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IL20 IL20 FLT3LG FLT3LG LIF LIF THPO THPO OSM OSM LOC112415378 LOC112415378 LEP LEP LOC112410331 LOC112410331 KITLG KITLG LOC112407025 LOC112407025 IFNB1 IFNB1 IL11 IL11 IL12A IL12A IFNK IFNK IL24 IL24 IL19 IL19 IL10 IL10 CLCF1 CLCF1 CNTF CNTF IL13 IL13 IL4 IL4 IL5 IL5 IL2 IL2 IL21 IL21 CTF1 CTF1 LOC112399259 LOC112399259 EPO EPO IL27 IL27 CSF3 CSF3 CSF1 CSF1 LOC112397463 LOC112397463 PRL PRL CSF2 CSF2 LOC112395028 LOC112395028 LOC112395025 LOC112395025 LOC112395029 LOC112395029 IL6 IL6 LOC112395020 LOC112395020 LOC112395033 LOC112395033 IL26 IL26 IFNE IFNE LOC112395027 LOC112395027 LOC112395023 LOC112395023 IL22 IL22 IL23A IL23A IL15 IL15 IFNG IFNG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IL20LOW QUALITY PROTEIN: interleukin-20. (190 aa)
FLT3LGFms-related tyrosine kinase 3 ligand isoform X1. (297 aa)
LIFLeukemia inhibitory factor. (202 aa)
THPOThrombopoietin isoform X1. (349 aa)
OSMoncostatin-M. (248 aa)
LOC112415378Uncharacterized protein LOC112415378. (178 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
LOC112410331LOW QUALITY PROTEIN: somatotropin-like. (263 aa)
KITLGKit ligand isoform X1. (295 aa)
LOC112407025Interferon alpha-1-like. (189 aa)
IFNB1Interferon beta. (185 aa)
IL11Interleukin-11. (199 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (222 aa)
IFNKInterferon kappa. (207 aa)
IL24Interleukin-24 isoform X1. (183 aa)
IL19Interleukin-19. (177 aa)
IL10Interleukin-10. (178 aa)
CLCF1Cardiotrophin-like cytokine factor 1. (215 aa)
CNTFCiliary neurotrophic factor. (200 aa)
IL13Interleukin-13. (145 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (133 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (135 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (154 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (146 aa)
CTF1LOW QUALITY PROTEIN: cardiotrophin-1. (201 aa)
LOC112399259LOW QUALITY PROTEIN: cardiotrophin-2-like. (202 aa)
EPOErythropoietin. (266 aa)
IL27Interleukin-27 subunit alpha. (238 aa)
CSF3Granulocyte colony-stimulating factor. (195 aa)
CSF1Macrophage colony-stimulating factor 1. (513 aa)
LOC112397463Interleukin-3-like. (149 aa)
PRLProlactin isoform X1. (230 aa)
CSF2Granulocyte-macrophage colony-stimulating factor. (134 aa)
LOC112395028LOW QUALITY PROTEIN: interferon alpha-8-like. (171 aa)
LOC112395025Interferon omega-1-like. (250 aa)
LOC112395029LOW QUALITY PROTEIN: interferon alpha-8-like. (171 aa)
IL6Interleukin-6. (208 aa)
LOC112395020Interferon alpha-1-like. (189 aa)
LOC112395033Interferon omega-1-like. (250 aa)
IL26Interleukin-26. (171 aa)
IFNEInterferon epsilon. (193 aa)
LOC112395027Interferon alpha-1-like. (189 aa)
LOC112395023Interferon alpha-1-like. (189 aa)
IL22Interleukin-22. (189 aa)
IL23AInterleukin-23 subunit alpha. (189 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (180 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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