STRINGSTRING
ARSI ARSI PPP1CB PPP1CB AKT2 AKT2 GSK3B GSK3B PRKACB PRKACB GRIA4 GRIA4 PPP2R2A PPP2R2A GNG8 GNG8 GSK3A GSK3A PPP2R1A PPP2R1A PRKACA PRKACA GNGT1 GNGT1 PPP2R3B PPP2R3B GNG5 GNG5 CACNA1A CACNA1A GNG14 GNG14 GNG11 GNG11 ITPR3 ITPR3 MAPK13 MAPK13 PPP2R5D PPP2R5D MAPK14 MAPK14 DDC DDC PLCB4 PLCB4 MAPK9 MAPK9 PPP2CB PPP2CB GNAL GNAL PLCB1 PLCB1 MAPK10 MAPK10 COMT COMT CACNA1B CACNA1B CREB3 CREB3 ARRB1 ARRB1 PPP2R3C PPP2R3C PPP2R2D PPP2R2D CALY CALY CALML4 CALML4 GNG4 GNG4 SLC18A1 SLC18A1 PRKCA PRKCA LOC112410281 LOC112410281 CALML6 CALML6 GNG13 GNG13 GNB1 GNB1 PVALEF PVALEF GRIN2A GRIN2A GRIA1 GRIA1 PPP2R5C PPP2R5C PPP1CC PPP1CC KCNJ6 KCNJ6 AKT1 AKT1 ARNTL ARNTL LOC112407558 LOC112407558 ADCY5 ADCY5 LOC112407559 LOC112407559 KIF5C KIF5C ARR3 ARR3 SLC18A2 SLC18A2 GNB4 GNB4 CREB5 CREB5 PPP2R1B PPP2R1B GNB5 GNB5 AKT3 AKT3 DRD2 DRD2 DRD1 DRD1 CALM2 CALM2 PPP2R5A PPP2R5A PPP2R5E PPP2R5E GNAO1 GNAO1 KCNJ9 KCNJ9 KIF5B KIF5B LOC112402987 LOC112402987 LOC112402955 LOC112402955 CREB3L1 CREB3L1 TH TH PPP2R5B PPP2R5B PLCB3 PLCB3 DRD4 DRD4 PPP1CA PPP1CA GNG3 GNG3 CREB3L4 CREB3L4 PPP3CC PPP3CC GRIA3 GRIA3 CAMK2B CAMK2B LOC112400993 LOC112400993 ITPR1 ITPR1 CLOCK CLOCK CACNA1D CACNA1D PPP2R3A PPP2R3A GRIA2 GRIA2 GNB2 GNB2 CREB3L3 CREB3L3 CAMK2D CAMK2D PPP2CA PPP2CA PRKCB PRKCB GNGT2 GNGT2 PPP1R1B PPP1R1B PRKCG PRKCG GNAI3 GNAI3 KCNJ5 KCNJ5 DRD5 DRD5 CREB3L2 CREB3L2 GNG7 GNG7 PPP3CB PPP3CB CAMK2G CAMK2G ATF6B ATF6B MAPK8 MAPK8 LOC112395611 LOC112395611 ATF4 ATF4 MAPK11 MAPK11 FOS FOS GNAI1 GNAI1 GNAI2 GNAI2 CREB1 CREB1 MAPK12 MAPK12 CALM1 CALM1 KIF5A KIF5A PPP2R2C PPP2R2C DRD3 DRD3 PPP3CA PPP3CA KCNJ3 KCNJ3 LOC112393584 LOC112393584 ARRB2 ARRB2 MAOA MAOA GRIN2B GRIN2B ITPR2 ITPR2 GNG2 GNG2 GNG12 GNG12 ATF2 ATF2 GNB3 GNB3 MAOB MAOB CACNA1C CACNA1C LOC112392089 LOC112392089 LOC112390773 LOC112390773 CAMK2A CAMK2A GNG10 GNG10 SLC6A3 SLC6A3 PPP2R2B PPP2R2B PLCB2 PLCB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ARSIArylsulfatase I. (573 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
GRIA4Glutamate receptor 4 isoform X2. (902 aa)
PPP2R2ASerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (288 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
GSK3AGlycogen synthase kinase-3 alpha. (320 aa)
PPP2R1ASerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (589 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha. (293 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
PPP2R3BSerine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta. (578 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2284 aa)
GNG14LOW QUALITY PROTEIN: putative guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-14. (101 aa)
GNG11Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 isoform X1. (95 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2670 aa)
MAPK13Mitogen-activated protein kinase. (366 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (602 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
DDCaromatic-L-amino-acid decarboxylase. (514 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
PPP2CBSerine/threonine-protein phosphatase. (244 aa)
GNALGuanine nucleotide-binding protein G(Olf) subunit alpha. (380 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1211 aa)
MAPK10Mitogen-activated protein kinase. (464 aa)
COMTCatechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. (271 aa)
CACNA1BVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (1986 aa)
CREB3Cyclic AMP-responsive element-binding protein 3. (371 aa)
ARRB1Beta-arrestin-1 isoform X1. (418 aa)
PPP2R3CSerine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform X1. (453 aa)
PPP2R2DSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (449 aa)
CALYNeuron-specific vesicular protein calcyon. (234 aa)
CALML4Calmodulin-like protein 4 isoform X1. (150 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
SLC18A1Chromaffin granule amine transporter isoform X1. (523 aa)
PRKCANon-specific serine/threonine protein kinase. (541 aa)
LOC112410281annotation not available (287 aa)
CALML6Calmodulin-like protein 6 isoform X1. (216 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
GNB1Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa)
PVALEFParvalbumin-like EF-hand-containing protein. (134 aa)
GRIN2AGlutamate receptor ionotropic, NMDA 2A isoform X1. (1464 aa)
GRIA1Glutamate receptor 1 isoform X1. (906 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (538 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
KCNJ6G protein-activated inward rectifier potassium channel 2. (514 aa)
AKT1RAC-alpha serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (339 aa)
ARNTLAryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X1. (631 aa)
LOC112407558Calmodulin-like. (140 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1204 aa)
LOC112407559Calmodulin-like protein 3; Belongs to the calmodulin family. (190 aa)
KIF5CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (957 aa)
ARR3arrestin-C. (393 aa)
SLC18A2Synaptic vesicular amine transporter isoform X1. (517 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4 isoform X1. (340 aa)
CREB5Cyclic AMP-responsive element-binding protein 5. (502 aa)
PPP2R1BSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X2. (696 aa)
GNB5Guanine nucleotide-binding protein subunit beta-5 isoform X3. (414 aa)
AKT3Non-specific serine/threonine protein kinase. (531 aa)
DRD2D(2) dopamine receptor isoform X2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
DRD1D(1A) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (452 aa)
CALM2Calmodulin-2; Belongs to the calmodulin family. (149 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (488 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (467 aa)
GNAO1LOW QUALITY PROTEIN: guanine nucleotide-binding protein G(O) subunit alpha. (363 aa)
KCNJ9G protein-activated inward rectifier potassium channel 3. (393 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (998 aa)
LOC112402987Neuroendocrine secretory protein 55-like. (241 aa)
LOC112402955Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas-like. (946 aa)
CREB3L1Cyclic AMP-responsive element-binding protein 3-like protein 1. (520 aa)
THTyrosine 3-monooxygenase. (462 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (497 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1172 aa)
DRD4D(4) dopamine receptor. (205 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
CREB3L4Cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X1. (443 aa)
PPP3CCSerine/threonine-protein phosphatase. (549 aa)
GRIA3Glutamate receptor 3. (888 aa)
CAMK2BCalcium/calmodulin-dependent protein kinase type II subunit beta. (808 aa)
LOC112400993Calmodulin-like; Belongs to the calmodulin family. (149 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2709 aa)
CLOCKCircadian locomoter output cycles protein kaput. (848 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2183 aa)
PPP2R3ASerine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha isoform X1. (1149 aa)
GRIA2Glutamate receptor 2 isoform X1. (940 aa)
GNB2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (340 aa)
CREB3L3Cyclic AMP-responsive element-binding protein 3-like protein 3. (457 aa)
CAMK2DCalcium/calmodulin-dependent protein kinase type II subunit delta; Belongs to the protein kinase superfamily. (449 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
PPP1R1BProtein phosphatase 1 regulatory subunit 1B isoform X1. (177 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
KCNJ5G protein-activated inward rectifier potassium channel 4. (419 aa)
DRD5LOW QUALITY PROTEIN: D(1B) dopamine receptor. (474 aa)
CREB3L2Cyclic AMP-responsive element-binding protein 3-like protein 2. (520 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
PPP3CBSerine/threonine-protein phosphatase. (480 aa)
CAMK2GCalcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1. (507 aa)
ATF6BCyclic AMP-dependent transcription factor ATF-6 beta. (702 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
LOC112395611Guanine nucleotide-binding protein G(Q) subunit alpha. (301 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4. (350 aa)
MAPK11Mitogen-activated protein kinase. (376 aa)
FOSProto-oncogene c-Fos. (380 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
MAPK12Mitogen-activated protein kinase. (424 aa)
CALM1Calmodulin-1; Belongs to the calmodulin family. (149 aa)
KIF5AKinesin heavy chain; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1032 aa)
PPP2R2CSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (447 aa)
DRD3D(3) dopamine receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (400 aa)
PPP3CASerine/threonine-protein phosphatase. (511 aa)
KCNJ3G protein-activated inward rectifier potassium channel 1. (501 aa)
LOC112393584Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2009 aa)
ARRB2Beta-arrestin-2. (409 aa)
MAOAAmine oxidase. (527 aa)
GRIN2BGlutamate receptor ionotropic, NMDA 2B. (1481 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2 isoform X1. (2701 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (86 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform X1. (340 aa)
MAOBAmine oxidase. (520 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2111 aa)
LOC112392089RAC-alpha serine/threonine-protein kinase. (138 aa)
LOC112390773LOW QUALITY PROTEIN: transmembrane O-methyltransferase homolog. (410 aa)
CAMK2ACalcium/calmodulin-dependent protein kinase type II subunit alpha; Belongs to the protein kinase superfamily. (478 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (90 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (617 aa)
PPP2R2BSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (443 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1185 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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