STRINGSTRING
CARTPT CARTPT CLPTM1 CLPTM1 PNMA8B PNMA8B NIPSNAP1 NIPSNAP1 EHHADH EHHADH LOC112415038 LOC112415038 PGLS PGLS ACAT1 ACAT1 IDH2 IDH2 KIFC1 KIFC1 MUT MUT URB2 URB2 HK1 HK1 HKDC1 HKDC1 HAO2 HAO2 GOT1L1 GOT1L1 HAO1 HAO1 PHGDH PHGDH HADHA HADHA LOC112412850 LOC112412850 PGK1 PGK1 AGXT AGXT MTCL1 MTCL1 ME3 ME3 CPS1 CPS1 ECHS1 ECHS1 PARP6 PARP6 ADPGK ADPGK PKM PKM PRPSAP1 PRPSAP1 ACOX1 ACOX1 WRAP73 WRAP73 LOC112409743 LOC112409743 PGP PGP SETD3 SETD3 KIAA0408 KIAA0408 SETD4 SETD4 SOGA3 SOGA3 PFKL PFKL ME2 ME2 ME1 ME1 SDHC SDHC PXDN PXDN IDH3G IDH3G ENO4 ENO4 EPS8L1 EPS8L1 LOC112406290 LOC112406290 LOC112406271 LOC112406271 SUCLA2 SUCLA2 ESD ESD SDHD SDHD PFKP PFKP IDH3A IDH3A DLAT DLAT FBP1 FBP1 LOC112405304 LOC112405304 ACO1 ACO1 MDH1 MDH1 FBP2 FBP2 IDNK IDNK SHMT1 SHMT1 LOC112405303 LOC112405303 PRPSAP2 PRPSAP2 CENPV CENPV ACSS1 ACSS1 CAT CAT GPT2 GPT2 JADE2 JADE2 HK2 HK2 GOT2 GOT2 PGD PGD H6PD H6PD PPP1R32 PPP1R32 PC PC BBS1 BBS1 MTHFR MTHFR SDHB SDHB ENO1 ENO1 TKFC TKFC EPS8L2 EPS8L2 TALDO1 TALDO1 ACAT2 ACAT2 SDHAF2 SDHAF2 GCK GCK PKLR PKLR PGAM2 PGAM2 KIFC3 KIFC3 SUCLG2 SUCLG2 PDHB PDHB PCCB PCCB GLYCTK GLYCTK TKT TKT G6PD G6PD MDH2 MDH2 OGDH OGDH ZMIZ2 ZMIZ2 LOC112399194 LOC112399194 TKTL1 TKTL1 JADE1 JADE1 ALDOA ALDOA ACOX3 ACOX3 NIPSNAP2 NIPSNAP2 ACOXL ACOXL PSPH PSPH JADE3 JADE3 ACSS2 ACSS2 MCEE MCEE SUCLG1 SUCLG1 RPIA RPIA IDH3B IDH3B RGN RGN SOGA1 SOGA1 MYCBPAP MYCBPAP PNPLA8 PNPLA8 EPS8L3 EPS8L3 HK3 HK3 ACADS ACADS DLD DLD KIFC2 KIFC2 SDS SDS FH FH SDSL SDSL GPT GPT PCCA PCCA PPHLN1 PPHLN1 PARP8 PARP8 ZMIZ1 ZMIZ1 LOC112395668 LOC112395668 OGDHL OGDHL NOC3L NOC3L LOC112395635 LOC112395635 ALDH6A1 ALDH6A1 PDHA1 PDHA1 PRPS1L1 PRPS1L1 IDH1 IDH1 AMT AMT RPE RPE MDH1B MDH1B SHMT2 SHMT2 PRPS1 PRPS1 METTL1 METTL1 PFKM PFKM ENO3 ENO3 CS CS TSR1 TSR1 DLST DLST ACO2 ACO2 PDHA2 PDHA2 LOC112393724 LOC112393724 TKTL2 TKTL2 GOT1 GOT1 SPAG5 SPAG5 LOC112393780 LOC112393780 ALDOC ALDOC PGAM1 PGAM1 GCSH GCSH ALDOB ALDOB GPI GPI ENO2 ENO2 EPS8 EPS8 HIBCH HIBCH GLDC GLDC GAPDH GAPDH TPI1 TPI1 CLPTM1L CLPTM1L RBM45 RBM45 SDHA SDHA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CARTPTCocaine- and amphetamine-regulated transcript protein. (116 aa)
CLPTM1Cleft lip and palate transmembrane protein 1. (680 aa)
PNMA8BLOW QUALITY PROTEIN: paraneoplastic antigen-like protein 8B. (764 aa)
NIPSNAP1Protein NipSnap homolog 1. (284 aa)
EHHADHPeroxisomal bifunctional enzyme. (723 aa)
LOC112415038Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (173 aa)
PGLS6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (258 aa)
ACAT1acetyl-CoA acetyltransferase, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family. (427 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (452 aa)
KIFC1Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (672 aa)
MUTmethylmalonyl-CoA mutase, mitochondrial. (750 aa)
URB2Unhealthy ribosome biogenesis protein 2 homolog isoform X1. (1516 aa)
HK1Hexokinase-1 isoform X2. (935 aa)
HKDC1Putative hexokinase HKDC1 isoform X1. (917 aa)
HAO2Hydroxyacid oxidase 2. (353 aa)
GOT1L1Putative aspartate aminotransferase, cytoplasmic 2. (424 aa)
HAO1Hydroxyacid oxidase 1 isoform X1. (385 aa)
PHGDHD-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (533 aa)
HADHATrifunctional enzyme subunit alpha, mitochondrial; Belongs to the enoyl-CoA hydratase/isomerase family. (763 aa)
LOC112412850LOW QUALITY PROTEIN: isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial-like. (387 aa)
PGK1Phosphoglycerate kinase. (417 aa)
AGXTSerine--pyruvate aminotransferase. (414 aa)
MTCL1Microtubule cross-linking factor 1 isoform X1. (1615 aa)
ME3Malic enzyme. (604 aa)
CPS1Carbamoyl-phosphate synthase [ammonia], mitochondrial. (1500 aa)
ECHS1enoyl-CoA hydratase, mitochondrial; Belongs to the enoyl-CoA hydratase/isomerase family. (293 aa)
PARP6Poly [ADP-ribose] polymerase. (631 aa)
ADPGKADP-dependent glucokinase isoform X1. (496 aa)
PKMPyruvate kinase; Belongs to the pyruvate kinase family. (531 aa)
PRPSAP1Phosphoribosyl pyrophosphate synthase-associated protein 1 isoform X1. (400 aa)
ACOX1Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (661 aa)
WRAP73WD repeat-containing protein WRAP73 isoform X1. (460 aa)
LOC112409743Ribose-phosphate pyrophosphokinase 2. (251 aa)
PGPGlycerol-3-phosphate phosphatase. (396 aa)
SETD3Protein-histidine N-methyltransferase. (601 aa)
KIAA0408Uncharacterized protein KIAA0408 homolog. (693 aa)
SETD4SET domain-containing protein 4 isoform X1. (440 aa)
SOGA3Protein SOGA3. (947 aa)
PFKLATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (732 aa)
ME2Malic enzyme. (584 aa)
ME1Malic enzyme. (496 aa)
SDHCSuccinate dehydrogenase cytochrome b560 subunit, mitochondrial isoform X1. (169 aa)
PXDNPeroxidasin homolog. (1295 aa)
IDH3GIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (392 aa)
ENO4Enolase 4. (616 aa)
EPS8L1Epidermal growth factor receptor kinase substrate 8-like protein 1. (713 aa)
LOC112406290S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (374 aa)
LOC112406271LOW QUALITY PROTEIN: ribulose-phosphate 3-epimerase-like. (327 aa)
SUCLA2Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (463 aa)
ESDS-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (282 aa)
SDHDSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (159 aa)
PFKPATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (791 aa)
IDH3AIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (366 aa)
DLATAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (647 aa)
FBP1Fructose-1,6-bisphosphatase 1; Belongs to the FBPase class 1 family. (338 aa)
LOC112405304Protein NipSnap homolog 3A. (247 aa)
ACO1Cytoplasmic aconitate hydratase isoform X1; Belongs to the aconitase/IPM isomerase family. (906 aa)
MDH1Malate dehydrogenase. (334 aa)
FBP2Fructose-1,6-bisphosphatase isozyme 2; Belongs to the FBPase class 1 family. (339 aa)
IDNKGluconokinase; Belongs to the gluconokinase GntK/GntV family. (188 aa)
SHMT1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (484 aa)
LOC112405303Protein NipSnap homolog 3A-like isoform X1. (247 aa)
PRPSAP2Phosphoribosyl pyrophosphate synthase-associated protein 2 isoform X1. (369 aa)
CENPVCentromere protein V. (167 aa)
ACSS1Acetyl-coenzyme A synthetase. (518 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa)
GPT2Alanine aminotransferase 2. (523 aa)
JADE2E3 ubiquitin-protein ligase Jade-2 isoform X1. (827 aa)
HK2Hexokinase-2. (917 aa)
GOT2Aspartate aminotransferase. (430 aa)
PGD6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (483 aa)
H6PDGDH/6PGL endoplasmic bifunctional protein isoform X1. (840 aa)
PPP1R32Protein phosphatase 1 regulatory subunit 32. (498 aa)
PCPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1190 aa)
BBS1Bardet-Biedl syndrome 1 protein isoform X1. (593 aa)
MTHFRMethylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (696 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (280 aa)
ENO1Alpha-enolase. (444 aa)
TKFCtriokinase/FMN cyclase isoform X1. (577 aa)
EPS8L2Epidermal growth factor receptor kinase substrate 8-like protein 2. (451 aa)
TALDO1Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (319 aa)
ACAT2acetyl-CoA acetyltransferase, cytosolic; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
SDHAF2Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer. (185 aa)
GCKPhosphotransferase. (537 aa)
PKLRPyruvate kinase; Belongs to the pyruvate kinase family. (574 aa)
PGAM2Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (253 aa)
KIFC3Kinesin-like protein KIFC3 isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1033 aa)
SUCLG2Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (432 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (359 aa)
PCCBpropionyl-CoA carboxylase beta chain, mitochondrial. (540 aa)
GLYCTKGlycerate kinase isoform X1. (523 aa)
TKTTransketolase. (623 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase. (614 aa)
MDH2Malate dehydrogenase. (338 aa)
OGDH2-oxoglutarate dehydrogenase, mitochondrial isoform X3. (1039 aa)
ZMIZ2Zinc finger MIZ domain-containing protein 2 isoform X1. (933 aa)
LOC112399194Keratin-associated protein 10-10-like. (91 aa)
TKTL1Transketolase-like protein 1. (541 aa)
JADE1Protein Jade-1 isoform X1. (858 aa)
ALDOAFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
ACOX3Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (720 aa)
NIPSNAP2Protein NipSnap homolog 2. (218 aa)
ACOXLLOW QUALITY PROTEIN: acyl-coenzyme A oxidase-like protein. (537 aa)
PSPHPhosphoserine phosphatase. (225 aa)
JADE3Protein Jade-3 isoform X1. (834 aa)
ACSS2Acetyl-coenzyme A synthetase, cytoplasmic isoform X1. (714 aa)
MCEEmethylmalonyl-CoA epimerase, mitochondrial. (176 aa)
SUCLG1Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (346 aa)
RPIARibose-5-phosphate isomerase isoform X1. (344 aa)
IDH3BIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (385 aa)
RGNRegucalcin. (301 aa)
SOGA1Protein SOGA1 isoform X2. (1468 aa)
MYCBPAPMYCBP-associated protein. (955 aa)
PNPLA8Calcium-independent phospholipase A2-gamma isoform X1. (784 aa)
EPS8L3Epidermal growth factor receptor kinase substrate 8-like protein 3. (606 aa)
HK3Hexokinase-3 isoform X1. (989 aa)
ACADSShort-chain specific acyl-CoA dehydrogenase, mitochondrial isoform X1. (412 aa)
DLDDihydrolipoyl dehydrogenase. (509 aa)
KIFC2Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (809 aa)
SDSL-serine dehydratase/L-threonine deaminase. (328 aa)
FHFumarate hydratase, mitochondrial. (510 aa)
SDSLSerine dehydratase-like. (329 aa)
GPTLOW QUALITY PROTEIN: alanine aminotransferase 1. (489 aa)
PCCApropionyl-CoA carboxylase alpha chain, mitochondrial. (730 aa)
PPHLN1Periphilin-1 isoform X1. (374 aa)
PARP8Poly [ADP-ribose] polymerase. (929 aa)
ZMIZ1Zinc finger MIZ domain-containing protein 1. (1065 aa)
LOC112395668Phosphoserine aminotransferase. (370 aa)
OGDHL2-oxoglutarate dehydrogenase-like, mitochondrial isoform X1. (1018 aa)
NOC3LNucleolar complex protein 3 homolog. (820 aa)
LOC112395635Glycine cleavage system H protein, mitochondrial-like. (129 aa)
ALDH6A1Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial. (479 aa)
PDHA1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (390 aa)
PRPS1L1LOW QUALITY PROTEIN: ribose-phosphate pyrophosphokinase 3. (316 aa)
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
AMTAminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (403 aa)
RPERibulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (239 aa)
MDH1BPutative malate dehydrogenase 1B isoform X1. (505 aa)
SHMT2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (504 aa)
PRPS1Ribose-phosphate pyrophosphokinase 1. (318 aa)
METTL1tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. (266 aa)
PFKMATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (851 aa)
ENO3Beta-enolase isoform X1. (546 aa)
CSCitrate synthase; Belongs to the citrate synthase family. (466 aa)
TSR1pre-rRNA-processing protein TSR1 homolog isoform X1. (804 aa)
DLSTannotation not available (455 aa)
ACO2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (781 aa)
PDHA2annotation not available (387 aa)
LOC112393724S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (374 aa)
TKTL2LOW QUALITY PROTEIN: transketolase-like protein 2. (751 aa)
GOT1Aspartate aminotransferase. (413 aa)
SPAG5Sperm-associated antigen 5. (1195 aa)
LOC112393780Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (226 aa)
ALDOCFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
PGAM1Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (254 aa)
GCSHGlycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (207 aa)
ALDOBFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
GPIGlucose-6-phosphate isomerase; Belongs to the GPI family. (558 aa)
ENO2Gamma-enolase. (434 aa)
EPS8Epidermal growth factor receptor kinase substrate 8 isoform X1. (835 aa)
HIBCH3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (386 aa)
GLDCGlycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1020 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
TPI1Triosephosphate isomerase. (286 aa)
CLPTM1LCleft lip and palate transmembrane protein 1-like protein isoform X1. (539 aa)
RBM45RNA-binding protein 45. (474 aa)
SDHASuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (665 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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