node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCND1 | CCND2 | A0A341BS75 | A0A341AH14 | G1/S-specific cyclin-D1; Belongs to the cyclin family. | G1/S-specific cyclin-D2; Belongs to the cyclin family. | 0.905 |
CCND1 | CCND3 | A0A341BS75 | A0A341D5L7 | G1/S-specific cyclin-D1; Belongs to the cyclin family. | G1/S-specific cyclin-D3 isoform X3; Belongs to the cyclin family. | 0.914 |
CCND1 | CDK6 | A0A341BS75 | A0A341D7E0 | G1/S-specific cyclin-D1; Belongs to the cyclin family. | Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. | 0.999 |
CCND1 | RUNX1 | A0A341BS75 | A0A341CHX4 | G1/S-specific cyclin-D1; Belongs to the cyclin family. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.646 |
CCND2 | CCND1 | A0A341AH14 | A0A341BS75 | G1/S-specific cyclin-D2; Belongs to the cyclin family. | G1/S-specific cyclin-D1; Belongs to the cyclin family. | 0.905 |
CCND2 | CCND3 | A0A341AH14 | A0A341D5L7 | G1/S-specific cyclin-D2; Belongs to the cyclin family. | G1/S-specific cyclin-D3 isoform X3; Belongs to the cyclin family. | 0.891 |
CCND2 | CDK6 | A0A341AH14 | A0A341D7E0 | G1/S-specific cyclin-D2; Belongs to the cyclin family. | Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. | 0.999 |
CCND2 | RUNX1 | A0A341AH14 | A0A341CHX4 | G1/S-specific cyclin-D2; Belongs to the cyclin family. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.588 |
CCND3 | CCND1 | A0A341D5L7 | A0A341BS75 | G1/S-specific cyclin-D3 isoform X3; Belongs to the cyclin family. | G1/S-specific cyclin-D1; Belongs to the cyclin family. | 0.914 |
CCND3 | CCND2 | A0A341D5L7 | A0A341AH14 | G1/S-specific cyclin-D3 isoform X3; Belongs to the cyclin family. | G1/S-specific cyclin-D2; Belongs to the cyclin family. | 0.891 |
CCND3 | CDK6 | A0A341D5L7 | A0A341D7E0 | G1/S-specific cyclin-D3 isoform X3; Belongs to the cyclin family. | Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. | 0.999 |
CCND3 | RUNX1 | A0A341D5L7 | A0A341CHX4 | G1/S-specific cyclin-D3 isoform X3; Belongs to the cyclin family. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.588 |
CDK6 | CCND1 | A0A341D7E0 | A0A341BS75 | Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. | G1/S-specific cyclin-D1; Belongs to the cyclin family. | 0.999 |
CDK6 | CCND2 | A0A341D7E0 | A0A341AH14 | Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. | G1/S-specific cyclin-D2; Belongs to the cyclin family. | 0.999 |
CDK6 | CCND3 | A0A341D7E0 | A0A341D5L7 | Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. | G1/S-specific cyclin-D3 isoform X3; Belongs to the cyclin family. | 0.999 |
CDK6 | RUNX1 | A0A341D7E0 | A0A341CHX4 | Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.752 |
LOC112409948 | PTPN11 | A0A341CN75 | A0A341B368 | Tyrosine-protein phosphatase non-receptor type 11-like isoform X1. | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.843 |
LOC112409948 | RUNX1 | A0A341CN75 | A0A341CHX4 | Tyrosine-protein phosphatase non-receptor type 11-like isoform X1. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.594 |
PML | RUNX1 | A0A341CS01 | A0A341CHX4 | Protein PML isoform X1. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.960 |
PTPN11 | LOC112409948 | A0A341B368 | A0A341CN75 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | Tyrosine-protein phosphatase non-receptor type 11-like isoform X1. | 0.843 |