STRINGSTRING
METTL25 METTL25 LAMTOR3 LAMTOR3 ATP6V0D1 ATP6V0D1 DMRT2 DMRT2 ATP6V1A ATP6V1A DMRT3 DMRT3 ITFG2 ITFG2 CEBPG CEBPG ATP6V1E1 ATP6V1E1 LAMTOR1 LAMTOR1 EIF2AK4 EIF2AK4 ATP6V0D2 ATP6V0D2 SESN3 SESN3 SZT2 SZT2 LOC112400774 LOC112400774 NPRL2 NPRL2 FNIP2 FNIP2 RRAGA RRAGA CASTOR2 CASTOR2 ATP6V1D ATP6V1D RRAGD RRAGD LAMTOR2 LAMTOR2 TCIRG1 TCIRG1 LOC112402169 LOC112402169 MTOR MTOR ATF3 ATF3 SH3BP4 SH3BP4 FLCN FLCN ATP6V0E1 ATP6V0E1 ATP6V1E2 ATP6V1E2 LOC112405295 LOC112405295 RHEB RHEB ATP6V0E2 ATP6V0E2 CRYGN CRYGN SESN1 SESN1 ATP6V1B1 ATP6V1B1 ATP6V1C1 ATP6V1C1 PPP1R3A PPP1R3A IMPACT IMPACT BMT2 BMT2 WDR24 WDR24 ATP6V0C ATP6V0C NPRL3 NPRL3 MLST8 MLST8 ATP6V0B ATP6V0B RPTOR RPTOR ATP6V1B2 ATP6V1B2 ATP6V1F ATP6V1F ATP6V1G1 ATP6V1G1 SEH1L SEH1L ATP6V1G3 ATP6V1G3 CNST CNST SLC38A9 SLC38A9 MIOS MIOS SESN2 SESN2 DMRTA1 DMRTA1 CASTOR1 CASTOR1 DEPDC5 DEPDC5 LIM2 LIM2 KPTN KPTN DMRTC2 DMRTC2 LAMTOR4 LAMTOR4 TXNDC11 TXNDC11 CRYBB3 CRYBB3 GCN1 GCN1 ATP6V1H ATP6V1H FNIP1 FNIP1 LAMTOR5 LAMTOR5 KIAA1671 KIAA1671 SEC13 SEC13 DMRTA2 DMRTA2 DMRTB1 DMRTB1 LOC112396523 LOC112396523 ATP6V1G2 ATP6V1G2 ATP6V1C2 ATP6V1C2 ATF4 ATF4 RRAGC RRAGC MACC1 MACC1 DDIT3 DDIT3 CUNH12orf66 CUNH12orf66 WDR59 WDR59 RHEBL1 RHEBL1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
METTL25Methyltransferase-like protein 25. (602 aa)
LAMTOR3Ragulator complex protein LAMTOR3 isoform X1. (125 aa)
ATP6V0D1V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa)
DMRT2Doublesex- and mab-3-related transcription factor 2. (561 aa)
ATP6V1AV-type proton ATPase catalytic subunit A. (618 aa)
DMRT3Doublesex- and mab-3-related transcription factor 3. (473 aa)
ITFG2KICSTOR complex protein ITFG2. (444 aa)
CEBPGCCAAT/enhancer-binding protein gamma. (185 aa)
ATP6V1E1V-type proton ATPase subunit E 1. (226 aa)
LAMTOR1Ragulator complex protein LAMTOR1. (161 aa)
EIF2AK4eIF-2-alpha kinase GCN2 isoform X1. (1670 aa)
ATP6V0D2V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (350 aa)
SESN3Sestrin-3. (414 aa)
SZT2KICSTOR complex protein SZT2 isoform X1. (3434 aa)
LOC112400774Ragulator complex protein LAMTOR2-like isoform X1. (125 aa)
NPRL2GATOR complex protein NPRL2 isoform X1. (380 aa)
FNIP2Folliculin-interacting protein 2. (950 aa)
RRAGARas-related GTP-binding protein A. (313 aa)
CASTOR2Cytosolic arginine sensor for mTORC1 subunit 2. (361 aa)
ATP6V1DV-type proton ATPase subunit D. (247 aa)
RRAGDRas-related GTP-binding protein D. (396 aa)
LAMTOR2Ragulator complex protein LAMTOR2. (125 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (589 aa)
LOC112402169V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (259 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2548 aa)
ATF3Cyclic AMP-dependent transcription factor ATF-3. (181 aa)
SH3BP4SH3 domain-binding protein 4. (959 aa)
FLCNFolliculin isoform X1. (576 aa)
ATP6V0E1V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (81 aa)
ATP6V1E2LOW QUALITY PROTEIN: V-type proton ATPase subunit E 2. (211 aa)
LOC112405295Doublesex- and mab-3-related transcription factor C2-like. (215 aa)
RHEBGTP-binding protein Rheb. (263 aa)
ATP6V0E2V-type proton ATPase subunit e 2. (112 aa)
CRYGNGamma-crystallin N isoform X1; Belongs to the beta/gamma-crystallin family. (183 aa)
SESN1Sestrin-1 isoform X1. (551 aa)
ATP6V1B1Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (513 aa)
ATP6V1C1V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (382 aa)
PPP1R3AProtein phosphatase 1 regulatory subunit 3A. (1116 aa)
IMPACTProtein IMPACT isoform X1. (318 aa)
BMT2S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...] (405 aa)
WDR24GATOR complex protein WDR24. (809 aa)
ATP6V0CV-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa)
NPRL3GATOR complex protein NPRL3 isoform X1. (621 aa)
MLST8Target of rapamycin complex subunit LST8 isoform X1. (326 aa)
ATP6V0BV-type proton ATPase 21 kDa proteolipid subunit isoform X1; Belongs to the V-ATPase proteolipid subunit family. (233 aa)
RPTORRegulatory-associated protein of mTOR isoform X1. (1336 aa)
ATP6V1B2Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (511 aa)
ATP6V1FV-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (119 aa)
ATP6V1G1V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
SEH1LNucleoporin SEH1 isoform X2; Belongs to the WD repeat SEC13 family. (423 aa)
ATP6V1G3V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
CNSTConsortin isoform X1. (722 aa)
SLC38A9Sodium-coupled neutral amino acid transporter 9 isoform X1. (561 aa)
MIOSGATOR complex protein MIOS isoform X1. (875 aa)
SESN2Sestrin-2. (471 aa)
DMRTA1Doublesex- and mab-3-related transcription factor A1. (498 aa)
CASTOR1Cytosolic arginine sensor for mTORC1 subunit 1 isoform X1. (329 aa)
DEPDC5GATOR complex protein DEPDC5 isoform X1. (1650 aa)
LIM2Lens fiber membrane intrinsic protein; Present in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it may contribute to cell junctional organization. Acts as a receptor for calmodulin. May play an important role in both lens development and cataractogenesis; Belongs to the PMP-22/EMP/MP20 family. (218 aa)
KPTNKICSTOR complex protein kaptin. (435 aa)
DMRTC2Doublesex- and mab-3-related transcription factor C2. (349 aa)
LAMTOR4Ragulator complex protein LAMTOR4 isoform X1. (172 aa)
TXNDC11Thioredoxin domain-containing protein 11 isoform X1. (954 aa)
CRYBB3Beta-crystallin B3; Belongs to the beta/gamma-crystallin family. (211 aa)
GCN1eIF-2-alpha kinase activator GCN1. (2671 aa)
ATP6V1HV-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (480 aa)
FNIP1Folliculin-interacting protein 1 isoform X1. (1165 aa)
LAMTOR5Ragulator complex protein LAMTOR5. (91 aa)
KIAA1671Uncharacterized protein KIAA1671 homolog. (1812 aa)
SEC13Protein SEC13 homolog; Belongs to the WD repeat SEC13 family. (305 aa)
DMRTA2LOW QUALITY PROTEIN: doublesex- and mab-3-related transcription factor A2. (533 aa)
DMRTB1LOW QUALITY PROTEIN: doublesex- and mab-3-related transcription factor B1. (379 aa)
LOC112396523Ras-related GTP-binding protein B isoform X1. (374 aa)
ATP6V1G2V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
ATP6V1C2V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (427 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4. (350 aa)
RRAGCRas-related GTP-binding protein C. (412 aa)
MACC1LOW QUALITY PROTEIN: metastasis-associated in colon cancer protein 1. (850 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa)
CUNH12orf66KICSTOR complex protein C12orf66 homolog. (445 aa)
WDR59GATOR complex protein WDR59 isoform X1. (974 aa)
RHEBL1GTPase RhebL1 isoform X1. (183 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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