STRINGSTRING
FGFR4 FGFR4 LOC112400438 LOC112400438 PCGF3 PCGF3 HOXB1 HOXB1 FGF2 FGF2 TCF7 TCF7 STAT3 STAT3 PCGF2 PCGF2 MAPK3 MAPK3 FZD6 FZD6 ACVR2A ACVR2A ID1 ID1 PRRX1 PRRX1 APC APC MEIS1 MEIS1 TBX3 TBX3 LOC112397240 LOC112397240 MYC MYC LHX5 LHX5 LOC112397231 LOC112397231 TCF3 TCF3 ISL1 ISL1 APC2 APC2 POU5F1 POU5F1 PCGF5 PCGF5 FZD5 FZD5 ESRRG ESRRG MAPK11 MAPK11 BMPR2 BMPR2 WNT7B WNT7B ESRRB ESRRB ID2 ID2 MYF5 MYF5 WNT10B WNT10B SMAD1 SMAD1 MAPK12 MAPK12 WNT1 WNT1 INHBC INHBC SMARCAD1 SMARCAD1 ACVR1 ACVR1 ACVR1C ACVR1C ZFHX3 ZFHX3 ACVR1B ACVR1B PCGF6 PCGF6 WNT8B WNT8B INHBE INHBE BMPR1B BMPR1B BMP4 BMP4 SKIL SKIL JAK2 JAK2 MAP2K1 MAP2K1 SMAD3 SMAD3 LOC112392116 LOC112392116 LOC112392060 LOC112392060 LOC112392028 LOC112392028 HOXD1 HOXD1 WNT5B WNT5B LOC112391706 LOC112391706 FGFR3 FGFR3 INHBA INHBA SRY SRY LOC112392089 LOC112392089 NFIL3 NFIL3 IGF1R IGF1R KRAS KRAS IGF1 IGF1 MEIS2 MEIS2 BMPR1A BMPR1A MAP2K2 MAP2K2 HESX1 HESX1 FZD9 FZD9 WNT5A WNT5A REST REST POU5F2 POU5F2 HRAS HRAS PIK3CD PIK3CD PIK3CB PIK3CB NEUROG1 NEUROG1 SMAD5 SMAD5 RIF1 RIF1 PIK3R1 PIK3R1 LOC112404952 LOC112404952 OTX1 OTX1 WNT8A WNT8A PAX6 PAX6 LOC112404954 LOC112404954 KLF4 KLF4 AKT3 AKT3 CTNNB1 CTNNB1 ONECUT1 ONECUT1 LIFR LIFR LOC112406365 LOC112406365 ONECUT2 ONECUT2 DUSP9 DUSP9 HOXA1 HOXA1 SMAD9 SMAD9 PIK3CA PIK3CA FGFR2 FGFR2 RAF1 RAF1 ACVR2B ACVR2B SMAD2 SMAD2 SMAD4 SMAD4 WNT11 WNT11 WNT16 WNT16 TBX2 TBX2 LHX1 LHX1 FZD7 FZD7 AKT1 AKT1 WNT2 WNT2 FZD10 FZD10 INHBB INHBB AXIN1 AXIN1 DVL1 DVL1 AXIN2 AXIN2 WNT9B WNT9B FZD2 FZD2 KLF18 KLF18 HAND1 HAND1 ZIC3 ZIC3 WNT3 WNT3 GRB2 GRB2 SETDB1 SETDB1 WNT6 WNT6 WNT10A WNT10A MAPK1 MAPK1 FZD4 FZD4 JARID2 JARID2 WNT7A WNT7A JAK1 JAK1 CSDE1 CSDE1 NRAS NRAS WNT2B WNT2B FGFR1 FGFR1 WNT9A WNT9A WNT3A WNT3A PCGF1 PCGF1 LOC112413704 LOC112413704 MAPK14 MAPK14 MAPK13 MAPK13 KAT6A KAT6A LOC112413803 LOC112413803 FZD1 FZD1 IL6ST IL6ST NODAL NODAL WNT4 WNT4 ID3 ID3 DLX5 DLX5 JAK3 JAK3 PIK3R2 PIK3R2 FZD3 FZD3 DVL3 DVL3 SOX2 SOX2 ISL2 ISL2 LIF LIF ZIC1 ZIC1 GSK3B GSK3B AKT2 AKT2 ERAS ERAS DVL2 DVL2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FGFR4Fibroblast growth factor receptor. (810 aa)
LOC112400438Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
PCGF3Polycomb group RING finger protein 3 isoform X1. (270 aa)
HOXB1Homeobox protein Hox-B1. (298 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (304 aa)
TCF7Transcription factor 7 isoform X1. (303 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
PCGF2Polycomb group RING finger protein 2 isoform X1. (389 aa)
MAPK3Mitogen-activated protein kinase 3. (265 aa)
FZD6Frizzled-6; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
ID1DNA-binding protein inhibitor ID-1. (154 aa)
PRRX1Paired mesoderm homeobox protein 1. (245 aa)
APCAdenomatous polyposis coli protein isoform X1. (2863 aa)
MEIS1Homeobox protein Meis1 isoform X1. (465 aa)
TBX3LOW QUALITY PROTEIN: T-box transcription factor TBX3. (734 aa)
LOC112397240Steroid hormone receptor ERR2-like. (206 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa)
LHX5LIM/homeobox protein Lhx5. (326 aa)
LOC112397231Steroid hormone receptor ERR2-like. (200 aa)
TCF3Transcription factor E2-alpha isoform X1. (645 aa)
ISL1Insulin gene enhancer protein ISL-1. (349 aa)
APC2Adenomatous polyposis coli protein 2. (1995 aa)
POU5F1POU domain protein. (363 aa)
PCGF5Polycomb group RING finger protein 5 isoform X1. (256 aa)
FZD5Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (555 aa)
ESRRGEstrogen-related receptor gamma isoform X1. (458 aa)
MAPK11Mitogen-activated protein kinase. (376 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1012 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (356 aa)
ESRRBSteroid hormone receptor ERR2 isoform X1. (454 aa)
ID2DNA-binding protein inhibitor ID-2. (134 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
MAPK12Mitogen-activated protein kinase. (424 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
INHBCInhibin beta C chain. (352 aa)
SMARCAD1annotation not available (1028 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
ZFHX3Zinc finger homeobox protein 3. (3669 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (453 aa)
PCGF6Polycomb group RING finger protein 6 isoform X3. (404 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (325 aa)
INHBEInhibin beta E chain. (351 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (420 aa)
SKILLOW QUALITY PROTEIN: ski-like protein. (664 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
SMAD3Mothers against decapentaplegic homolog. (376 aa)
LOC112392116LOW QUALITY PROTEIN: polycomb group RING finger protein 5-like. (257 aa)
LOC112392060Fibroblast growth factor receptor 1-like. (98 aa)
LOC112392028RE1-silencing transcription factor-like. (305 aa)
HOXD1Homeobox protein Hox-D1. (326 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa)
LOC112391706Homeobox protein NANOG-like. (225 aa)
FGFR3Fibroblast growth factor receptor. (804 aa)
INHBAInhibin beta A chain. (474 aa)
SRYSex-determining region Y protein; Transcriptional regulator that controls a genetic switch in male development; Belongs to the SRY family. (211 aa)
LOC112392089RAC-alpha serine/threonine-protein kinase. (138 aa)
NFIL3Nuclear factor interleukin-3-regulated protein; Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor (ATF) sites. Represses promoter activity in osteoblasts. Represses transcriptional activity of PER1. Represses transcriptional activity of PER2 via the B-site on the promoter. Activates transcription from the interleukin-3 promoter in T- cells. Competes for the same consensus-binding site with PAR DNA- bi [...] (462 aa)
IGF1RTyrosine-protein kinase receptor. (1368 aa)
KRASGTPase KRas isoform X3. (227 aa)
IGF1Insulin-like growth factor I isoform X1. (208 aa)
MEIS2Homeobox protein Meis2 isoform X1. (477 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2. (303 aa)
HESX1Homeobox expressed in ES cells 1 isoform X1. (185 aa)
FZD9Frizzled-9; Belongs to the G-protein coupled receptor Fz/Smo family. (564 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
RESTRE1-silencing transcription factor isoform X2. (450 aa)
POU5F2POU domain protein. (335 aa)
HRASGTPase HRas isoform X1. (189 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1078 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
NEUROG1Neurogenin-1. (244 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
RIF1Telomere-associated protein RIF1. (2389 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
LOC112404952Left-right determination factor 2-like. (217 aa)
OTX1Homeobox protein OTX1 isoform X1. (355 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
PAX6Paired box protein Pax-6 isoform X1. (493 aa)
LOC112404954Left-right determination factor 2-like. (252 aa)
KLF4Krueppel-like factor 4 isoform X1. (515 aa)
AKT3Non-specific serine/threonine protein kinase. (531 aa)
CTNNB1Catenin beta-1. (781 aa)
ONECUT1One cut domain family member. (465 aa)
LIFRLeukemia inhibitory factor receptor. (1095 aa)
LOC112406365LOW QUALITY PROTEIN: homeobox protein NANOG-like. (294 aa)
ONECUT2One cut domain family member. (367 aa)
DUSP9Dual specificity protein phosphatase 9. (525 aa)
HOXA1Homeobox protein Hox-A1 isoform X1. (331 aa)
SMAD9Mothers against decapentaplegic homolog. (440 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
FGFR2Fibroblast growth factor receptor. (841 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (508 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
SMAD4Mothers against decapentaplegic homolog. (599 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa)
TBX2T-box transcription factor TBX2. (588 aa)
LHX1LIM/homeobox protein Lhx1. (406 aa)
FZD7Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
AKT1RAC-alpha serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (339 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
FZD10Frizzled-10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
INHBBInhibin beta B chain. (345 aa)
AXIN1Axin-1 isoform X1. (866 aa)
DVL1Segment polarity protein dishevelled homolog DVL-1. (706 aa)
AXIN2Axin-2. (720 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (602 aa)
FZD2Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (709 aa)
KLF18LOW QUALITY PROTEIN: Kruppel like factor 18. (492 aa)
HAND1Heart- and neural crest derivatives-expressed protein 1. (218 aa)
ZIC3Zinc finger protein ZIC 3. (455 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (453 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
SETDB1Histone-lysine N-methyltransferase SETDB1 isoform X1. (1296 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
MAPK1Mitogen-activated protein kinase. (343 aa)
FZD4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
JARID2Protein Jumonji isoform X1. (1235 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
JAK1Tyrosine-protein kinase. (1153 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (798 aa)
NRASGTPase NRas. (189 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
FGFR1Fibroblast growth factor receptor. (722 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (428 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
PCGF1Polycomb group RING finger protein 1. (259 aa)
LOC112413704LOW QUALITY PROTEIN: frizzled-8-like; Belongs to the G-protein coupled receptor Fz/Smo family. (420 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
MAPK13Mitogen-activated protein kinase. (366 aa)
KAT6AHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (1975 aa)
LOC112413803Polycomb complex protein BMI-1. (326 aa)
FZD1Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family. (644 aa)
IL6STInterleukin-6 receptor subunit beta. (918 aa)
NODALNodal homolog. (348 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa)
ID3DNA-binding protein inhibitor ID-3. (119 aa)
DLX5Homeobox protein DLX-5. (289 aa)
JAK3Tyrosine-protein kinase. (1104 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa)
FZD3Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (468 aa)
DVL3Segment polarity protein dishevelled homolog DVL-3 isoform X1. (716 aa)
SOX2Transcription factor SOX-2. (327 aa)
ISL2Insulin gene enhancer protein ISL-2. (359 aa)
LIFLeukemia inhibitory factor. (202 aa)
ZIC1Zinc finger protein ZIC 1. (447 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
ERASGTPase ERas. (225 aa)
DVL2Segment polarity protein dishevelled homolog DVL-2 isoform X1. (785 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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