrosis factor receptor superfamily member 16. (427 aa)
	FZD6	Frizzled-6; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa)
	CTHRC1	Collagen triple helix repeat-containing protein 1. (244 aa)
	SP6	Transcription factor Sp6. (375 aa)
	FGF2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (304 aa)
	RYK	Tyrosine-protein kinase RYK. (705 aa)
	SPRY1	Protein sprouty homolog 1. (319 aa)
	HOXB7	Homeobox protein Hox-B7. (217 aa)
	ANKRD6	Ankyrin repeat domain-containing protein 6. (459 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
	NKD1	Protein naked cuticle homolog 1 isoform X1. (473 aa)
	GPC3	Glypican-3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (580 aa)
	MLLT3	Protein AF-9 isoform X1. (608 aa)
	PLEKHA4	Pleckstrin homology domain-containing family A member 4 isoform X1. (781 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
	DVL3	Segment polarity protein dishevelled homolog DVL-3 isoform X1. (716 aa)
	SIX1	Homeobox protein SIX1. (284 aa)
	SIX4	Homeobox protein SIX4. (793 aa)
	FGF7	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
	VANGL2	Vang-like protein. (571 aa)
	BMP7	Bone morphogenetic protein 7. (431 aa)
	AR	Androgen receptor isoform X1. (893 aa)
	HGF	Hepatocyte growth factor isoform X1; Belongs to the peptidase S1 family. (734 aa)
	SIX2	Homeobox protein SIX2 isoform X1. (298 aa)
	FZD3	Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (468 aa)
	CTNNB1	Catenin beta-1. (781 aa)
	DAB2	Disabled homolog 2 isoform X1. (769 aa)
	HOXA11	Homeobox protein Hox-A11. (318 aa)
	GDNF	Glial cell line-derived neurotrophic factor isoform X1. (211 aa)
	TACSTD2	Tumor-associated calcium signal transducer 2. (419 aa)
	LOC112407979	Secreted frizzled-related protein 2-like. (105 aa)
	LOC112408148	LOW QUALITY PROTEIN: tumor-associated calcium signal transducer 2-like. (329 aa)
	WNT11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
	NOG	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
	MKS1	Meckel syndrome type 1 protein isoform X2. (607 aa)
	LHX1	LIM/homeobox protein Lhx1. (406 aa)
	BTBD7	BTB/POZ domain-containing protein 7 isoform X1. (1121 aa)
	MED12	Mediator of RNA polymerase II transcription subunit 12. (2097 aa)
	LOC112407988	Secreted frizzled-related protein 2. (294 aa)
	WNT2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
	AHI1	Jouberin isoform X1. (1178 aa)
	SOX8	Transcription factor SOX-8. (378 aa)
	DVL1	Segment polarity protein dishevelled homolog DVL-1. (706 aa)
	AJAP1	Adherens junction-associated protein 1. (399 aa)
	WNT9B	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (602 aa)
	FZD2	Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (709 aa)
	SOX9	Transcription factor SOX-9. (486 aa)
	PAX9	Paired box protein Pax-9. (342 aa)
	STOX1	Storkhead-box protein 1 isoform X1. (989 aa)
	SAPCD2	Suppressor APC domain-containing protein 2. (307 aa)
	ABL1	Tyrosine-protein kinase. (1148 aa)
	SMO	Smoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (783 aa)
	WNT10A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
	LGR4	Leucine-rich repeat-containing G-protein coupled receptor 4. (1061 aa)
	APCDD1	Protein APCDD1 isoform X1. (524 aa)
	WNT2B	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
	SFRP1	Secreted frizzled-related protein 1. (296 aa)
	BMP2	Bone morphogenetic protein 2 isoform X1. (395 aa)
	PTK7	Inactive tyrosine-protein kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1070 aa)
	PKHD1	Fibrocystin isoform X1. (4079 aa)
	GRHL3	Grainyhead-like protein 3 homolog. (602 aa)
	MESP1	Mesoderm posterior protein 1. (265 aa)
	RUNX2	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (408 aa)
	AGT	Angiotensinogen; Belongs to the serpin family. (477 aa)
	WNT3A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	DVL2	Segment polarity protein dishevelled homolog DVL-2 isoform X1. (785 aa)
	BMPR1A	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
	DACT1	Dapper homolog 1. (691 aa)
	GATA3	Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (444 aa)
	LOC112390732	Ankyrin repeat domain-containing protein 6-like. (269 aa)
	PHB2	Prohibitin. (299 aa)
	GREM1	Gremlin. (184 aa)
	DMRT3	Doublesex- and mab-3-related transcription factor 3. (473 aa)
	FGF8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
	BMP4	Bone morphogenetic protein 4 isoform X1. (420 aa)
	FRS2	Fibroblast growth factor receptor substrate 2. (508 aa)
	HOXC11	LOW QUALITY PROTEIN: homeobox protein Hox-C11. (308 aa)
	CELSR1	Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (2288 aa)
	SHH	Sonic hedgehog protein. (328 aa)
	SULF1	Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (882 aa)
	CITED2	Cbp/p300-interacting transactivator 2. (263 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
	JHY	Jhy protein homolog. (770 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	CSF1	Macrophage colony-stimulating factor 1. (513 aa)
	TNFRSF11B	Tumor necrosis factor receptor superfamily member 11B; Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. (401 aa)
	MSX1	Homeobox protein MSX-1. (303 aa)

Your Current Organism:

Neophocaena asiaeorientalis

NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL1	CTNNB1	A0A341CTZ6	A0A341C5R9	Tyrosine-protein kinase.	Catenin beta-1.	0.706
ABL1	RUNX2	A0A341CTZ6	A0A341D3Q3	Tyrosine-protein kinase.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.482
AGT	TGFB1	A0A341D370	A0A341DAG8	Angiotensinogen; Belongs to the serpin family.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.545
AHI1	MKS1	A0A341CJA0	A0A341CFQ9	Jouberin isoform X1.	Meckel syndrome type 1 protein isoform X2.	0.977
ANKRD6	CELSR1	A0A341BK43	A0A341AR94	Ankyrin repeat domain-containing protein 6.	Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family.	0.570
ANKRD6	DVL1	A0A341BK43	A0A341CMR2	Ankyrin repeat domain-containing protein 6.	Segment polarity protein dishevelled homolog DVL-1.	0.490
ANKRD6	LOC112390732	A0A341BK43	A0A341AD98	Ankyrin repeat domain-containing protein 6.	Ankyrin repeat domain-containing protein 6-like.	0.817
ANKRD6	PTK7	A0A341BK43	A0A341D7Y1	Ankyrin repeat domain-containing protein 6.	Inactive tyrosine-protein kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.542
ANKRD6	VANGL2	A0A341BK43	A0A341BVC4	Ankyrin repeat domain-containing protein 6.	Vang-like protein.	0.463
APCDD1	NKD1	A0A341D0C4	A0A341BKG8	Protein APCDD1 isoform X1.	Protein naked cuticle homolog 1 isoform X1.	0.701
AR	CTNNB1	A0A341BZY8	A0A341C5R9	Androgen receptor isoform X1.	Catenin beta-1.	0.935
AR	RUNX2	A0A341BZY8	A0A341D3Q3	Androgen receptor isoform X1.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.972
BMP2	BMP4	A0A341D1S7	A0A341AL27	Bone morphogenetic protein 2 isoform X1.	Bone morphogenetic protein 4 isoform X1.	0.890
BMP2	BMP7	A0A341D1S7	A0A341BWL0	Bone morphogenetic protein 2 isoform X1.	Bone morphogenetic protein 7.	0.766
BMP2	BMPR1A	A0A341D1S7	A0A341A962	Bone morphogenetic protein 2 isoform X1.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.999
BMP2	CTNNB1	A0A341D1S7	A0A341C5R9	Bone morphogenetic protein 2 isoform X1.	Catenin beta-1.	0.563
BMP2	FGF10	A0A341D1S7	A0A341B1S0	Bone morphogenetic protein 2 isoform X1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.544
BMP2	FGF2	A0A341D1S7	A0A341BF24	Bone morphogenetic protein 2 isoform X1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.723
BMP2	FGF7	A0A341D1S7	A0A341BPK4	Bone morphogenetic protein 2 isoform X1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.544
BMP2	FGF8	A0A341D1S7	A0A341AJJ9	Bone morphogenetic protein 2 isoform X1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.544