STRINGSTRING
BCL2L13 BCL2L13 TBC1D15 TBC1D15 USP4 USP4 USP19 USP19 TOMM7 TOMM7 CITED4 CITED4 ATF4 ATF4 MAPK8 MAPK8 LY6G5B LY6G5B CSNK2B CSNK2B ULK1 ULK1 LOC112396539 LOC112396539 BECN2 BECN2 CITED2 CITED2 PGAM5 PGAM5 USP30 USP30 AGFG1 AGFG1 REM2 REM2 NPAS3 NPAS3 NBR1 NBR1 CSNK2A1 CSNK2A1 REM1 REM1 CALCOCO2 CALCOCO2 E2F1 E2F1 SRC SRC STK35 STK35 BCL2L1 BCL2L1 USP31 USP31 EIF2AK3 EIF2AK3 FIS1 FIS1 BECN1 BECN1 AGFG2 AGFG2 LOC112400079 LOC112400079 MITF MITF RASL11B RASL11B PRKN PRKN RIT1 RIT1 USP43 USP43 CSNK2A2 CSNK2A2 HIF1A HIF1A TP53 TP53 HRAS HRAS RELA RELA USP11 USP11 SPEN SPEN AMBRA1 AMBRA1 PINK1 PINK1 MFN2 MFN2 MRAS MRAS RAB7B RAB7B RPS27A RPS27A LOC112404921 LOC112404921 ATG9B ATG9B FUNDC2 FUNDC2 MFN1 MFN1 FOXO3 FOXO3 ATG5 ATG5 TAX1BP1 TAX1BP1 JUN JUN RRAS2 RRAS2 USP32 USP32 TFEC TFEC UBC UBC RHOT2 RHOT2 METTL17 METTL17 USP8 USP8 BNIP3 BNIP3 ATG9A ATG9A RAB7A RAB7A MAPK10 MAPK10 SQSTM1 SQSTM1 CSDE1 CSDE1 NRAS NRAS MAPK9 MAPK9 GEM GEM OPTN OPTN PDIK1L PDIK1L TFEB TFEB UBA52 UBA52 BNIP3L BNIP3L NPAS1 NPAS1 RRAS RRAS TFE3 TFE3 ERAS ERAS TBC1D17 TBC1D17 HIF3A HIF3A SP1 SP1 USP15 USP15 TBK1 TBK1 LOC112394096 LOC112394096 RHOT1 RHOT1 GABARAPL2 GABARAPL2 FUNDC1 FUNDC1 LOC112392958 LOC112392958 LOC112392901 LOC112392901 LOC112392093 LOC112392093 RRAD RRAD GABARAPL1 GABARAPL1 KRAS KRAS GABARAP GABARAP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BCL2L13Bcl-2-like protein 13 isoform X1. (449 aa)
TBC1D15TBC1 domain family member 15 isoform X1. (691 aa)
USP4Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (963 aa)
USP19Ubiquitin carboxyl-terminal hydrolase 19. (1361 aa)
TOMM7Mitochondrial import receptor subunit TOM7 homolog. (55 aa)
CITED4Cbp/p300-interacting transactivator 4. (146 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4. (350 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
LY6G5BLymphocyte antigen 6 complex locus protein G5b. (197 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa)
ULK1Serine/threonine-protein kinase ULK1 isoform X1. (972 aa)
LOC112396539LOW QUALITY PROTEIN: GTP-binding protein Rit2-like. (88 aa)
BECN2Beclin-2. (432 aa)
CITED2Cbp/p300-interacting transactivator 2. (263 aa)
PGAM5Serine/threonine-protein phosphatase PGAM5, mitochondrial isoform X1. (282 aa)
USP30Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (517 aa)
AGFG1arf-GAP domain and FG repeat-containing protein 1 isoform X1. (578 aa)
REM2GTP-binding protein REM 2 isoform X1. (388 aa)
NPAS3Neuronal PAS domain-containing protein 3. (953 aa)
NBR1Next to BRCA1 gene 1 protein isoform X1. (895 aa)
CSNK2A1Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (391 aa)
REM1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (300 aa)
CALCOCO2Calcium-binding and coiled-coil domain-containing protein 2. (448 aa)
E2F1Transcription factor E2F1. (360 aa)
SRCTyrosine-protein kinase. (601 aa)
STK35Serine/threonine-protein kinase 35. (539 aa)
BCL2L1Bcl-2-like protein 1 isoform X1. (233 aa)
USP31Ubiquitin carboxyl-terminal hydrolase 31; Belongs to the peptidase C19 family. (1075 aa)
EIF2AK3Eukaryotic translation initiation factor 2-alpha kinase 3 isoform X1. (1128 aa)
FIS1Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa)
BECN1Beclin-1 isoform X1. (471 aa)
AGFG2arf-GAP domain and FG repeat-containing protein 2 isoform X1. (446 aa)
LOC112400079FUN14 domain-containing protein 2. (171 aa)
MITFMicrophthalmia-associated transcription factor isoform X1. (526 aa)
RASL11BRas-like protein family member 11B. (248 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (465 aa)
RIT1GTP-binding protein Rit1. (218 aa)
USP43Ubiquitin carboxyl-terminal hydrolase 43; Belongs to the peptidase C19 family. (1103 aa)
CSNK2A2Casein kinase II subunit alpha. (213 aa)
HIF1AHypoxia-inducible factor 1-alpha. (823 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (387 aa)
HRASGTPase HRas isoform X1. (189 aa)
RELATranscription factor p65. (562 aa)
USP11Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (953 aa)
SPENMsx2-interacting protein. (3237 aa)
AMBRA1Activating molecule in BECN1-regulated autophagy protein 1 isoform X2. (1295 aa)
PINK1Serine/threonine-protein kinase PINK1, mitochondrial isoform X1. (530 aa)
MFN2Mitofusin-2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
MRASRas-related protein M-Ras. (208 aa)
RAB7BRas-related protein Rab-7b isoform X1. (210 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
LOC112404921LOW QUALITY PROTEIN: ras-related protein R-Ras2-like. (204 aa)
ATG9BAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (825 aa)
FUNDC2FUN14 domain-containing protein 2. (189 aa)
MFN1Mitofusin-1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (742 aa)
FOXO3Forkhead box protein O3. (672 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
TAX1BP1Tax1-binding protein 1 isoform X1. (842 aa)
JUNLOW QUALITY PROTEIN: transcription factor AP-1; Belongs to the bZIP family. (284 aa)
RRAS2Ras-related protein R-Ras2. (190 aa)
USP32Ubiquitin carboxyl-terminal hydrolase 32 isoform X1; Belongs to the peptidase C19 family. (1619 aa)
TFECTranscription factor EC isoform X1. (347 aa)
UBCpolyubiquitin-C. (457 aa)
RHOT2Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (644 aa)
METTL17Methyltransferase-like protein 17, mitochondrial. (460 aa)
USP8Ubiquitin carboxyl-terminal hydrolase 8 isoform X1; Belongs to the peptidase C19 family. (1087 aa)
BNIP3BCL2/adenovirus E1B 19 kDa protein-interacting protein 3. (196 aa)
ATG9AAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (839 aa)
RAB7ARas-related protein Rab-7a. (207 aa)
MAPK10Mitogen-activated protein kinase. (464 aa)
SQSTM1Sequestosome-1 isoform X1. (440 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (798 aa)
NRASGTPase NRas. (189 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
GEMGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (317 aa)
OPTNOptineurin isoform X1. (567 aa)
PDIK1LSerine/threonine-protein kinase PDIK1L isoform X1; Belongs to the protein kinase superfamily. (432 aa)
TFEBLOW QUALITY PROTEIN: transcription factor EB. (473 aa)
UBA52ubiquitin-60S ribosomal protein L40. (128 aa)
BNIP3LBCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like isoform X1. (218 aa)
NPAS1Neuronal PAS domain-containing protein 1. (572 aa)
RRASRas-related protein R-Ras. (209 aa)
TFE3Transcription factor E3 isoform X1. (601 aa)
ERASGTPase ERas. (225 aa)
TBC1D17TBC1 domain family member 17. (647 aa)
HIF3AHypoxia-inducible factor 3-alpha isoform X1. (669 aa)
SP1Transcription factor Sp1. (780 aa)
USP15Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (981 aa)
TBK1Serine/threonine-protein kinase TBK1. (729 aa)
LOC112394096Ubiquitin-like. (144 aa)
RHOT1Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (704 aa)
GABARAPL2Gamma-aminobutyric acid receptor-associated protein-like 2 isoform X1. (145 aa)
FUNDC1FUN14 domain-containing protein 1. (155 aa)
LOC112392958ubiquitin-40S ribosomal protein S27a-like. (157 aa)
LOC112392901FUN14 domain-containing protein 1-like. (155 aa)
LOC112392093Ubiquitin carboxyl-terminal hydrolase 31-like. (153 aa)
RRADGTP-binding protein RAD isoform X1. (352 aa)
GABARAPL1Gamma-aminobutyric acid receptor-associated protein-like 1. (117 aa)
KRASGTPase KRas isoform X3. (227 aa)
GABARAPGamma-aminobutyric acid receptor-associated protein. (117 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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