STRINGSTRING
ZNF423 ZNF423 ELL3 ELL3 OTP OTP DLL4 DLL4 APPL2 APPL2 ASCL1 ASCL1 GLI3 GLI3 CIP2A CIP2A SKOR2 SKOR2 NF1 NF1 ID2 ID2 GLI1 GLI1 LIMS2 LIMS2 RHOA RHOA SHH SHH LRRK2 LRRK2 DMRTA2 DMRTA2 CDON CDON LHX5 LHX5 PTN PTN EGF EGF KIFAP3 KIFAP3 TOX TOX TRIM71 TRIM71 FGF2 FGF2 ZNF335 ZNF335 LOC112400428 LOC112400428 FZD9 FZD9 WNT5A WNT5A ADGRG1 ADGRG1 FAM19A1 FAM19A1 CEND1 CEND1 HIF1A HIF1A GPR37L1 GPR37L1 DISP3 DISP3 PTBP2 PTBP2 BTG2 BTG2 PROX1 PROX1 CTNNA1 CTNNA1 PAX6 PAX6 DRD2 DRD2 CTNNB1 CTNNB1 SMARCD3 SMARCD3 FOXG1 FOXG1 NR2E1 NR2E1 DCT DCT FOXO3 FOXO3 VAX1 VAX1 LRP2 LRP2 ILK ILK PTPRZ1 PTPRZ1 RASSF10 RASSF10 LHX1 LHX1 KDM2B KDM2B SMARCA1 SMARCA1 SOX10 SOX10 SMO SMO LHX2 LHX2 RAPGEF1 RAPGEF1 EMX1 EMX1 WNT3A WNT3A FAM19A3 FAM19A3 SLC16A2 SLC16A2 ITGB1 ITGB1 DISC1 DISC1 KDM1A KDM1A FZD3 FZD3 NF2 NF2 CX3CR1 CX3CR1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ZNF423Zinc finger protein 423. (1224 aa)
ELL3RNA polymerase II elongation factor ELL3 isoform X1. (354 aa)
OTPHomeobox protein orthopedia. (325 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
APPL2DCC-interacting protein 13-beta isoform X1. (661 aa)
ASCL1LOW QUALITY PROTEIN: achaete-scute homolog 1. (228 aa)
GLI3Transcriptional activator GLI3. (1587 aa)
CIP2AProtein CIP2A. (908 aa)
SKOR2LOW QUALITY PROTEIN: SKI family transcriptional corepressor 2. (693 aa)
NF1Neurofibromin isoform X1. (2841 aa)
ID2DNA-binding protein inhibitor ID-2. (134 aa)
GLI1Zinc finger protein GLI1 isoform X1. (1106 aa)
LIMS2LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (336 aa)
RHOATransforming protein RhoA. (193 aa)
SHHSonic hedgehog protein. (328 aa)
LRRK2Leucine-rich repeat serine/threonine-protein kinase 2 isoform X1. (2527 aa)
DMRTA2LOW QUALITY PROTEIN: doublesex- and mab-3-related transcription factor A2. (533 aa)
CDONCell adhesion molecule-related/down-regulated by oncogenes. (1279 aa)
LHX5LIM/homeobox protein Lhx5. (326 aa)
PTNPleiotrophin isoform X1. (168 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1238 aa)
KIFAP3Kinesin-associated protein 3. (793 aa)
TOXThymocyte selection-associated high mobility group box protein TOX. (478 aa)
TRIM71E3 ubiquitin-protein ligase TRIM71. (596 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (304 aa)
ZNF335Zinc finger protein 335 isoform X1. (1346 aa)
LOC112400428LOW QUALITY PROTEIN: catenin alpha-1-like. (875 aa)
FZD9Frizzled-9; Belongs to the G-protein coupled receptor Fz/Smo family. (564 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
ADGRG1Adhesion G-protein coupled receptor G1; Belongs to the G-protein coupled receptor 2 family. (685 aa)
FAM19A1Protein FAM19A1. (133 aa)
CEND1Cell cycle exit and neuronal differentiation protein 1. (146 aa)
HIF1AHypoxia-inducible factor 1-alpha. (823 aa)
GPR37L1Prosaposin receptor GPR37L1. (464 aa)
DISP3Protein dispatched homolog 3. (1390 aa)
PTBP2Polypyrimidine tract-binding protein 2 isoform X1. (537 aa)
BTG2Protein BTG2. (162 aa)
PROX1Prospero homeobox protein 1 isoform X1. (737 aa)
CTNNA1Catenin alpha-1. (906 aa)
PAX6Paired box protein Pax-6 isoform X1. (493 aa)
DRD2D(2) dopamine receptor isoform X2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
CTNNB1Catenin beta-1. (781 aa)
SMARCD3annotation not available (495 aa)
FOXG1Forkhead box protein G1. (662 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (385 aa)
DCTL-dopachrome tautomerase isoform X1. (519 aa)
FOXO3Forkhead box protein O3. (672 aa)
VAX1Ventral anterior homeobox 1. (156 aa)
LRP2Low-density lipoprotein receptor-related protein 2 isoform X1. (4651 aa)
ILKIntegrin-linked protein kinase isoform X1. (485 aa)
PTPRZ1Receptor-type tyrosine-protein phosphatase zeta. (2321 aa)
RASSF10Ras association domain-containing protein 10. (501 aa)
LHX1LIM/homeobox protein Lhx1. (406 aa)
KDM2BLysine-specific demethylase 2B. (1309 aa)
SMARCA1Probable global transcription activator SNF2L1 isoform X1. (980 aa)
SOX10Transcription factor SOX-10. (468 aa)
SMOSmoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (783 aa)
LHX2LIM/homeobox protein Lhx2. (406 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1. (1094 aa)
EMX1Homeobox protein EMX1. (288 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
FAM19A3Protein FAM19A3 isoform X1. (146 aa)
SLC16A2Monocarboxylate transporter 8. (438 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
DISC1Disrupted in schizophrenia 1 protein isoform X1. (848 aa)
KDM1ALysine-specific histone demethylase 1A. (730 aa)
FZD3Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (468 aa)
NF2Merlin isoform X3. (619 aa)
CX3CR1CX3C chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (358 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.