STRINGSTRING
RUNX2 RUNX2 HES4 HES4 SP7 SP7 SMAD1 SMAD1 SP8 SP8 ZNF423 ZNF423 RBM14 RBM14 AR AR HES1 HES1 SMAD4 SMAD4 UCMA UCMA ZNF521 ZNF521
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RUNX2Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (408 aa)
HES4Transcription factor HES-4. (184 aa)
SP7Transcription factor Sp7. (431 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
SP8Transcription factor Sp8. (320 aa)
ZNF423Zinc finger protein 423. (1224 aa)
RBM14RNA-binding protein 14 isoform X1. (669 aa)
ARAndrogen receptor isoform X1. (893 aa)
HES1Transcription factor HES-1. (280 aa)
SMAD4Mothers against decapentaplegic homolog. (599 aa)
UCMAUnique cartilage matrix-associated protein. (138 aa)
ZNF521Zinc finger protein 521 isoform X1. (1534 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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