STRINGSTRING
SYK SYK GAB2 GAB2 PIK3CB PIK3CB FCER1A FCER1A PLA2G4A PLA2G4A PTK6 PTK6 MAP2K3 MAP2K3 IL4 IL4 PIK3R1 PIK3R1 MAP2K4 MAP2K4 LCP2 LCP2 SOS1 SOS1 AKT3 AKT3 ALOX5AP ALOX5AP PIK3CA PIK3CA RAF1 RAF1 FCER1G FCER1G LOC112408000 LOC112408000 AKT1 AKT1 PDPK1 PDPK1 RAC3 RAC3 PRKCA PRKCA MAP2K6 MAP2K6 RAC2 RAC2 GRB2 GRB2 VAV2 VAV2 MAPK1 MAPK1 MAPK10 MAPK10 CSDE1 CSDE1 NRAS NRAS MAPK9 MAPK9 MAPK14 MAPK14 MAPK13 MAPK13 PIK3R2 PIK3R2 AKT2 AKT2 ERAS ERAS IL13 IL13 HRAS HRAS MS4A2 MS4A2 PIK3CD PIK3CD IL5 IL5 BTK BTK MAP2K7 MAP2K7 MAP2K2 MAP2K2 LOC112400438 LOC112400438 RAC1 RAC1 VAV1 VAV1 MAPK3 MAPK3 LAT LAT PLCG1 PLCG1 LYN LYN LOC112397808 LOC112397808 LOC112397463 LOC112397463 CSF2 CSF2 FYN FYN INPP5D INPP5D TNF TNF ALOX5 ALOX5 MAPK8 MAPK8 MAPK11 MAPK11 MAPK12 MAPK12 PLCG2 PLCG2 MAP2K1 MAP2K1 PLA2G4F PLA2G4F PLA2G4E PLA2G4E SOS2 SOS2 LOC112392089 LOC112392089 PLA2G4D PLA2G4D LOC112391147 LOC112391147 KRAS KRAS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SYKTyrosine-protein kinase. (626 aa)
GAB2GRB2-associated-binding protein 2 isoform X1. (670 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
FCER1AHigh affinity immunoglobulin epsilon receptor subunit alpha isoform X1. (258 aa)
PLA2G4APhospholipase A2. (749 aa)
PTK6LOW QUALITY PROTEIN: protein-tyrosine kinase 6. (367 aa)
MAP2K3Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (133 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
MAP2K4Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (362 aa)
LCP2Lymphocyte cytosolic protein 2 isoform X1. (555 aa)
SOS1Son of sevenless homolog 1 isoform X1. (1350 aa)
AKT3Non-specific serine/threonine protein kinase. (531 aa)
ALOX5APArachidonate 5-lipoxygenase-activating protein isoform X1. (204 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa)
FCER1GHigh affinity immunoglobulin epsilon receptor subunit gamma. (86 aa)
LOC112408000Guanine nucleotide exchange factor VAV3. (209 aa)
AKT1RAC-alpha serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (339 aa)
PDPK13-phosphoinositide-dependent protein kinase 1 isoform X1. (531 aa)
RAC3Ras-related C3 botulinum toxin substrate 3. (221 aa)
PRKCANon-specific serine/threonine protein kinase. (541 aa)
MAP2K6Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
RAC2Ras-related C3 botulinum toxin substrate 2. (197 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
VAV2Guanine nucleotide exchange factor VAV2. (868 aa)
MAPK1Mitogen-activated protein kinase. (343 aa)
MAPK10Mitogen-activated protein kinase. (464 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (798 aa)
NRASGTPase NRas. (189 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
MAPK13Mitogen-activated protein kinase. (366 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
ERASGTPase ERas. (225 aa)
IL13Interleukin-13. (145 aa)
HRASGTPase HRas isoform X1. (189 aa)
MS4A2High affinity immunoglobulin epsilon receptor subunit beta. (242 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1078 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (135 aa)
BTKTyrosine-protein kinase. (687 aa)
MAP2K7Dual specificity mitogen-activated protein kinase kinase 7. (399 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2. (303 aa)
LOC112400438Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
RAC1Ras-related C3 botulinum toxin substrate 1. (148 aa)
VAV1Proto-oncogene vav isoform X1. (845 aa)
MAPK3Mitogen-activated protein kinase 3. (265 aa)
LATLinker for activation of T-cells family member 1 isoform X1. (260 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1179 aa)
LYNTyrosine-protein kinase. (518 aa)
LOC112397808Guanine nucleotide exchange factor VAV3-like. (757 aa)
LOC112397463Interleukin-3-like. (149 aa)
CSF2Granulocyte-macrophage colony-stimulating factor. (134 aa)
FYNTyrosine-protein kinase. (537 aa)
INPP5DPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1. (1187 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
ALOX5Arachidonate 5-lipoxygenase isoform X1. (696 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
MAPK11Mitogen-activated protein kinase. (376 aa)
MAPK12Mitogen-activated protein kinase. (424 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
PLA2G4FPhospholipase A2. (849 aa)
PLA2G4EPhospholipase A2. (898 aa)
SOS2Son of sevenless homolog 2 isoform X1. (1272 aa)
LOC112392089RAC-alpha serine/threonine-protein kinase. (138 aa)
PLA2G4DPhospholipase A2. (817 aa)
LOC112391147Phospholipase A2. (1002 aa)
KRASGTPase KRas isoform X3. (227 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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