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PAH PAH LGSN LGSN TPI1 TPI1 GAPDH GAPDH CMTM3 CMTM3 LOC112391475 LOC112391475 ASNSD1 ASNSD1 BCAT1 BCAT1 EPS8 EPS8 CMTM4 CMTM4 LOC112392032 LOC112392032 ENO2 ENO2 CTH CTH ALDOB ALDOB PGAM1 PGAM1 ALDOC ALDOC LOC112393780 LOC112393780 SPAG5 SPAG5 GOT1 GOT1 TKTL2 TKTL2 ACO2 ACO2 TMED8 TMED8 NOXRED1 NOXRED1 CS CS ENO3 ENO3 PFKM PFKM METTL1 METTL1 PRPS1 PRPS1 SHMT2 SHMT2 RPE RPE IDH1 IDH1 PRPS1L1 PRPS1L1 LOC112395668 LOC112395668 MAT1A MAT1A PARP8 PARP8 PPHLN1 PPHLN1 GPT GPT PYCR3 PYCR3 SDSL SDSL SDS SDS MAL2 MAL2 EPS8L3 EPS8L3 MYADM MYADM PNPLA8 PNPLA8 CMTM8 CMTM8 CMTM7 CMTM7 MYCBPAP MYCBPAP CMTM6 CMTM6 THNSL2 THNSL2 IDH3B IDH3B RPIA RPIA PSPH PSPH CRYM CRYM ATAD1 ATAD1 MALL MALL ASL ASL MAT2A MAT2A ALDOA ALDOA TKTL1 TKTL1 LOC112399194 LOC112399194 PLP2 PLP2 TKT TKT ACY1 ACY1 PLLP PLLP PGAM2 PGAM2 TFB1M TFB1M PKLR PKLR ARG2 ARG2 TALDO1 TALDO1 EPS8L2 EPS8L2 ENO1 ENO1 PC PC ALDH18A1 ALDH18A1 GOT2 GOT2 EIF2D EIF2D GPT2 GPT2 PYCR2 PYCR2 CMTM5 CMTM5 PRPSAP2 PRPSAP2 MAT2B MAT2B SHMT1 SHMT1 ACO1 ACO1 IDH3A IDH3A PFKP PFKP LOC112406271 LOC112406271 EPS8L1 EPS8L1 ENO4 ENO4 IDH3G IDH3G SRFBP1 SRFBP1 PFKL PFKL ARG1 ARG1 GLUL GLUL CBS CBS LOC112409743 LOC112409743 WRAP73 WRAP73 PRPSAP1 PRPSAP1 PYCR1 PYCR1 NAGS NAGS MTR MTR LOC112410451 LOC112410451 PKM PKM PARP6 PARP6 MYADML2 MYADML2 ASS1 ASS1 CPS1 CPS1 PGK1 PGK1 LOC112412850 LOC112412850 OTC OTC PHGDH PHGDH GOT1L1 GOT1L1 DIMT1 DIMT1 THNSL1 THNSL1 LOC112412836 LOC112412836 TFB2M TFB2M IDH2 IDH2 LOC112414172 LOC112414172 ASNS ASNS LOC112415649 LOC112415649 BCAT2 BCAT2 PNMA8B PNMA8B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PAHPhenylalanine-4-hydroxylase. (452 aa)
LGSNLengsin; Belongs to the glutamine synthetase family. (573 aa)
TPI1Triosephosphate isomerase. (286 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
CMTM3CKLF-like MARVEL transmembrane domain-containing protein 3. (236 aa)
LOC112391475CKLF-like MARVEL transmembrane domain-containing protein 2. (241 aa)
ASNSD1Asparagine synthetase domain-containing protein 1. (643 aa)
BCAT1Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (458 aa)
EPS8Epidermal growth factor receptor kinase substrate 8 isoform X1. (835 aa)
CMTM4CKLF-like MARVEL transmembrane domain-containing protein 4. (208 aa)
LOC112392032CKLF-like MARVEL transmembrane domain-containing protein 1. (186 aa)
ENO2Gamma-enolase. (434 aa)
CTHCystathionine gamma-lyase isoform X1. (436 aa)
ALDOBFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
PGAM1Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (254 aa)
ALDOCFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
LOC112393780Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (226 aa)
SPAG5Sperm-associated antigen 5. (1195 aa)
GOT1Aspartate aminotransferase. (413 aa)
TKTL2LOW QUALITY PROTEIN: transketolase-like protein 2. (751 aa)
ACO2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (781 aa)
TMED8Protein TMED8 isoform X1. (259 aa)
NOXRED1NADP-dependent oxidoreductase domain-containing protein 1. (382 aa)
CSCitrate synthase; Belongs to the citrate synthase family. (466 aa)
ENO3Beta-enolase isoform X1. (546 aa)
PFKMATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (851 aa)
METTL1tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. (266 aa)
PRPS1Ribose-phosphate pyrophosphokinase 1. (318 aa)
SHMT2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (504 aa)
RPERibulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (239 aa)
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
PRPS1L1LOW QUALITY PROTEIN: ribose-phosphate pyrophosphokinase 3. (316 aa)
LOC112395668Phosphoserine aminotransferase. (370 aa)
MAT1AS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (396 aa)
PARP8Poly [ADP-ribose] polymerase. (929 aa)
PPHLN1Periphilin-1 isoform X1. (374 aa)
GPTLOW QUALITY PROTEIN: alanine aminotransferase 1. (489 aa)
PYCR3Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (277 aa)
SDSLSerine dehydratase-like. (329 aa)
SDSL-serine dehydratase/L-threonine deaminase. (328 aa)
MAL2Protein MAL2. (176 aa)
EPS8L3Epidermal growth factor receptor kinase substrate 8-like protein 3. (606 aa)
MYADMMyeloid-associated differentiation marker. (320 aa)
PNPLA8Calcium-independent phospholipase A2-gamma isoform X1. (784 aa)
CMTM8CKLF-like MARVEL transmembrane domain-containing protein 8. (279 aa)
CMTM7CKLF-like MARVEL transmembrane domain-containing protein 7. (175 aa)
MYCBPAPMYCBP-associated protein. (955 aa)
CMTM6CKLF-like MARVEL transmembrane domain-containing protein 6. (178 aa)
THNSL2Threonine synthase-like 2. (484 aa)
IDH3BIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (385 aa)
RPIARibose-5-phosphate isomerase isoform X1. (344 aa)
PSPHPhosphoserine phosphatase. (225 aa)
CRYMKetimine reductase mu-crystallin isoform X1. (314 aa)
ATAD1ATPase family AAA domain-containing protein 1; Belongs to the AAA ATPase family. (380 aa)
MALLMAL-like protein. (153 aa)
ASLArgininosuccinate lyase. (464 aa)
MAT2AS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (395 aa)
ALDOAFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
TKTL1Transketolase-like protein 1. (541 aa)
LOC112399194Keratin-associated protein 10-10-like. (91 aa)
PLP2Proteolipid protein 2. (152 aa)
TKTTransketolase. (623 aa)
ACY1Aminoacylase-1. (408 aa)
PLLPPlasmolipin. (238 aa)
PGAM2Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (253 aa)
TFB1MrRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (338 aa)
PKLRPyruvate kinase; Belongs to the pyruvate kinase family. (574 aa)
ARG2Arginase. (354 aa)
TALDO1Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (319 aa)
EPS8L2Epidermal growth factor receptor kinase substrate 8-like protein 2. (451 aa)
ENO1Alpha-enolase. (444 aa)
PCPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1190 aa)
ALDH18A1Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. (795 aa)
GOT2Aspartate aminotransferase. (430 aa)
EIF2DEukaryotic translation initiation factor 2D isoform X1. (584 aa)
GPT2Alanine aminotransferase 2. (523 aa)
PYCR2Pyrroline-5-carboxylate reductase 2. (117 aa)
CMTM5CKLF-like MARVEL transmembrane domain-containing protein 5. (155 aa)
PRPSAP2Phosphoribosyl pyrophosphate synthase-associated protein 2 isoform X1. (369 aa)
MAT2BMethionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. (344 aa)
SHMT1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (484 aa)
ACO1Cytoplasmic aconitate hydratase isoform X1; Belongs to the aconitase/IPM isomerase family. (906 aa)
IDH3AIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (366 aa)
PFKPATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (791 aa)
LOC112406271LOW QUALITY PROTEIN: ribulose-phosphate 3-epimerase-like. (327 aa)
EPS8L1Epidermal growth factor receptor kinase substrate 8-like protein 1. (713 aa)
ENO4Enolase 4. (616 aa)
IDH3GIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (392 aa)
SRFBP1Serum response factor-binding protein 1. (428 aa)
PFKLATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (732 aa)
ARG1Arginase. (322 aa)
GLULGlutamine synthetase. (381 aa)
CBSCystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (562 aa)
LOC112409743Ribose-phosphate pyrophosphokinase 2. (251 aa)
WRAP73WD repeat-containing protein WRAP73 isoform X1. (460 aa)
PRPSAP1Phosphoribosyl pyrophosphate synthase-associated protein 1 isoform X1. (400 aa)
PYCR1Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (320 aa)
NAGSN-acetylglutamate synthase, mitochondrial. (368 aa)
MTRMethionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1274 aa)
LOC112410451LOW QUALITY PROTEIN: probable low-specificity L-threonine aldolase 2. (388 aa)
PKMPyruvate kinase; Belongs to the pyruvate kinase family. (531 aa)
PARP6Poly [ADP-ribose] polymerase. (631 aa)
MYADML2Myeloid-associated differentiation marker-like protein 2. (307 aa)
ASS1Argininosuccinate synthase. (412 aa)
CPS1Carbamoyl-phosphate synthase [ammonia], mitochondrial. (1500 aa)
PGK1Phosphoglycerate kinase. (417 aa)
LOC112412850LOW QUALITY PROTEIN: isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial-like. (387 aa)
OTCOrnithine carbamoyltransferase, mitochondrial. (143 aa)
PHGDHD-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (533 aa)
GOT1L1Putative aspartate aminotransferase, cytoplasmic 2. (424 aa)
DIMT1rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (317 aa)
THNSL1Threonine synthase-like 1. (743 aa)
LOC112412836Ornithine carbamoyltransferase, mitochondrial-like; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (161 aa)
TFB2MrRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (394 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (452 aa)
LOC112414172LOW QUALITY PROTEIN: myeloid-associated differentiation marker-like. (313 aa)
ASNSAsparagine synthetase [glutamine-hydrolyzing]. (561 aa)
LOC112415649LOW QUALITY PROTEIN: ATPase family AAA domain-containing protein 1-like. (498 aa)
BCAT2LOW QUALITY PROTEIN: branched-chain-amino-acid aminotransferase, mitochondrial. (528 aa)
PNMA8BLOW QUALITY PROTEIN: paraneoplastic antigen-like protein 8B. (764 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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