29 items (Neophocaena asiaeorientalis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC112405151	Cytochrome P450 1B1; Belongs to the cytochrome P450 family. (543 aa)
	AHR	Aryl hydrocarbon receptor. (845 aa)
	LOC112414592	Lanosterol 14-alpha demethylase; Belongs to the cytochrome P450 family. (503 aa)
	LOC112413941	24-hydroxycholesterol 7-alpha-hydroxylase; Belongs to the cytochrome P450 family. (469 aa)
	LOC112413041	Bile acid receptor-like. (492 aa)
	POMC	Pro-opiomelanocortin. (260 aa)
	NCOA1	Nuclear receptor coactivator. (1441 aa)
	ARNT	Aryl hydrocarbon receptor nuclear translocator isoform X1. (790 aa)
	LOC112411895	Sterol 26-hydroxylase, mitochondrial isoform X1; Belongs to the cytochrome P450 family. (571 aa)
	RXRA	Retinoic acid receptor RXR-alpha. (439 aa)
	LOC112410931	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (520 aa)
	FDXR	NADPH:adrenodoxin oxidoreductase, mitochondrial isoform X1. (549 aa)
	FADS6	Fatty acid desaturase 6. (327 aa)
	LOC112409398	Cholesterol 24-hydroxylase; Belongs to the cytochrome P450 family. (501 aa)
	LOC112409665	Cytochrome P450 4V2; Belongs to the cytochrome P450 family. (652 aa)
	LOC112407426	5-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase; Belongs to the cytochrome P450 family. (511 aa)
	FDX1	Adrenodoxin, mitochondrial. (193 aa)
	NR1H4	Bile acid receptor isoform X1. (486 aa)
	CCDC160	Coiled-coil domain-containing protein 160. (325 aa)
	FDX2	Ferredoxin-2, mitochondrial isoform X1. (276 aa)
	LOC112398181	25-hydroxycholesterol 7-alpha-hydroxylase; Belongs to the cytochrome P450 family. (436 aa)
	LOC112397499	Aromatase-like; Belongs to the cytochrome P450 family. (503 aa)
	ARNT2	Aryl hydrocarbon receptor nuclear translocator 2 isoform X1. (747 aa)
	LOC112398221	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (501 aa)
	LOC112397123	Cytochrome P450 11B1, mitochondrial isoform X1; Belongs to the cytochrome P450 family. (503 aa)
	LOC112397422	Aromatase; Belongs to the cytochrome P450 family. (503 aa)
	NCOA2	Nuclear receptor coactivator. (1464 aa)
	LOC112395389	Steroid 21-hydroxylase; Belongs to the cytochrome P450 family. (403 aa)
	AHRR	Aryl hydrocarbon receptor repressor. (693 aa)

Your Current Organism:

Neophocaena asiaeorientalis

NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHR	ARNT	A0A341D7G3	A0A341CXK1	Aryl hydrocarbon receptor.	Aryl hydrocarbon receptor nuclear translocator isoform X1.	0.999
AHR	ARNT2	A0A341D7G3	A0A341B6V4	Aryl hydrocarbon receptor.	Aryl hydrocarbon receptor nuclear translocator 2 isoform X1.	0.995
AHR	NCOA1	A0A341D7G3	A0A341CZR1	Aryl hydrocarbon receptor.	Nuclear receptor coactivator.	0.774
AHR	NCOA2	A0A341D7G3	A0A341AXN1	Aryl hydrocarbon receptor.	Nuclear receptor coactivator.	0.774
AHRR	ARNT	A0A341ADR7	A0A341CXK1	Aryl hydrocarbon receptor repressor.	Aryl hydrocarbon receptor nuclear translocator isoform X1.	0.928
AHRR	ARNT2	A0A341ADR7	A0A341B6V4	Aryl hydrocarbon receptor repressor.	Aryl hydrocarbon receptor nuclear translocator 2 isoform X1.	0.978
AHRR	LOC112405151	A0A341ADR7	A0A341C2Z0	Aryl hydrocarbon receptor repressor.	Cytochrome P450 1B1; Belongs to the cytochrome P450 family.	0.573
AHRR	NCOA1	A0A341ADR7	A0A341CZR1	Aryl hydrocarbon receptor repressor.	Nuclear receptor coactivator.	0.774
AHRR	NCOA2	A0A341ADR7	A0A341AXN1	Aryl hydrocarbon receptor repressor.	Nuclear receptor coactivator.	0.774
ARNT	AHR	A0A341CXK1	A0A341D7G3	Aryl hydrocarbon receptor nuclear translocator isoform X1.	Aryl hydrocarbon receptor.	0.999
ARNT	AHRR	A0A341CXK1	A0A341ADR7	Aryl hydrocarbon receptor nuclear translocator isoform X1.	Aryl hydrocarbon receptor repressor.	0.928
ARNT	ARNT2	A0A341CXK1	A0A341B6V4	Aryl hydrocarbon receptor nuclear translocator isoform X1.	Aryl hydrocarbon receptor nuclear translocator 2 isoform X1.	0.890
ARNT	LOC112405151	A0A341CXK1	A0A341C2Z0	Aryl hydrocarbon receptor nuclear translocator isoform X1.	Cytochrome P450 1B1; Belongs to the cytochrome P450 family.	0.603
ARNT	LOC112413041	A0A341CXK1	A0A341D0V7	Aryl hydrocarbon receptor nuclear translocator isoform X1.	Bile acid receptor-like.	0.419
ARNT	NR1H4	A0A341CXK1	A0A341BWN2	Aryl hydrocarbon receptor nuclear translocator isoform X1.	Bile acid receptor isoform X1.	0.419
ARNT	RXRA	A0A341CXK1	A0A341CV07	Aryl hydrocarbon receptor nuclear translocator isoform X1.	Retinoic acid receptor RXR-alpha.	0.442
ARNT2	AHR	A0A341B6V4	A0A341D7G3	Aryl hydrocarbon receptor nuclear translocator 2 isoform X1.	Aryl hydrocarbon receptor.	0.995
ARNT2	AHRR	A0A341B6V4	A0A341ADR7	Aryl hydrocarbon receptor nuclear translocator 2 isoform X1.	Aryl hydrocarbon receptor repressor.	0.978
ARNT2	ARNT	A0A341B6V4	A0A341CXK1	Aryl hydrocarbon receptor nuclear translocator 2 isoform X1.	Aryl hydrocarbon receptor nuclear translocator isoform X1.	0.890
ARNT2	LOC112413041	A0A341B6V4	A0A341D0V7	Aryl hydrocarbon receptor nuclear translocator 2 isoform X1.	Bile acid receptor-like.	0.419