STRINGSTRING
TGFB1 TGFB1 LTBP4 LTBP4 PPP1R15A PPP1R15A KXD1 KXD1 UBA52 UBA52 FURIN FURIN ITGB1 ITGB1 LDLRAD4 LDLRAD4 ITGB3 ITGB3 SMURF2 SMURF2 STUB1 STUB1 MTMR4 MTMR4 SMAD4 SMAD4 SMAD2 SMAD2 ITGB5 ITGB5 SMAD7 SMAD7 NEDD8 NEDD8 UBB UBB RPS27A RPS27A CBL CBL ITGAV ITGAV PMEPA1 PMEPA1 BAMBI BAMBI ITGA8 ITGA8 LTBP3 LTBP3 TGFBR2 TGFBR2 UBE2M UBE2M FBN1 FBN1 ZFYVE9 ZFYVE9 PCSK4 PCSK4 ITGB8 ITGB8 TGFB2 TGFB2 LTBP2 LTBP2 TGFB3 TGFB3 ITGB6 ITGB6 LOC112394096 LOC112394096 TGFBR1 TGFBR1 SMAD3 SMAD3 LOC112392958 LOC112392958 STRAP STRAP LTBP1 LTBP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
LTBP4Latent-transforming growth factor beta-binding protein 4 isoform X1. (1433 aa)
PPP1R15ALOW QUALITY PROTEIN: protein phosphatase 1 regulatory subunit 15A. (568 aa)
KXD1kxDL motif-containing protein 1. (176 aa)
UBA52ubiquitin-60S ribosomal protein L40. (128 aa)
FURINFurin; Belongs to the peptidase S8 family. (792 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
LDLRAD4LOW QUALITY PROTEIN: low-density lipoprotein receptor class A domain-containing protein 4. (322 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (789 aa)
SMURF2E3 ubiquitin-protein ligase. (738 aa)
STUB1E3 ubiquitin-protein ligase CHIP. (303 aa)
MTMR4Myotubularin-related protein 4 isoform X1. (1211 aa)
SMAD4Mothers against decapentaplegic homolog. (599 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (692 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
NEDD8NEDD8 isoform X1. (98 aa)
UBBpolyubiquitin-B. (153 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
CBLE3 ubiquitin-protein ligase CBL. (915 aa)
ITGAVIntegrin alpha-V; Belongs to the integrin alpha chain family. (985 aa)
PMEPA1Protein TMEPAI isoform X1. (269 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog. (218 aa)
ITGA8Integrin alpha-8; Belongs to the integrin alpha chain family. (1250 aa)
LTBP3Latent-transforming growth factor beta-binding protein 3 isoform X1. (1211 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa)
UBE2MNEDD8-conjugating enzyme Ubc12; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
FBN1Fibrillin-1. (2871 aa)
ZFYVE9Zinc finger FYVE domain-containing protein. (1422 aa)
PCSK4Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (765 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (767 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
LTBP2Latent-transforming growth factor beta-binding protein 2. (1772 aa)
TGFB3Transforming growth factor beta-3. (456 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (808 aa)
LOC112394096Ubiquitin-like. (144 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (438 aa)
SMAD3Mothers against decapentaplegic homolog. (376 aa)
LOC112392958ubiquitin-40S ribosomal protein S27a-like. (157 aa)
STRAPSerine-threonine kinase receptor-associated protein isoform X1. (350 aa)
LTBP1Latent-transforming growth factor beta-binding protein 1 isoform X1. (1519 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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