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PRTFDC1 PRTFDC1 GDAP1 GDAP1 SPSB4 SPSB4 LOC112402342 LOC112402342 LOC112403217 LOC112403217 CDA CDA UCKL1 UCKL1 DPYD DPYD NME6 NME6 FBXO45 FBXO45 NME2 NME2 LOC112403992 LOC112403992 CES5A CES5A LOC112404710 LOC112404710 NME5 NME5 GSTA4 GSTA4 LOC112406855 LOC112406855 UMPS UMPS DPYS DPYS RRM2B RRM2B TPMT TPMT MPO MPO LOC112408243 LOC112408243 LOC112408499 LOC112408499 NME4 NME4 SPSB3 SPSB3 MRPS34 MRPS34 NME3 NME3 PUSL1 PUSL1 TK1 TK1 FAM78A FAM78A LOC112411044 LOC112411044 LOC112411197 LOC112411197 UCK1 UCK1 IMPDH1 IMPDH1 FAM78B FAM78B UCK2 UCK2 LOC112412163 LOC112412163 FBXO41 FBXO41 LOC112412315 LOC112412315 LOC112412247 LOC112412247 UPP1 UPP1 UPB1 UPB1 CES1 CES1 LOC112402344 LOC112402344 RRM1 RRM1 XDH XDH SPSB2 SPSB2 TK2 TK2 CES2 CES2 MGST1 MGST1 LOC112393216 LOC112393216 UPP2 UPP2 LOC112392999 LOC112392999 GSTO1 GSTO1 MGST2 MGST2 PFDN5 PFDN5 LOC112395053 LOC112395053 IMPDH2 IMPDH2 RRM2 RRM2 DALRD3 DALRD3 CMPK1 CMPK1 DUT DUT PUS3 PUS3 PUS1 PUS1 SLC12A1 SLC12A1 LOC112397404 LOC112397404 LOC112397401 LOC112397401 GMPS GMPS NME7 NME7 LOC112397411 LOC112397411 LOC112397818 LOC112397818 MGST3 MGST3 FBXL20 FBXL20 FBXL2 FBXL2 ITPA ITPA LOC112399556 LOC112399556 GUSB GUSB HPRT1 HPRT1 GDAP1L1 GDAP1L1 SPSB1 SPSB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRTFDC1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (208 aa)
GDAP1Ganglioside-induced differentiation-associated protein 1; Belongs to the GST superfamily. (358 aa)
SPSB4SPRY domain-containing SOCS box protein 4. (273 aa)
LOC112402342Glutathione S-transferase P-like isoform X1. (254 aa)
LOC112403217Liver carboxylesterase 1-like. (412 aa)
CDACytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (146 aa)
UCKL1Uridine-cytidine kinase; Belongs to the uridine kinase family. (537 aa)
DPYDDihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. (1025 aa)
NME6Nucleoside diphosphate kinase. (202 aa)
FBXO45F-box/SPRY domain-containing protein 1. (351 aa)
NME2Nucleoside diphosphate kinase. (152 aa)
LOC112403992Nucleoside diphosphate kinase. (152 aa)
CES5ALOW QUALITY PROTEIN: carboxylesterase 5A. (455 aa)
LOC112404710UDP-glucuronosyltransferase 1-3-like isoform X1; Belongs to the UDP-glycosyltransferase family. (540 aa)
NME5Nucleoside diphosphate kinase homolog 5; Belongs to the NDK family. (212 aa)
GSTA4Glutathione S-transferase A4 isoform X1; Belongs to the GST superfamily. (240 aa)
LOC112406855Glutathione S-transferase A2; Belongs to the GST superfamily. (223 aa)
UMPSUridine 5'-monophosphate synthase. (480 aa)
DPYSDihydropyrimidinase isoform X1. (519 aa)
RRM2BRibonucleoside-diphosphate reductase subunit M2 B. (346 aa)
TPMTThiopurine S-methyltransferase. (245 aa)
MPOMyeloperoxidase. (718 aa)
LOC112408243Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (218 aa)
LOC112408499Arylamine N-acetyltransferase 1; Belongs to the arylamine N-acetyltransferase family. (290 aa)
NME4Nucleoside diphosphate kinase. (117 aa)
SPSB3SPRY domain-containing SOCS box protein 3 isoform X2. (377 aa)
MRPS3428S ribosomal protein S34, mitochondrial. (218 aa)
NME3Nucleoside diphosphate kinase. (85 aa)
PUSL1tRNA pseudouridine synthase. (356 aa)
TK1Thymidine kinase. (237 aa)
FAM78AProtein FAM78A. (283 aa)
LOC112411044LOW QUALITY PROTEIN: ribonucleoside-diphosphate reductase subunit M2-like. (423 aa)
LOC112411197LOW QUALITY PROTEIN: cytochrome P450 2E1; Belongs to the cytochrome P450 family. (492 aa)
UCK1Uridine-cytidine kinase 1 isoform X1. (283 aa)
IMPDH1Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (538 aa)
FAM78BProtein FAM78B. (261 aa)
UCK2Uridine-cytidine kinase 2 isoform X1. (290 aa)
LOC112412163Glutathione S-transferase theta-1-like. (111 aa)
FBXO41F-box only protein 41. (871 aa)
LOC112412315Glutathione S-transferase theta-4; Belongs to the GST superfamily. (241 aa)
LOC112412247Glutathione S-transferase theta-3-like isoform X1; Belongs to the GST superfamily. (240 aa)
UPP1Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (309 aa)
UPB1Beta-ureidopropionase. (384 aa)
CES1Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (496 aa)
LOC112402344Glutathione S-transferase P; Belongs to the GST superfamily. (208 aa)
RRM1Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (791 aa)
XDHXanthine dehydrogenase/oxidase isoform X1. (1334 aa)
SPSB2SPRY domain-containing SOCS box protein 2 isoform X1. (329 aa)
TK2Thymidine kinase 2, mitochondrial isoform X1. (264 aa)
CES2Cocaine esterase isoform X1; Belongs to the type-B carboxylesterase/lipase family. (761 aa)
MGST1Microsomal glutathione S-transferase 1. (155 aa)
LOC112393216Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (512 aa)
UPP2Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (320 aa)
LOC112392999Glutathione S-transferase omega-2-like; Belongs to the GST superfamily. (216 aa)
GSTO1Glutathione S-transferase omega-1; Belongs to the GST superfamily. (241 aa)
MGST2LOW QUALITY PROTEIN: microsomal glutathione S-transferase 2. (142 aa)
PFDN5Prefoldin subunit 5. (154 aa)
LOC112395053Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial-like. (164 aa)
IMPDH2Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (514 aa)
RRM2Ribonucleoside-diphosphate reductase subunit M2 isoform X1. (393 aa)
DALRD3DALR anticodon-binding domain-containing protein 3 isoform X1. (567 aa)
CMPK1UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (228 aa)
DUTDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial isoform X3. (227 aa)
PUS3tRNA pseudouridine(38/39) synthase. (479 aa)
PUS1tRNA pseudouridine synthase A isoform X1. (431 aa)
SLC12A1Solute carrier family 12 member 1. (1131 aa)
LOC112397404LOW QUALITY PROTEIN: UDP-glucuronosyltransferase 2B4-like. (303 aa)
LOC112397401LOW QUALITY PROTEIN: uncharacterized protein LOC112397401. (665 aa)
GMPSGMP synthase [glutamine-hydrolyzing] isoform X1. (741 aa)
NME7Nucleoside diphosphate kinase 7 isoform X1; Belongs to the NDK family. (400 aa)
LOC112397411UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (529 aa)
LOC112397818Glutathione S-transferase Mu 3. (225 aa)
MGST3Microsomal glutathione S-transferase 3. (152 aa)
FBXL20F-box/LRR-repeat protein 20 isoform X1. (438 aa)
FBXL2F-box/LRR-repeat protein 2. (423 aa)
ITPAInosine triphosphate pyrophosphatase isoform X1. (208 aa)
LOC112399556Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (218 aa)
GUSBBeta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family. (652 aa)
HPRT1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (176 aa)
GDAP1L1Ganglioside-induced differentiation-associated protein 1-like 1 isoform X1. (389 aa)
SPSB1SPRY domain-containing SOCS box protein 1. (273 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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