STRINGSTRING
LOC112408488 LOC112408488 LOC112395396 LOC112395396 LOC112395027 LOC112395027 LOC112395023 LOC112395023 SH2D1A SH2D1A PPP3CA PPP3CA IFNG IFNG PPP3R2 PPP3R2 PLCG2 PLCG2 MAP2K1 MAP2K1 TYROBP TYROBP PTPN6 PTPN6 SOS2 SOS2 KLRC1 KLRC1 BID BID KLRD1 KLRD1 KRAS KRAS FASLG FASLG SYK SYK SHC3 SHC3 MAP2K2 MAP2K2 LOC112400438 LOC112400438 ICAM1 ICAM1 RAC1 RAC1 ITGAL ITGAL VAV1 VAV1 SH3BP2 SH3BP2 PRKCB PRKCB MAPK3 MAPK3 FAS FAS LAT LAT LOC112398972 LOC112398972 PLCG1 PLCG1 BRAF BRAF LOC112397808 LOC112397808 CD247 CD247 PRKCG PRKCG CD48 CD48 CSF2 CSF2 PTPN11 PTPN11 SHC2 SHC2 FYN FYN TNFSF10 TNFSF10 PPP3CB PPP3CB LOC112395398 LOC112395398 TNF TNF LOC112395028 LOC112395028 LOC112395029 LOC112395029 LOC112395020 LOC112395020 NCR3 NCR3 LOC112401433 LOC112401433 RAET1E RAET1E LOC112401554 LOC112401554 TNFRSF10A TNFRSF10A PPP3CC PPP3CC SHC1 SHC1 HRAS HRAS LOC112402267 LOC112402267 CEP152 CEP152 SHC4 SHC4 PAK1 PAK1 PIK3CD PIK3CD ARAF ARAF NFATC2 NFATC2 PIK3CB PIK3CB PTK6 PTK6 SH2D1B SH2D1B LOC112403906 LOC112403906 PIK3R1 PIK3R1 LCP2 LCP2 SOS1 SOS1 NCR1 NCR1 NFATC1 NFATC1 PIK3CA PIK3CA LOC112406425 LOC112406425 IFNB1 IFNB1 RAF1 RAF1 LOC112407025 LOC112407025 FCER1G FCER1G LOC112408000 LOC112408000 CD244 CD244 IFNGR2 IFNGR2 IFNAR1 IFNAR1 ITGB2 ITGB2 IFNAR2 IFNAR2 IFNGR1 IFNGR1 CASP3 CASP3 LOC112409948 LOC112409948 RAC3 RAC3 PRKCA PRKCA ICAM2 ICAM2 RAC2 RAC2 GRB2 GRB2 VAV2 VAV2 MAPK1 MAPK1 CSDE1 CSDE1 NRAS NRAS PRF1 PRF1 LCK LCK PTK2B PTK2B PIK3R2 PIK3R2 LOC112415973 LOC112415973 LOC112415970 LOC112415970 ERAS ERAS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC112408488Serine/threonine-protein kinase B-raf-like. (250 aa)
LOC112395396LOW QUALITY PROTEIN: MHC class I polypeptide-related sequence B-like. (327 aa)
LOC112395027Interferon alpha-1-like. (189 aa)
LOC112395023Interferon alpha-1-like. (189 aa)
SH2D1ASH2 domain-containing protein 1A; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2. (128 aa)
PPP3CASerine/threonine-protein phosphatase. (511 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
PPP3R2LOW QUALITY PROTEIN: calcineurin subunit B type 2. (229 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
TYROBPTYRO protein tyrosine kinase-binding protein isoform X1. (126 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)
SOS2Son of sevenless homolog 2 isoform X1. (1272 aa)
KLRC1NKG2-A/NKG2-B type II integral membrane protein isoform X1. (278 aa)
BIDBH3-interacting domain death agonist isoform X1. (326 aa)
KLRD1Natural killer cells antigen CD94 isoform X1. (199 aa)
KRASGTPase KRas isoform X3. (227 aa)
FASLGTumor necrosis factor ligand superfamily member 6; Belongs to the tumor necrosis factor family. (262 aa)
SYKTyrosine-protein kinase. (626 aa)
SHC3SHC-transforming protein 3. (470 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2. (303 aa)
LOC112400438Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
ICAM1Intercellular adhesion molecule 1. (536 aa)
RAC1Ras-related C3 botulinum toxin substrate 1. (148 aa)
ITGALIntegrin alpha-L isoform X1; Belongs to the integrin alpha chain family. (1166 aa)
VAV1Proto-oncogene vav isoform X1. (845 aa)
SH3BP2SH3 domain-binding protein 2 isoform X1. (594 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
MAPK3Mitogen-activated protein kinase 3. (265 aa)
FASTumor necrosis factor receptor superfamily member 6 isoform X1. (334 aa)
LATLinker for activation of T-cells family member 1 isoform X1. (260 aa)
LOC112398972Tyrosine-protein kinase. (612 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1179 aa)
BRAFSerine/threonine-protein kinase B-raf isoform X1. (581 aa)
LOC112397808Guanine nucleotide exchange factor VAV3-like. (757 aa)
CD247T-cell surface glycoprotein CD3 zeta chain. (165 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
CD48CD48 antigen. (237 aa)
CSF2Granulocyte-macrophage colony-stimulating factor. (134 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
SHC2SHC-transforming protein 2. (426 aa)
FYNTyrosine-protein kinase. (537 aa)
TNFSF10Tumor necrosis factor ligand superfamily member. (288 aa)
PPP3CBSerine/threonine-protein phosphatase. (480 aa)
LOC112395398LOW QUALITY PROTEIN: MHC class I polypeptide-related sequence A-like. (365 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
LOC112395028LOW QUALITY PROTEIN: interferon alpha-8-like. (171 aa)
LOC112395029LOW QUALITY PROTEIN: interferon alpha-8-like. (171 aa)
LOC112395020Interferon alpha-1-like. (189 aa)
NCR3Natural cytotoxicity triggering receptor 3. (180 aa)
LOC112401433Tumor necrosis factor receptor superfamily member 10B-like. (456 aa)
RAET1ELOW QUALITY PROTEIN: retinoic acid early transcript 1E. (285 aa)
LOC112401554LOW QUALITY PROTEIN: UL16-binding protein 3-like. (235 aa)
TNFRSF10ATumor necrosis factor receptor superfamily member 10A isoform X1. (452 aa)
PPP3CCSerine/threonine-protein phosphatase. (549 aa)
SHC1SHC-transforming protein 1 isoform X1. (609 aa)
HRASGTPase HRas isoform X1. (189 aa)
LOC112402267Tumor necrosis factor receptor superfamily member 22-like. (321 aa)
CEP152Centrosomal protein of 152 kDa. (1724 aa)
SHC4SHC-transforming protein 4 isoform X1. (630 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1078 aa)
ARAFSerine/threonine-protein kinase A-Raf isoform X1. (625 aa)
NFATC2Nuclear factor of activated T-cells, cytoplasmic 2 isoform X1. (943 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
PTK6LOW QUALITY PROTEIN: protein-tyrosine kinase 6. (367 aa)
SH2D1BSH2 domain-containing protein 1B isoform X1. (136 aa)
LOC112403906Low affinity immunoglobulin gamma Fc region receptor III-like isoform X1. (257 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
LCP2Lymphocyte cytosolic protein 2 isoform X1. (555 aa)
SOS1Son of sevenless homolog 1 isoform X1. (1350 aa)
NCR1Natural cytotoxicity triggering receptor 1 isoform X1. (427 aa)
NFATC1Nuclear factor of activated T-cells, cytoplasmic 1. (700 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC112406425LOW QUALITY PROTEIN: putative killer cell immunoglobulin-like receptor like protein KIR3DP1. (232 aa)
IFNB1Interferon beta. (185 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa)
LOC112407025Interferon alpha-1-like. (189 aa)
FCER1GHigh affinity immunoglobulin epsilon receptor subunit gamma. (86 aa)
LOC112408000Guanine nucleotide exchange factor VAV3. (209 aa)
CD244Natural killer cell receptor 2B4. (369 aa)
IFNGR2Interferon gamma receptor 2 isoform X2. (364 aa)
IFNAR1Interferon alpha/beta receptor 1 isoform X1. (561 aa)
ITGB2Integrin beta. (770 aa)
IFNAR2Interferon alpha/beta receptor 2 isoform X1. (533 aa)
IFNGR1Interferon gamma receptor 1 isoform X1. (468 aa)
CASP3Caspase-3 isoform X1; Belongs to the peptidase C14A family. (307 aa)
LOC112409948Tyrosine-protein phosphatase non-receptor type 11-like isoform X1. (671 aa)
RAC3Ras-related C3 botulinum toxin substrate 3. (221 aa)
PRKCANon-specific serine/threonine protein kinase. (541 aa)
ICAM2Intercellular adhesion molecule 2 isoform X1. (290 aa)
RAC2Ras-related C3 botulinum toxin substrate 2. (197 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
VAV2Guanine nucleotide exchange factor VAV2. (868 aa)
MAPK1Mitogen-activated protein kinase. (343 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (798 aa)
NRASGTPase NRas. (189 aa)
PRF1Perforin-1. (555 aa)
LCKTyrosine-protein kinase. (509 aa)
PTK2BProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa)
LOC112415973Granzyme B-like isoform X1; Belongs to the peptidase S1 family. (248 aa)
LOC112415970LOW QUALITY PROTEIN: mast cell protease 3-like; Belongs to the peptidase S1 family. (282 aa)
ERASGTPase ERas. (225 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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