STRINGSTRING
SMAD3 SMAD3 STRAP STRAP SMURF2 SMURF2 UBA52 UBA52 PPP1R15A PPP1R15A TGFB1 TGFB1 LDLRAD4 LDLRAD4 STUB1 STUB1 MTMR4 MTMR4 SMAD2 SMAD2 SMAD7 SMAD7 RPS27A RPS27A PMEPA1 PMEPA1 BAMBI BAMBI TGFBR2 TGFBR2 LOC112394096 LOC112394096 TGFBR1 TGFBR1 LOC112392958 LOC112392958
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMAD3Mothers against decapentaplegic homolog. (376 aa)
STRAPSerine-threonine kinase receptor-associated protein isoform X1. (350 aa)
SMURF2E3 ubiquitin-protein ligase. (738 aa)
UBA52ubiquitin-60S ribosomal protein L40. (128 aa)
PPP1R15ALOW QUALITY PROTEIN: protein phosphatase 1 regulatory subunit 15A. (568 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
LDLRAD4LOW QUALITY PROTEIN: low-density lipoprotein receptor class A domain-containing protein 4. (322 aa)
STUB1E3 ubiquitin-protein ligase CHIP. (303 aa)
MTMR4Myotubularin-related protein 4 isoform X1. (1211 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
PMEPA1Protein TMEPAI isoform X1. (269 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog. (218 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa)
LOC112394096Ubiquitin-like. (144 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (438 aa)
LOC112392958ubiquitin-40S ribosomal protein S27a-like. (157 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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