STRINGSTRING
PHKA2 PHKA2 CAMK2G CAMK2G PPP3CB PPP3CB PHKB PHKB ACACB ACACB CREB3L2 CREB3L2 PPP4C PPP4C PHKG1 PHKG1 PHKG2 PHKG2 ARSI ARSI AKT2 AKT2 PRMT1 PRMT1 PRKACB PRKACB GYS1 GYS1 CPT1C CPT1C PRKACA PRKACA PFKFB1 PFKFB1 SIRT1 SIRT1 ITPR3 ITPR3 PLCB4 PLCB4 LOC112412913 LOC112412913 PRKAB2 PRKAB2 LOC112412867 LOC112412867 PLCB1 PLCB1 PRKAG3 PRKAG3 CREB3 CREB3 LDHAL6B LDHAL6B PARP6 PARP6 PKM PKM CALML4 CALML4 GCGR GCGR CALML6 CALML6 PVALEF PVALEF G6PC3 G6PC3 CREBBP CREBBP PRKAB1 PRKAB1 SIK1 SIK1 PFKL PFKL AKT1 AKT1 ACACA ACACA LOC112407559 LOC112407559 PDE3B PDE3B G6PC2 G6PC2 PRKAA2 PRKAA2 FOXO1 FOXO1 CREB5 CREB5 PFKP PFKP PRKAA1 PRKAA1 PRKAG2 PRKAG2 AKT3 AKT3 FBP1 FBP1 SIK2 SIK2 FBP2 FBP2 PCK2 PCK2 CALM2 CALM2 ADCY2 ADCY2 PPP4R3B PPP4R3B PYGB PYGB LOC112403822 LOC112403822 PCK1 PCK1 LOC112402987 LOC112402987 LOC112402955 LOC112402955 CREB3L1 CREB3L1 PLCB3 PLCB3 PYGM PYGM CPT1A CPT1A LOC112401637 LOC112401637 CREB3L4 CREB3L4 PPP3CC PPP3CC GCK GCK CRTC2 CRTC2 CAMK2B CAMK2B LOC112400993 LOC112400993 ITPR1 ITPR1 PGAM2 PGAM2 PDHB PDHB G6PC G6PC PPARGC1A PPARGC1A SLC2A1 SLC2A1 CREB3L3 CREB3L3 CAMK2D CAMK2D PLCB2 PLCB2 CAMK2A CAMK2A PHKA1 PHKA1 GYS2 GYS2 LOC112392089 LOC112392089 TNIK TNIK LOC112407558 LOC112407558 LDHB LDHB ATF2 ATF2 ITPR2 ITPR2 PYGL PYGL SLC2A2 SLC2A2 PGAM1 PGAM1 PPP3R2 PPP3R2 PPP3CA PPP3CA GCG GCG PDHA2 PDHA2 CALM1 CALM1 FAP FAP CPT1B CPT1B PRKAG1 PRKAG1 PPP4R3A PPP4R3A PFKM PFKM PPARA PPARA CREB1 CREB1 EP300 EP300 ATF4 ATF4 PDHA1 PDHA1 LOC112395611 LOC112395611 PARP8 PARP8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PHKA2Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1217 aa)
CAMK2GCalcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1. (507 aa)
PPP3CBSerine/threonine-protein phosphatase. (480 aa)
PHKBPhosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family. (1090 aa)
ACACBacetyl-CoA carboxylase 2. (2456 aa)
CREB3L2Cyclic AMP-responsive element-binding protein 3-like protein 2. (520 aa)
PPP4CSerine/threonine-protein phosphatase. (307 aa)
PHKG1Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform; Belongs to the protein kinase superfamily. (387 aa)
PHKG2Phosphorylase b kinase gamma catalytic chain, liver/testis isoform; Belongs to the protein kinase superfamily. (406 aa)
ARSIArylsulfatase I. (573 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PRMT1Protein arginine N-methyltransferase 1 isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (371 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
GYS1Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (737 aa)
CPT1CCarnitine O-palmitoyltransferase 1, brain isoform isoform X1; Belongs to the carnitine/choline acetyltransferase family. (801 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha. (293 aa)
PFKFB16-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 1 isoform X1. (471 aa)
SIRT1NAD-dependent protein deacetylase sirtuin-1 isoform X1. (557 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2670 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
LOC112412913L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (332 aa)
PRKAB25'-AMP-activated protein kinase subunit beta-2. (272 aa)
LOC112412867LOW QUALITY PROTEIN: L-lactate dehydrogenase C chain-like; Belongs to the LDH/MDH superfamily. (224 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1211 aa)
PRKAG35'-AMP-activated protein kinase subunit gamma-3. (464 aa)
CREB3Cyclic AMP-responsive element-binding protein 3. (371 aa)
LDHAL6BLOW QUALITY PROTEIN: L-lactate dehydrogenase A-like 6B; Belongs to the LDH/MDH superfamily. (335 aa)
PARP6Poly [ADP-ribose] polymerase. (631 aa)
PKMPyruvate kinase; Belongs to the pyruvate kinase family. (531 aa)
CALML4Calmodulin-like protein 4 isoform X1. (150 aa)
GCGRGlucagon receptor; Belongs to the G-protein coupled receptor 2 family. (479 aa)
CALML6Calmodulin-like protein 6 isoform X1. (216 aa)
PVALEFParvalbumin-like EF-hand-containing protein. (134 aa)
G6PC3Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (346 aa)
CREBBPCREB-binding protein. (2443 aa)
PRKAB15'-AMP-activated protein kinase subunit beta-1. (270 aa)
SIK1Serine/threonine-protein kinase SIK1. (657 aa)
PFKLATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (732 aa)
AKT1RAC-alpha serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (339 aa)
ACACAacetyl-CoA carboxylase 1 isoform X2. (2346 aa)
LOC112407559Calmodulin-like protein 3; Belongs to the calmodulin family. (190 aa)
PDE3BPhosphodiesterase. (1119 aa)
G6PC2Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (355 aa)
PRKAA2Non-specific serine/threonine protein kinase. (462 aa)
FOXO1Forkhead box protein O1. (511 aa)
CREB5Cyclic AMP-responsive element-binding protein 5. (502 aa)
PFKPATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (791 aa)
PRKAA1Non-specific serine/threonine protein kinase. (559 aa)
PRKAG25'-AMP-activated protein kinase subunit gamma-2 isoform X1. (566 aa)
AKT3Non-specific serine/threonine protein kinase. (531 aa)
FBP1Fructose-1,6-bisphosphatase 1; Belongs to the FBPase class 1 family. (338 aa)
SIK2Serine/threonine-protein kinase SIK2 isoform X1. (906 aa)
FBP2Fructose-1,6-bisphosphatase isozyme 2; Belongs to the FBPase class 1 family. (339 aa)
PCK2Phosphoenolpyruvate carboxykinase [GTP], mitochondrial isoform X1. (650 aa)
CALM2Calmodulin-2; Belongs to the calmodulin family. (149 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1037 aa)
PPP4R3BSerine/threonine-protein phosphatase 4 regulatory subunit 3B isoform X1. (820 aa)
PYGBAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (843 aa)
LOC112403822Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family. (206 aa)
PCK1Phosphoenolpyruvate carboxykinase, cytosolic [GTP]. (622 aa)
LOC112402987Neuroendocrine secretory protein 55-like. (241 aa)
LOC112402955Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas-like. (946 aa)
CREB3L1Cyclic AMP-responsive element-binding protein 3-like protein 1. (520 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1172 aa)
PYGMAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (842 aa)
CPT1ACarnitine O-palmitoyltransferase 1, liver isoform isoform X1. (823 aa)
LOC112401637L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (374 aa)
CREB3L4Cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X1. (443 aa)
PPP3CCSerine/threonine-protein phosphatase. (549 aa)
GCKPhosphotransferase. (537 aa)
CRTC2CREB-regulated transcription coactivator 2 isoform X1. (701 aa)
CAMK2BCalcium/calmodulin-dependent protein kinase type II subunit beta. (808 aa)
LOC112400993Calmodulin-like; Belongs to the calmodulin family. (149 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2709 aa)
PGAM2Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (253 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (359 aa)
G6PCGlucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa)
PPARGC1APeroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X1. (799 aa)
SLC2A1Solute carrier family 2, facilitated glucose transporter member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (492 aa)
CREB3L3Cyclic AMP-responsive element-binding protein 3-like protein 3. (457 aa)
CAMK2DCalcium/calmodulin-dependent protein kinase type II subunit delta; Belongs to the protein kinase superfamily. (449 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1185 aa)
CAMK2ACalcium/calmodulin-dependent protein kinase type II subunit alpha; Belongs to the protein kinase superfamily. (478 aa)
PHKA1Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1017 aa)
GYS2Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (702 aa)
LOC112392089RAC-alpha serine/threonine-protein kinase. (138 aa)
TNIKTRAF2 and NCK-interacting protein kinase isoform X1. (1331 aa)
LOC112407558Calmodulin-like. (140 aa)
LDHBL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (334 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2 isoform X1. (2701 aa)
PYGLAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (851 aa)
SLC2A2Solute carrier family 2, facilitated glucose transporter member 2 isoform X1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (524 aa)
PGAM1Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (254 aa)
PPP3R2LOW QUALITY PROTEIN: calcineurin subunit B type 2. (229 aa)
PPP3CASerine/threonine-protein phosphatase. (511 aa)
GCGGlucagon isoform X1. (180 aa)
PDHA2annotation not available (387 aa)
CALM1Calmodulin-1; Belongs to the calmodulin family. (149 aa)
FAPProlyl endopeptidase FAP; Belongs to the peptidase S9B family. (760 aa)
CPT1BCarnitine O-palmitoyltransferase 1, muscle isoform. (789 aa)
PRKAG15'-AMP-activated protein kinase subunit gamma-1 isoform X1. (333 aa)
PPP4R3ASerine/threonine-protein phosphatase 4 regulatory subunit 3A isoform X1. (833 aa)
PFKMATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (851 aa)
PPARAPeroxisome proliferator-activated receptor alpha. (468 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
EP300Histone acetyltransferase p300. (2399 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4. (350 aa)
PDHA1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (390 aa)
LOC112395611Guanine nucleotide-binding protein G(Q) subunit alpha. (301 aa)
PARP8Poly [ADP-ribose] polymerase. (929 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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