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| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1238 aa) |
| | LOC112398354 | LOW QUALITY PROTEIN: serine/threonine-protein kinase Sgk1-like. (374 aa) |
| | TSSK3 | Testis-specific serine/threonine-protein kinase 3. (268 aa) |
| | FBXO32 | F-box only protein 32. (355 aa) |
| | REM2 | GTP-binding protein REM 2 isoform X1. (388 aa) |
| | PLK5 | LOW QUALITY PROTEIN: inactive serine/threonine-protein kinase PLK5. (561 aa) |
| | TNFSF10 | Tumor necrosis factor ligand superfamily member. (288 aa) |
| | SUCO | SUN domain-containing ossification factor isoform X1. (1249 aa) |
| | IRS1 | Insulin receptor substrate 1. (1248 aa) |
| | GADD45B | Growth arrest and DNA damage-inducible protein GADD45 beta. (160 aa) |
| | STK11 | Serine/threonine-protein kinase STK11 isoform X1. (546 aa) |
| | S1PR4 | Sphingosine 1-phosphate receptor 4. (489 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | IL6 | Interleukin-6. (208 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (376 aa) |
| | TGFB3 | Transforming growth factor beta-3. (456 aa) |
| | SLC35E3 | Solute carrier family 35 member E3 isoform X1. (313 aa) |
| | EP300 | Histone acetyltransferase p300. (2399 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (491 aa) |
| | NLK | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa) |
| | CDK2 | Cyclin-dependent kinase 2 isoform X1; Belongs to the protein kinase superfamily. (346 aa) |
| | PRKAG1 | 5'-AMP-activated protein kinase subunit gamma-1 isoform X1. (333 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (424 aa) |
| | AGAP2 | arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 isoform X1. (836 aa) |
| | CCNB2 | G2/mitotic-specific cyclin-B2 isoform X1; Belongs to the cyclin family. (398 aa) |
| | GADD45A | Growth arrest and DNA damage-inducible protein GADD45 alpha. (165 aa) |
| | SETD7 | Histone-lysine N-methyltransferase SETD7 isoform X1. (407 aa) |
| | CHUK | Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (744 aa) |
| | GABARAPL2 | Gamma-aminobutyric acid receptor-associated protein-like 2 isoform X1. (145 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (438 aa) |
| | LOC112393165 | E3 ubiquitin-protein ligase Arkadia-like isoform X1. (216 aa) |
| | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (376 aa) |
| | FOXJ2 | LOW QUALITY PROTEIN: forkhead box protein J2. (510 aa) |
| | RRAD | GTP-binding protein RAD isoform X1. (352 aa) |
| | CCND2 | G1/S-specific cyclin-D2; Belongs to the cyclin family. (289 aa) |
| | GABARAPL1 | Gamma-aminobutyric acid receptor-associated protein-like 1. (117 aa) |
| | SOS2 | Son of sevenless homolog 2 isoform X1. (1272 aa) |
| | LOC112392089 | RAC-alpha serine/threonine-protein kinase. (138 aa) |
| | LOC112392044 | Ubiquitin-like protein ATG12. (54 aa) |
| | PRMT8 | Protein arginine N-methyltransferase 8 isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (394 aa) |
| | CDKN1B | Cyclin-dependent kinase inhibitor 1B. (198 aa) |
| | IGF1R | Tyrosine-protein kinase receptor. (1368 aa) |
| | KRAS | GTPase KRas isoform X3. (227 aa) |
| | FASLG | Tumor necrosis factor ligand superfamily member 6; Belongs to the tumor necrosis factor family. (262 aa) |
| | IGF1 | Insulin-like growth factor I isoform X1. (208 aa) |
| | GABARAP | Gamma-aminobutyric acid receptor-associated protein. (117 aa) |
| | BCL6B | B-cell CLL/lymphoma 6 member B protein isoform X1. (479 aa) |
| | GADD45G | Growth arrest and DNA damage-inducible protein GADD45 gamma. (159 aa) |
| | SLC2A4 | Solute carrier family 2, facilitated glucose transporter member 4 isoform X1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (603 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1078 aa) |
| | ARAF | Serine/threonine-protein kinase A-Raf isoform X1. (625 aa) |
| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa) |
| | IL10 | Interleukin-10. (178 aa) |
| | PCK1 | Phosphoenolpyruvate carboxykinase, cytosolic [GTP]. (622 aa) |
| | S1PR1 | Sphingosine 1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (382 aa) |
| | RASGEF1A | ras-GEF domain-containing family member 1A. (533 aa) |
| | RAG2 | V(D)J recombination-activating protein 2. (527 aa) |
| | CAT | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa) |
| | RAG1 | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1043 aa) |
| | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa) |
| | SOS1 | Son of sevenless homolog 1 isoform X1. (1350 aa) |
| | TSSK4 | Testis-specific serine/threonine-protein kinase 4. (338 aa) |
| | PCK2 | Phosphoenolpyruvate carboxykinase [GTP], mitochondrial isoform X1. (650 aa) |
| | GRAP | GRB2-related adapter protein. (217 aa) |
| | CCNG2 | cyclin-G2; Belongs to the cyclin family. (344 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase. (531 aa) |
| | PRKAG2 | 5'-AMP-activated protein kinase subunit gamma-2 isoform X1. (566 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (559 aa) |
| | SKP2 | S-phase kinase-associated protein 2 isoform X1. (436 aa) |
| | IL7R | Interleukin-7 receptor subunit alpha. (459 aa) |
| | IRS2 | Insulin receptor substrate 2. (702 aa) |
| | FOXG1 | Forkhead box protein G1. (662 aa) |
| | FOXO3 | Forkhead box protein O3. (672 aa) |
| | FOXO1 | Forkhead box protein O1. (511 aa) |
| | LOC112406592 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2-like isoform X1. (598 aa) |
| | RNF6 | E3 ubiquitin-protein ligase RNF6 isoform X1. (663 aa) |
| | HOMER1 | Homer protein homolog 1 isoform X1. (354 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | CCNB1 | G2/mitotic-specific cyclin-B1; Belongs to the cyclin family. (433 aa) |
| | RAF1 | RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (462 aa) |
| | G6PC2 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (355 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (599 aa) |
| | AKT1 | RAC-alpha serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (339 aa) |
| | LOC112408488 | Serine/threonine-protein kinase B-raf-like. (250 aa) |
| | FOXO4 | Forkhead box protein O4. (512 aa) |
| | LOC112409111 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (445 aa) |
| | PDPK1 | 3-phosphoinositide-dependent protein kinase 1 isoform X1. (531 aa) |
| | PRKAB1 | 5'-AMP-activated protein kinase subunit beta-1. (270 aa) |
| | USP7 | Ubiquitin carboxyl-terminal hydrolase 7 isoform X2; Belongs to the peptidase C19 family. (1055 aa) |
| | CREBBP | CREB-binding protein. (2443 aa) |
| | FBXO25 | F-box only protein 25 isoform X1. (517 aa) |
| | G6PC3 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (346 aa) |
| | CDK3 | Cyclin-dependent kinase 3; Belongs to the protein kinase superfamily. (313 aa) |
| | LOC112410850 | Casein kinase I isoform X1; Belongs to the protein kinase superfamily. (416 aa) |
| | GRB2 | Growth factor receptor-bound protein 2. (217 aa) |
| | MYO9A | Unconventional myosin-IXa isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2663 aa) |
| | LOC112410685 | E3 ubiquitin-protein ligase Arkadia isoform X1. (796 aa) |
| | BNIP3 | BCL2/adenovirus E1B 19 kDa protein-interacting protein 3. (196 aa) |
| | PLK3 | Serine/threonine-protein kinase PLK. (647 aa) |
| | PRKAG3 | 5'-AMP-activated protein kinase subunit gamma-3. (464 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (343 aa) |
| | LDLRAD4 | LOW QUALITY PROTEIN: low-density lipoprotein receptor class A domain-containing protein 4. (322 aa) |
| | TSSK2 | LOW QUALITY PROTEIN: testis-specific serine/threonine-protein kinase 2; Belongs to the protein kinase superfamily. (363 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (464 aa) |
| | TSSK1B | Testis-specific serine/threonine-protein kinase 1; Belongs to the protein kinase superfamily. (368 aa) |
| | PRMT3 | Protein arginine N-methyltransferase 3 isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (530 aa) |
| | PRKAB2 | 5'-AMP-activated protein kinase subunit beta-2. (272 aa) |
| | CSDE1 | Cold shock domain-containing protein E1 isoform X1. (798 aa) |
| | NRAS | GTPase NRas. (189 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (821 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1156 aa) |
| | PLK2 | Serine/threonine-protein kinase PLK. (685 aa) |
| | GEM | GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (317 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (366 aa) |
| | CDKN1A | Cyclin-dependent kinase inhibitor 1. (164 aa) |
| | HOMER2 | Homer protein homolog 2 isoform X1. (298 aa) |
| | SIRT1 | NAD-dependent protein deacetylase sirtuin-1 isoform X1. (557 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3064 aa) |
| | BCL6 | B-cell lymphoma 6 protein. (706 aa) |
| | RASGEF1B | ras-GEF domain-containing family member 1B. (472 aa) |
| | KLF2 | Krueppel-like factor 2. (222 aa) |
| | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa) |
| | TSSK6 | Testis-specific serine/threonine-protein kinase 6; Belongs to the protein kinase superfamily. (273 aa) |
| | CDKN2B | Cyclin-dependent kinase 4 inhibitor B. (131 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa) |
| | MYO9B | Unconventional myosin-IXb isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2183 aa) |
| | HOMER3 | Homer protein homolog 3. (360 aa) |
| | CNTD2 | Cyclin N-terminal domain-containing protein 2 isoform X2; Belongs to the cyclin family. (308 aa) |
| | PRMT1 | Protein arginine N-methyltransferase 1 isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (371 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | ERAS | GTPase ERas. (225 aa) |
| | PMEPA1 | Protein TMEPAI isoform X1. (269 aa) |
| | INS | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa) |
| | CCND1 | G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa) |
| | HRAS | GTPase HRas isoform X1. (189 aa) |
| | IRS4 | LOW QUALITY PROTEIN: insulin receptor substrate 4. (1261 aa) |
| | SNAPIN | SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa) |
| | GRM1 | Metabotropic glutamate receptor 1 isoform X1. (1194 aa) |
| | SOD2 | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (232 aa) |
| | RBL2 | Retinoblastoma-like protein 2 isoform X1. (1141 aa) |
| | RASL11B | Ras-like protein family member 11B. (248 aa) |
| | CDKN2D | Cyclin-dependent kinase 4 inhibitor D. (166 aa) |
| | STK4 | Serine/threonine-protein kinase 4 isoform X1. (487 aa) |
| | SGK2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (383 aa) |
| | INSR | Tyrosine-protein kinase receptor. (1382 aa) |
| | MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2. (303 aa) |
| | LOC112399963 | LOW QUALITY PROTEIN: insulin receptor substrate 1-like. (561 aa) |
| | G6PC | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa) |
| | LOC112400438 | Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa) |
| | PLK4 | Serine/threonine-protein kinase PLK4 isoform X1. (971 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | MAPK3 | Mitogen-activated protein kinase 3. (265 aa) |
| | PLK1 | Serine/threonine-protein kinase PLK. (597 aa) |
| | CCNB3 | G2/mitotic-specific cyclin-B3; Belongs to the cyclin family. (1245 aa) |
| | FOXO6 | Forkhead box protein O6. (374 aa) |
| | FOXJ3 | Forkhead box protein J3 isoform X1. (622 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa) |
| | ATG12 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (88 aa) |
| | TMEM232 | LOW QUALITY PROTEIN: transmembrane protein 232. (676 aa) |
| | BCL2L11 | Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (196 aa) |
| | LOC112398198 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (490 aa) |
| | BRAF | Serine/threonine-protein kinase B-raf isoform X1. (581 aa) |
| | REM1 | GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (300 aa) |
