12 items (Neophocaena asiaeorientalis) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RUNX2	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (408 aa)
	HES4	Transcription factor HES-4. (184 aa)
	SP7	Transcription factor Sp7. (431 aa)
	SMAD1	Mothers against decapentaplegic homolog. (465 aa)
	SP8	Transcription factor Sp8. (320 aa)
	ZNF423	Zinc finger protein 423. (1224 aa)
	RBM14	RNA-binding protein 14 isoform X1. (669 aa)
	AR	Androgen receptor isoform X1. (893 aa)
	HES1	Transcription factor HES-1. (280 aa)
	SMAD4	Mothers against decapentaplegic homolog. (599 aa)
	UCMA	Unique cartilage matrix-associated protein. (138 aa)
	ZNF521	Zinc finger protein 521 isoform X1. (1534 aa)

Your Current Organism:

Neophocaena asiaeorientalis

NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AR	RUNX2	A0A341BZY8	A0A341D3Q3	Androgen receptor isoform X1.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.972
AR	SMAD4	A0A341BZY8	A0A341CF47	Androgen receptor isoform X1.	Mothers against decapentaplegic homolog.	0.538
HES1	HES4	A0A341C1R9	A0A341CMM0	Transcription factor HES-1.	Transcription factor HES-4.	0.760
HES4	HES1	A0A341CMM0	A0A341C1R9	Transcription factor HES-4.	Transcription factor HES-1.	0.760
RBM14	RUNX2	A0A341BRR7	A0A341D3Q3	RNA-binding protein 14 isoform X1.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.955
RUNX2	AR	A0A341D3Q3	A0A341BZY8	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	Androgen receptor isoform X1.	0.972
RUNX2	RBM14	A0A341D3Q3	A0A341BRR7	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	RNA-binding protein 14 isoform X1.	0.955
RUNX2	SMAD1	A0A341D3Q3	A0A341ARX3	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	Mothers against decapentaplegic homolog.	0.745
RUNX2	SMAD4	A0A341D3Q3	A0A341CF47	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	Mothers against decapentaplegic homolog.	0.830
RUNX2	SP7	A0A341D3Q3	A0A341AQP5	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	Transcription factor Sp7.	0.745
SMAD1	RUNX2	A0A341ARX3	A0A341D3Q3	Mothers against decapentaplegic homolog.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.745
SMAD1	SMAD4	A0A341ARX3	A0A341CF47	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.998
SMAD4	AR	A0A341CF47	A0A341BZY8	Mothers against decapentaplegic homolog.	Androgen receptor isoform X1.	0.538
SMAD4	RUNX2	A0A341CF47	A0A341D3Q3	Mothers against decapentaplegic homolog.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.830
SMAD4	SMAD1	A0A341CF47	A0A341ARX3	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.998
SMAD4	ZNF423	A0A341CF47	A0A341BK49	Mothers against decapentaplegic homolog.	Zinc finger protein 423.	0.450
SP7	RUNX2	A0A341AQP5	A0A341D3Q3	Transcription factor Sp7.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.745
ZNF423	SMAD4	A0A341BK49	A0A341CF47	Zinc finger protein 423.	Mothers against decapentaplegic homolog.	0.450