STRINGSTRING
SMAD5 SMAD5 SMAD2 SMAD2 SMAD4 SMAD4 F11R F11R NOG NOG MTMR4 MTMR4 NCOR2 NCOR2 TGIF1 TGIF1 STUB1 STUB1 INHBB INHBB CCNK CCNK LOC112410685 LOC112410685 CCNC CCNC LOC112409615 LOC112409615 LOC112409616 LOC112409616 PRKCZ PRKCZ SKI SKI CER1 CER1 SMURF2 SMURF2 ITGB3 ITGB3 MKX MKX ITGB5 ITGB5 SMAD7 SMAD7 ACVR2B ACVR2B CCNQ CCNQ ZFYVE16 ZFYVE16 CDK8 CDK8 SMAD9 SMAD9 NEDD4L NEDD4L NEDD8 NEDD8 NCOR1 NCOR1 UBB UBB RPS27A RPS27A TFDP1 TFDP1 CBL CBL ITGAV ITGAV LOC112403425 LOC112403425 PMEPA1 PMEPA1 BAMBI BAMBI ITGA8 ITGA8 CHRDL2 CHRDL2 DRAP1 DRAP1 MEN1 MEN1 CHRDL1 CHRDL1 LTBP3 LTBP3 IRX6 IRX6 IRX5 IRX5 IRX3 IRX3 ZCCHC4 ZCCHC4 SMURF1 SMURF1 MAPK3 MAPK3 ACVR2A ACVR2A TGFBR2 TGFBR2 TGIF2 TGIF2 RBL1 RBL1 HDAC1 HDAC1 FOXH1 FOXH1 UBE2M UBE2M CDK19 CDK19 LOC112396051 LOC112396051 FST FST FBN1 FBN1 PARP1 PARP1 ZFYVE9 ZFYVE9 PCSK4 PCSK4 AMH AMH LOC112395747 LOC112395747 ITGB8 ITGB8 TGFB2 TGFB2 GDF2 GDF2 LTBP2 LTBP2 PARD3B PARD3B TGFB3 TGFB3 BMP10 BMP10 ATP1B4 ATP1B4 BMPR2 BMPR2 RHOA RHOA CCNT1 CCNT1 AMHR2 AMHR2 SNW1 SNW1 SMAD1 SMAD1 SP1 SP1 ACVRL1 ACVRL1 ACVR1 ACVR1 ITGB6 ITGB6 ACVR1C ACVR1C LOC112394096 LOC112394096 ACVR1B ACVR1B SMAD6 SMAD6 BMPR1B BMPR1B SKIL SKIL TGFBR1 TGFBR1 LOC112393165 LOC112393165 SMAD3 SMAD3 LOC112392958 LOC112392958 PARD6A PARD6A INHBA INHBA E2F4 E2F4 STRAP STRAP LTBP1 LTBP1 IRX1 IRX1 E2F5 E2F5 PPM1A PPM1A IRX2 IRX2 IRX4 IRX4 BMPR1A BMPR1A CDK9 CDK9 CGN CGN MAPK1 MAPK1 LDLRAD4 LDLRAD4 CCNT2 CCNT2 TRIM33 TRIM33 BMP2 BMP2 PARD3 PARD3 ITGB1 ITGB1 FURIN FURIN UBA52 UBA52 KXD1 KXD1 DAND5 DAND5 JUNB JUNB PPP1R15A PPP1R15A TGFB1 TGFB1 WWTR1 WWTR1 TFDP2 TFDP2 FSTL1 FSTL1 LTBP4 LTBP4 MEIS3 MEIS3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMAD5Mothers against decapentaplegic homolog. (465 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
SMAD4Mothers against decapentaplegic homolog. (599 aa)
F11RJunctional adhesion molecule A isoform X1. (299 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
MTMR4Myotubularin-related protein 4 isoform X1. (1211 aa)
NCOR2LOW QUALITY PROTEIN: nuclear receptor corepressor 2. (2409 aa)
TGIF1Homeobox protein TGIF1 isoform X1. (272 aa)
STUB1E3 ubiquitin-protein ligase CHIP. (303 aa)
INHBBInhibin beta B chain. (345 aa)
CCNKcyclin-K; Belongs to the cyclin family. (452 aa)
LOC112410685E3 ubiquitin-protein ligase Arkadia isoform X1. (796 aa)
CCNCcyclin-C isoform X1; Belongs to the cyclin family. (283 aa)
LOC112409615Probable ubiquitin carboxyl-terminal hydrolase FAF-X. (235 aa)
LOC112409616Probable ubiquitin carboxyl-terminal hydrolase FAF-X; Belongs to the peptidase C19 family. (2060 aa)
PRKCZLOW QUALITY PROTEIN: protein kinase C zeta type; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (546 aa)
SKISki oncogene. (669 aa)
CER1Cerberus isoform X1. (273 aa)
SMURF2E3 ubiquitin-protein ligase. (738 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (789 aa)
MKXHomeobox protein Mohawk. (347 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (692 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (508 aa)
CCNQcyclin-Q isoform X1. (233 aa)
ZFYVE16Zinc finger FYVE domain-containing protein 16 isoform X1. (1554 aa)
CDK8Cyclin-dependent kinase 8 isoform X1. (404 aa)
SMAD9Mothers against decapentaplegic homolog. (440 aa)
NEDD4LE3 ubiquitin-protein ligase NEDD4-like isoform X1. (1247 aa)
NEDD8NEDD8 isoform X1. (98 aa)
NCOR1Nuclear receptor corepressor 1 isoform X1. (2454 aa)
UBBpolyubiquitin-B. (153 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
TFDP1Transcription factor. (410 aa)
CBLE3 ubiquitin-protein ligase CBL. (915 aa)
ITGAVIntegrin alpha-V; Belongs to the integrin alpha chain family. (985 aa)
LOC112403425Protein kinase C zeta type-like. (85 aa)
PMEPA1Protein TMEPAI isoform X1. (269 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog. (218 aa)
ITGA8Integrin alpha-8; Belongs to the integrin alpha chain family. (1250 aa)
CHRDL2Chordin-like protein 2 isoform X1. (452 aa)
DRAP1Dr1-associated corepressor. (205 aa)
MEN1Menin isoform X1. (616 aa)
CHRDL1Chordin-like protein 1. (458 aa)
LTBP3Latent-transforming growth factor beta-binding protein 3 isoform X1. (1211 aa)
IRX6Iroquois-class homeodomain protein IRX-6. (443 aa)
IRX5Iroquois-class homeodomain protein IRX-5. (483 aa)
IRX3Iroquois-class homeodomain protein IRX-3. (501 aa)
ZCCHC4Zinc finger CCHC domain-containing protein 4. (513 aa)
SMURF1E3 ubiquitin-protein ligase SMURF1. (718 aa)
MAPK3Mitogen-activated protein kinase 3. (265 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa)
TGIF2Homeobox protein TGIF2. (237 aa)
RBL1Retinoblastoma-like protein 1 isoform X1. (1073 aa)
HDAC1Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (419 aa)
FOXH1Forkhead box protein H1. (360 aa)
UBE2MNEDD8-conjugating enzyme Ubc12; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
CDK19Cyclin-dependent kinase 19 isoform X1. (502 aa)
LOC112396051Probable ubiquitin carboxyl-terminal hydrolase FAF-X isoform X1; Belongs to the peptidase C19 family. (2556 aa)
FSTFollistatin. (344 aa)
FBN1Fibrillin-1. (2871 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1013 aa)
ZFYVE9Zinc finger FYVE domain-containing protein. (1422 aa)
PCSK4Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (765 aa)
AMHMuellerian-inhibiting factor. (383 aa)
LOC112395747LOW QUALITY PROTEIN: ubiquitin-conjugating enzyme E2 D1-like; Belongs to the ubiquitin-conjugating enzyme family. (190 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (767 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
GDF2Growth/differentiation factor 2. (431 aa)
LTBP2Latent-transforming growth factor beta-binding protein 2. (1772 aa)
PARD3BPartitioning defective 3 homolog B. (1202 aa)
TGFB3Transforming growth factor beta-3. (456 aa)
BMP10Bone morphogenetic protein 10. (423 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (356 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1012 aa)
RHOATransforming protein RhoA. (193 aa)
CCNT1cyclin-T1 isoform X1; Belongs to the cyclin family. (727 aa)
AMHR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (584 aa)
SNW1SNW domain-containing protein 1. (536 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
SP1Transcription factor Sp1. (780 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (515 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (808 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
LOC112394096Ubiquitin-like. (144 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (453 aa)
SMAD6LOW QUALITY PROTEIN: mothers against decapentaplegic homolog 6. (422 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
SKILLOW QUALITY PROTEIN: ski-like protein. (664 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (438 aa)
LOC112393165E3 ubiquitin-protein ligase Arkadia-like isoform X1. (216 aa)
SMAD3Mothers against decapentaplegic homolog. (376 aa)
LOC112392958ubiquitin-40S ribosomal protein S27a-like. (157 aa)
PARD6APartitioning defective 6 homolog alpha isoform X1. (346 aa)
INHBAInhibin beta A chain. (474 aa)
E2F4Transcription factor E2F4 isoform X1. (405 aa)
STRAPSerine-threonine kinase receptor-associated protein isoform X1. (350 aa)
LTBP1Latent-transforming growth factor beta-binding protein 1 isoform X1. (1519 aa)
IRX1Iroquois-class homeodomain protein IRX-1. (303 aa)
E2F5Transcription factor E2F5. (391 aa)
PPM1AProtein phosphatase 1A. (382 aa)
IRX2Iroquois-class homeodomain protein IRX-2. (256 aa)
IRX4Iroquois-class homeodomain protein IRX-4. (524 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
CDK9Cyclin-dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa)
CGNCingulin isoform X1. (1194 aa)
MAPK1Mitogen-activated protein kinase. (343 aa)
LDLRAD4LOW QUALITY PROTEIN: low-density lipoprotein receptor class A domain-containing protein 4. (322 aa)
CCNT2cyclin-T2 isoform X1; Belongs to the cyclin family. (742 aa)
TRIM33E3 ubiquitin-protein ligase TRIM33 isoform X1. (1127 aa)
BMP2Bone morphogenetic protein 2 isoform X1. (395 aa)
PARD3LOW QUALITY PROTEIN: partitioning defective 3 homolog. (1251 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
FURINFurin; Belongs to the peptidase S8 family. (792 aa)
UBA52ubiquitin-60S ribosomal protein L40. (128 aa)
KXD1kxDL motif-containing protein 1. (176 aa)
DAND5LOW QUALITY PROTEIN: DAN domain family member 5. (185 aa)
JUNBTranscription factor jun-B. (347 aa)
PPP1R15ALOW QUALITY PROTEIN: protein phosphatase 1 regulatory subunit 15A. (568 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
WWTR1WW domain-containing transcription regulator protein 1. (400 aa)
TFDP2Transcription factor Dp-2 isoform X1. (470 aa)
FSTL1Follistatin-related protein 1. (307 aa)
LTBP4Latent-transforming growth factor beta-binding protein 4 isoform X1. (1433 aa)
MEIS3Homeobox protein Meis3 isoform X8. (412 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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