51 items (Neophocaena asiaeorientalis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APTX	Aprataxin isoform X1. (355 aa)
	SMAD9	Mothers against decapentaplegic homolog. (440 aa)
	NBN	Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (727 aa)
	SMAD7	Mothers against decapentaplegic homolog. (426 aa)
	SMAD2	Mothers against decapentaplegic homolog. (467 aa)
	SMAD4	Mothers against decapentaplegic homolog. (599 aa)
	STARD9	stAR-related lipid transfer protein 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (4487 aa)
	AGGF1	Angiogenic factor with G patch and FHA domains 1. (714 aa)
	SMAD3	Mothers against decapentaplegic homolog. (376 aa)
	PHF12	PHD finger protein 12 isoform X1. (1022 aa)
	SMAD6	LOW QUALITY PROTEIN: mothers against decapentaplegic homolog 6. (422 aa)
	KIF1C	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (936 aa)
	IRF8	Interferon regulatory factor 8 isoform X1. (427 aa)
	SMAD1	Mothers against decapentaplegic homolog. (465 aa)
	MCRS1	Microspherule protein 1 isoform X1. (462 aa)
	MDC1	Mediator of DNA damage checkpoint protein 1 isoform X1. (2068 aa)
	LOC112395663	Kinesin-like protein KIF28P; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1032 aa)
	TCF19	Transcription factor 19 isoform X1. (344 aa)
	SNIP1	Smad nuclear-interacting protein 1. (394 aa)
	TIFA	TRAF-interacting protein with FHA domain-containing protein A. (185 aa)
	CHFR	E3 ubiquitin-protein ligase CHFR. (634 aa)
	CEP170	Centrosomal protein of 170 kDa isoform X1. (1594 aa)
	APLF	Aprataxin and PNK-like factor isoform X1. (511 aa)
	LOC112398563	Interferon regulatory factor 4-like isoform X1. (406 aa)
	AFDN	Afadin. (1811 aa)
	SLMAP	Sarcolemmal membrane-associated protein isoform X1. (847 aa)
	KIF13B	Kinesin-like protein KIF13B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1969 aa)
	KIF1B	Kinesin-like protein KIF1B isoform X2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1770 aa)
	FHAD1	Forkhead-associated domain-containing protein 1. (1344 aa)
	IRF7	Interferon regulatory factor 7. (474 aa)
	KIF14	Kinesin-like protein KIF14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1639 aa)
	IRF6	Interferon regulatory factor 6 isoform X1. (467 aa)
	TIFAB	TRAF-interacting protein with FHA domain-containing protein B. (247 aa)
	MKI67	Proliferation marker protein Ki-67. (2619 aa)
	SMAD5	Mothers against decapentaplegic homolog. (465 aa)
	PHLDB1	Pleckstrin homology-like domain family B member 1 isoform X1. (1478 aa)
	KIF16B	Kinesin-like protein KIF16B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1316 aa)
	IRF9	LOW QUALITY PROTEIN: interferon regulatory factor 9. (478 aa)
	CEP170B	Centrosomal protein of 170 kDa protein B. (1483 aa)
	KIF1A	Kinesin-like protein KIF1A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1825 aa)
	IRF5	Interferon regulatory factor 5 isoform X1. (517 aa)
	RADIL	Ras-associating and dilute domain-containing protein. (1072 aa)
	KIF13A	Kinesin-like protein KIF13A isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1760 aa)
	SLC4A1AP	Kanadaptin isoform X2. (742 aa)
	IRF4	Interferon regulatory factor 4. (452 aa)
	RNF8	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (487 aa)
	PPP1R8	Nuclear inhibitor of protein phosphatase 1. (378 aa)
	LOC112415334	Ras-interacting protein 1. (615 aa)
	IRF3	Interferon regulatory factor 3. (419 aa)
	PNKP	LOW QUALITY PROTEIN: bifunctional polynucleotide phosphatase/kinase. (500 aa)
	CHEK2	Serine/threonine-protein kinase Chk2. (544 aa)

Your Current Organism:

Neophocaena asiaeorientalis

NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGGF1	RADIL	A0A341AHF6	A0A341CXA3	Angiogenic factor with G patch and FHA domains 1.	Ras-associating and dilute domain-containing protein.	0.596
APLF	APTX	A0A341B6K8	A0A341C3W8	Aprataxin and PNK-like factor isoform X1.	Aprataxin isoform X1.	0.732
APLF	CHFR	A0A341B6K8	A0A341B233	Aprataxin and PNK-like factor isoform X1.	E3 ubiquitin-protein ligase CHFR.	0.685
APLF	MKI67	A0A341B6K8	A0A341C0D3	Aprataxin and PNK-like factor isoform X1.	Proliferation marker protein Ki-67.	0.665
APLF	PNKP	A0A341B6K8	A0A341DCB7	Aprataxin and PNK-like factor isoform X1.	LOW QUALITY PROTEIN: bifunctional polynucleotide phosphatase/kinase.	0.670
APTX	APLF	A0A341C3W8	A0A341B6K8	Aprataxin isoform X1.	Aprataxin and PNK-like factor isoform X1.	0.732
APTX	MDC1	A0A341C3W8	A0A341AUZ2	Aprataxin isoform X1.	Mediator of DNA damage checkpoint protein 1 isoform X1.	0.497
APTX	PNKP	A0A341C3W8	A0A341DCB7	Aprataxin isoform X1.	LOW QUALITY PROTEIN: bifunctional polynucleotide phosphatase/kinase.	0.739
CHEK2	MDC1	A0A341DCJ2	A0A341AUZ2	Serine/threonine-protein kinase Chk2.	Mediator of DNA damage checkpoint protein 1 isoform X1.	0.639
CHEK2	NBN	A0A341DCJ2	A0A341CCH0	Serine/threonine-protein kinase Chk2.	Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.	0.827
CHEK2	RNF8	A0A341DCJ2	A0A341D6H3	Serine/threonine-protein kinase Chk2.	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	0.788
CHFR	APLF	A0A341B233	A0A341B6K8	E3 ubiquitin-protein ligase CHFR.	Aprataxin and PNK-like factor isoform X1.	0.685
CHFR	MDC1	A0A341B233	A0A341AUZ2	E3 ubiquitin-protein ligase CHFR.	Mediator of DNA damage checkpoint protein 1 isoform X1.	0.461
CHFR	MKI67	A0A341B233	A0A341C0D3	E3 ubiquitin-protein ligase CHFR.	Proliferation marker protein Ki-67.	0.621
IRF3	IRF5	A0A341DBK4	A0A341CUK6	Interferon regulatory factor 3.	Interferon regulatory factor 5 isoform X1.	0.538
IRF3	IRF7	A0A341DBK4	A0A341BTM8	Interferon regulatory factor 3.	Interferon regulatory factor 7.	0.991
IRF3	SMAD3	A0A341DBK4	A0A341AJT2	Interferon regulatory factor 3.	Mothers against decapentaplegic homolog.	0.483
IRF4	IRF7	A0A341D586	A0A341BTM8	Interferon regulatory factor 4.	Interferon regulatory factor 7.	0.414
IRF5	IRF3	A0A341CUK6	A0A341DBK4	Interferon regulatory factor 5 isoform X1.	Interferon regulatory factor 3.	0.538
IRF7	IRF3	A0A341BTM8	A0A341DBK4	Interferon regulatory factor 7.	Interferon regulatory factor 3.	0.991