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| | LOC112412208 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (317 aa) |
| | LOC112412210 | Tubulin alpha-3 chain-like; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (297 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (343 aa) |
| | LOC112412198 | Tubulin alpha-3 chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (313 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (464 aa) |
| | TUBB6 | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (374 aa) |
| | PRNP | Major prion protein; Belongs to the prion family. (261 aa) |
| | PRKACB | cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa) |
| | SLC25A6 | ADP/ATP translocase 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) |
| | PRKACA | cAMP-dependent protein kinase catalytic subunit alpha. (293 aa) |
| | KLC3 | Kinesin light chain 3. (505 aa) |
| | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa) |
| | GRIN2D | Glutamate receptor ionotropic, NMDA 2D; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (940 aa) |
| | NDUFA4 | Cytochrome c oxidase subunit NDUFA4. (82 aa) |
| | NDUFA13 | LOW QUALITY PROTEIN: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13. (164 aa) |
| | LOC112415117 | Cytochrome b-c1 complex subunit 9. (64 aa) |
| | C1QA | Complement C1q subcomponent subunit A. (245 aa) |
| | YJEFN3 | yjeF N-terminal domain-containing protein 3. (249 aa) |
| | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa) |
| | NDUFB7 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7. (134 aa) |
| | LOC112414505 | 26S proteasome complex subunit SEM1 isoform X1. (76 aa) |
| | C1QB | Complement C1q subcomponent subunit B. (290 aa) |
| | C1QC | Complement C1q subcomponent subunit C. (245 aa) |
| | LOC112414233 | Cytochrome b-245 heavy chain isoform X1. (570 aa) |
| | XK | XK-related protein. (444 aa) |
| | LOC112414113 | LOW QUALITY PROTEIN: cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2670 aa) |
| | LOC112413993 | Cytochrome c oxidase subunit 6C-like. (80 aa) |
| | KLC4 | Kinesin light chain 4. (616 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (366 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | VDAC3 | Voltage-dependent anion-selective channel protein 3. (283 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | APAF1 | Apoptotic protease-activating factor 1 isoform X1. (1301 aa) |
| | PSMD9 | 26S proteasome non-ATPase regulatory subunit 9 isoform X1. (223 aa) |
| | CAV1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa) |
| | ATP5PO | ATP synthase subunit O, mitochondrial. (213 aa) |
| | CCL5 | C-C motif chemokine. (91 aa) |
| | NDUFV3 | NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial isoform X1. (477 aa) |
| | SOD1 | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (153 aa) |
| | KLC1 | Kinesin light chain 1 isoform X1. (681 aa) |
| | PSMA8 | Proteasome subunit alpha type. (265 aa) |
| | CAV2 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa) |
| | NDUFA5 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 isoform X1. (118 aa) |
| | SDHC | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial isoform X1. (169 aa) |
| | KIAA1958 | Uncharacterized protein KIAA1958 homolog isoform X3. (744 aa) |
| | LOC112407331 | Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. (111 aa) |
| | NDUFB3 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3. (98 aa) |
| | NDUFS2 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial; Belongs to the complex I 49 kDa subunit family. (463 aa) |
| | KIF5C | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (957 aa) |
| | PSMA1 | Proteasome subunit alpha type. (263 aa) |
| | C8A | Complement component C8 alpha chain. (589 aa) |
| | TUBAL3 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (472 aa) |
| | LOC112407246 | LOW QUALITY PROTEIN: protein phosphatase 1 regulatory subunit 14B-like. (156 aa) |
| | LOC112407288 | Cytochrome c oxidase subunit 6C. (75 aa) |
| | LOC112407344 | Heat shock cognate 71 kDa protein-like. (299 aa) |
| | LOC112406732 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1. (58 aa) |
| | C8B | Complement component C8 beta chain isoform X1. (590 aa) |
| | LOC112406956 | LOW QUALITY PROTEIN: voltage-dependent anion-selective channel protein 2-like. (296 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | FAM71E2 | LOW QUALITY PROTEIN: protein FAM71E2. (815 aa) |
| | NDUFA12 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (145 aa) |
| | NCAM1 | Neural cell adhesion molecule 1. (1145 aa) |
| | NDUFB5 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial isoform X1. (189 aa) |
| | SDHD | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (159 aa) |
| | LOC112406320 | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | C7 | Complement component C7. (779 aa) |
| | CREB5 | Cyclic AMP-responsive element-binding protein 5. (502 aa) |
| | NDUFB6 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 isoform X1. (128 aa) |
| | C9 | Complement component C9 isoform X1. (548 aa) |
| | PSMA4 | Proteasome subunit alpha type. (261 aa) |
| | LOC112405272 | Cytochrome c oxidase subunit 7A-related protein, mitochondrial. (114 aa) |
| | LOC112404949 | Calcium uniporter protein, mitochondrial. (109 aa) |
| | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (531 aa) |
| | NDUFA2 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (99 aa) |
| | HSPA6 | LOW QUALITY PROTEIN: heat shock 70 kDa protein 6; Belongs to the heat shock protein 70 family. (645 aa) |
| | AKAP10 | A-kinase anchor protein 10, mitochondrial isoform X1. (654 aa) |
| | LOC112404308 | LOW QUALITY PROTEIN: NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial-like. (258 aa) |
| | LOC112403809 | Cytochrome b-c1 complex subunit 1, mitochondrial isoform X1. (481 aa) |
| | SLC25A5 | ADP/ATP translocase 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) |
| | NDUFA1 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1. (70 aa) |
| | HSPA2 | Heat shock-related 70 kDa protein 2; Belongs to the heat shock protein 70 family. (638 aa) |
| | LOC112403640 | LOW QUALITY PROTEIN: cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (106 aa) |
| | PTK6 | LOW QUALITY PROTEIN: protein-tyrosine kinase 6. (367 aa) |
| | ATP5F1E | ATP synthase subunit epsilon, mitochondrial. (51 aa) |
| | ADRM1 | Proteasomal ubiquitin receptor ADRM1. (407 aa) |
| | TUBB1 | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (485 aa) |
| | KIF5B | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (998 aa) |
| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa) |
| | PSMA7 | Proteasome subunit alpha type. (248 aa) |
| | LOC112402670 | NADH dehydrogenase [ubiquinone] 1 subunit C2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (120 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1078 aa) |
| | STIP1 | Stress-induced-phosphoprotein 1. (543 aa) |
| | PSMC3 | 26S proteasome regulatory subunit 6A; Belongs to the AAA ATPase family. (423 aa) |
| | OSBPL2 | Oxysterol-binding protein; Belongs to the OSBP family. (534 aa) |
| | BAD | Bcl2-associated agonist of cell death. (168 aa) |
| | CACNA1S | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1866 aa) |
| | CREB3L1 | Cyclic AMP-responsive element-binding protein 3-like protein 1. (520 aa) |
| | CASP9 | Caspase-9; Belongs to the peptidase C14A family. (442 aa) |
| | NDUFV1 | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (472 aa) |
| | PSMD13 | 26S proteasome non-ATPase regulatory subunit 13. (376 aa) |
| | KLC2 | Kinesin light chain 2 isoform X1. (656 aa) |
| | SDHB | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (280 aa) |
| | NDUFB11 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial. (154 aa) |
| | LOC112402273 | Cytochrome c oxidase subunit 8A, mitochondrial. (69 aa) |
| | NDUFS8 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial. (210 aa) |
| | NDUFS3 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial; Belongs to the complex I 30 kDa subunit family. (268 aa) |
| | CREB3L4 | Cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X1. (443 aa) |
| | PPP3CC | Serine/threonine-protein phosphatase. (549 aa) |
| | CSNK2A2 | Casein kinase II subunit alpha. (213 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2709 aa) |
| | NCF1 | Neutrophil cytosol factor 1 isoform X1. (393 aa) |
| | LOC112401388 | Cytochrome b-c1 complex subunit 8. (82 aa) |
| | PSMD6 | 26S proteasome non-ATPase regulatory subunit 6 isoform X1. (389 aa) |
| | EIF2S1 | Eukaryotic translation initiation factor 2 subunit 1. (315 aa) |
| | LOC112401142 | Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (274 aa) |
| | LOC112400398 | Cytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family. (95 aa) |
| | PSMB3 | Proteasome subunit beta. (205 aa) |
| | TUBB4A | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa) |
| | CACNA1D | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2183 aa) |
| | NDUFA11 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11. (141 aa) |
| | PRKCD | Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (675 aa) |
| | PSMD3 | 26S proteasome non-ATPase regulatory subunit 3. (534 aa) |
| | LOC112400438 | Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa) |
| | LOC112400382 | Cytochrome c oxidase subunit 7B, mitochondrial. (80 aa) |
| | RAC1 | Ras-related C3 botulinum toxin substrate 1. (148 aa) |
| | CACNA1F | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1910 aa) |
| | CREB3L3 | Cyclic AMP-responsive element-binding protein 3-like protein 3. (457 aa) |
| | NDUFA7 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7. (113 aa) |
| | SOD3 | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (244 aa) |
| | LOC112399364 | Cytochrome b-c1 complex subunit 2, mitochondrial; Belongs to the peptidase M16 family. (453 aa) |
| | LOC112399312 | Cytochrome c oxidase subunit 6A, mitochondrial. (97 aa) |
| | PSMB1 | Proteasome subunit beta. (314 aa) |
| | NDUFAB1 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (156 aa) |
| | NDUFC1 | NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial. (76 aa) |
| | MAPK3 | Mitogen-activated protein kinase 3. (265 aa) |
| | SLC25A31 | LOW QUALITY PROTEIN: ADP/ATP translocase 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (324 aa) |
| | VDAC1 | Voltage-dependent anion-selective channel protein 1. (283 aa) |
| | LOC112398970 | Cytochrome c oxidase subunit 5B, mitochondrial. (111 aa) |
| | EIF2AK3 | Eukaryotic translation initiation factor 2-alpha kinase 3 isoform X1. (1128 aa) |
| | LOC112398864 | Cytochrome c oxidase subunit 6C-like. (65 aa) |
| | ATP5MC1 | ATP synthase F(0) complex subunit C1, mitochondrial; Belongs to the ATPase C chain family. (136 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (266 aa) |
| | IL1A | Interleukin-1; Belongs to the IL-1 family. (265 aa) |
| | NDUFA3 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 isoform X1. (140 aa) |
| | LOC112398719 | Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. (111 aa) |
| | PSMA5 | Proteasome subunit alpha type. (241 aa) |
| | NDUFB2 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial. (105 aa) |
| | CSNK2A1 | Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (391 aa) |
| | PSMB5 | Proteasome subunit beta. (263 aa) |
| | LOC112397996 | Cytochrome c oxidase subunit NDUFA4-like. (90 aa) |
| | LOC112397075 | Cytochrome c1, heme protein, mitochondrial. (326 aa) |
| | NDUFB9 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 isoform X1; Belongs to the complex I LYR family. (193 aa) |
| | CREB3L2 | Cyclic AMP-responsive element-binding protein 3-like protein 2. (520 aa) |
| | C6 | Complement component C6. (794 aa) |
| | PPIF | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (205 aa) |
| | LOC112397274 | Cytochrome c oxidase subunit 6A, mitochondrial. (108 aa) |
| | SAMD8 | Sphingomyelin synthase-related protein 1 isoform X1. (615 aa) |
| | LOC112396394 | Cytochrome b-c1 complex subunit 10. (56 aa) |
| | GRIN3B | LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 3B; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (939 aa) |
| | LOC112396164 | Calcium uniporter protein, mitochondrial-like. (89 aa) |
| | FYN | Tyrosine-protein kinase. (537 aa) |
| | PPP3CB | Serine/threonine-protein phosphatase. (480 aa) |
| | LOC112396438 | Cytochrome c-like. (69 aa) |
| | HSPA8 | Heat shock cognate 71 kDa protein; Belongs to the heat shock protein 70 family. (650 aa) |
| | CAV3 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa) |
| | NDUFS4 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial. (175 aa) |
| | NDUFS7 | LOW QUALITY PROTEIN: NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial. (194 aa) |
| | ATP5F1D | ATP synthase subunit delta, mitochondrial. (378 aa) |
| | PSMB2 | Proteasome subunit beta. (201 aa) |
| | NDUFS5 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 5. (104 aa) |
| | TUBB | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa) |
| | CSNK2B | Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa) |
| | LOC112396093 | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (153 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | LOC112395264 | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa) |
| | LY6G5B | Lymphocyte antigen 6 complex locus protein G5b. (197 aa) |
| | ATF6B | Cyclic AMP-dependent transcription factor ATF-6 beta. (702 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | IL6 | Interleukin-6. (208 aa) |
| | NDUFS1 | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial; Belongs to the complex I 75 kDa subunit family. (727 aa) |
| | ATF4 | Cyclic AMP-dependent transcription factor ATF-4. (350 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (376 aa) |
| | LOC112395513 | Uncharacterized protein LOC112395513. (227 aa) |
| | LOC112395427 | Heat shock 70 kDa protein 1-like; Belongs to the heat shock protein 70 family. (641 aa) |
| | NDUFA6 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (127 aa) |
| | DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa) |
| | LOC112394329 | Proteasome subunit alpha type. (255 aa) |
| | CREB1 | Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa) |
| | LOC112395175 | Tubulin alpha-1C chain-like; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (179 aa) |
| | PSMC2 | 26S proteasome regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa) |
| | LOC112394363 | Cytochrome c oxidase subunit 6C-like. (75 aa) |
| | ATP5PB | ATP synthase F(0) complex subunit B1, mitochondrial. (256 aa) |
| | NDUFB4 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4. (129 aa) |
| | LOC112415739 | LOW QUALITY PROTEIN: caspase-12-like; Belongs to the peptidase C14A family. (337 aa) |
| | BAX | Apoptosis regulator BAX. (192 aa) |
| | COX2 | Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. (227 aa) |
| | GSK3B | Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa) |
| | PSMC4 | 26S proteasome regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa) |
| | NDUFA4L2 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2. (87 aa) |
| | ATP5MC2 | ATP synthase F(0) complex subunit C2, mitochondrial; Belongs to the ATPase C chain family. (142 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (424 aa) |
| | PSMD11 | 26S proteasome non-ATPase regulatory subunit 11. (422 aa) |
| | ATP5F1B | ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (528 aa) |
| | KIF5A | Kinesin heavy chain; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1032 aa) |
| | NDUFB1 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1. (185 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (511 aa) |
| | LOC112394162 | Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa) |
| | LOC112394116 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa) |
| | LOC112394117 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa) |
| | LOC112393500 | Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (192 aa) |
| | PSMC1 | 26S proteasome regulatory subunit 4; Belongs to the AAA ATPase family. (440 aa) |
| | PSMD14 | 26S proteasome non-ATPase regulatory subunit 14 isoform X1. (310 aa) |
| | PPP3R2 | LOW QUALITY PROTEIN: calcineurin subunit B type 2. (229 aa) |
| | PSMB6 | Proteasome subunit beta. (255 aa) |
| | LOC112393437 | Cytochrome c oxidase subunit 4 isoform 1, mitochondrial. (169 aa) |
| | PSMC6 | 26S proteasome regulatory subunit 10B; Belongs to the AAA ATPase family. (403 aa) |
| | LOC112393335 | Uncharacterized protein LOC112393335; Belongs to the tubulin family. (916 aa) |
| | GRIN3A | Glutamate receptor ionotropic, NMDA 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1115 aa) |
| | LOC112392581 | Cytochrome c oxidase subunit 7C, mitochondrial. (63 aa) |
| | LOC112392016 | Heat shock 70 kDa protein 1B. (174 aa) |
| | LOC112392009 | Heat shock 70 kDa protein. (156 aa) |
| | NDUFB8 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (186 aa) |
| | GRIN2B | Glutamate receptor ionotropic, NMDA 2B. (1481 aa) |
| | ATP5F1A | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (553 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2 isoform X1. (2701 aa) |
| | LOC112392004 | Heat shock 70 kDa protein 1B-like. (124 aa) |
| | LOC112391536 | Cytochrome c 2; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa) |
| | NDUFA9 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial. (377 aa) |
| | RYR1 | Ryanodine receptor 1. (4879 aa) |
| | LOC112392309 | Cytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B. (86 aa) |
| | PSMA2 | Proteasome subunit alpha type. (234 aa) |
| | ATP5MC3 | ATP synthase F(0) complex subunit C3, mitochondrial; Belongs to the ATPase C chain family. (141 aa) |
| | LOC112392299 | Cytochrome c oxidase subunit 7A1, mitochondrial. (154 aa) |
| | TUBA8 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (496 aa) |
| | PSMD8 | 26S proteasome non-ATPase regulatory subunit 8. (351 aa) |
| | CACNA1C | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2111 aa) |
| | LAMC1 | Laminin subunit gamma-1. (1608 aa) |
| | NCF2 | Neutrophil cytosol factor 2 isoform X1. (526 aa) |
| | MRPL39 | 39S ribosomal protein L39, mitochondrial isoform X1. (364 aa) |
| | LOC112390829 | Cytochrome c oxidase subunit 7A2, mitochondrial. (83 aa) |
| | RYR3 | Ryanodine receptor 3. (4869 aa) |
| | ATP5F1C | ATP synthase subunit gamma. (298 aa) |
| | PSMA3 | Proteasome subunit alpha type. (255 aa) |
| | LOC112391027 | LOW QUALITY PROTEIN: voltage-dependent anion-selective channel protein 3-like. (336 aa) |
| | ATP5PF | ATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family. (108 aa) |
| | NCAM2 | Neural cell adhesion molecule 2. (842 aa) |
| | NDUFS6 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (124 aa) |
| | SDHA | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (665 aa) |
| | LOC112390687 | Cytochrome c oxidase subunit 7B2, mitochondrial-like. (81 aa) |
| | CYTB | Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (379 aa) |
| | ND5 | NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (606 aa) |
| | ATP8 | ATP synthase protein 8; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (63 aa) |
| | ND1 | NADH-ubiquinone oxidoreductase chain 1; Belongs to the complex I subunit 1 family. (318 aa) |
| | ATP6 | ATP synthase subunit a. (226 aa) |
| | ND6 | NADH-ubiquinone oxidoreductase chain 6; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (175 aa) |
| | ND4L | NADH-ubiquinone oxidoreductase chain 4L; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (98 aa) |
| | ND3 | NADH-ubiquinone oxidoreductase chain 3; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (115 aa) |
| | NDUFB10 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 isoform X1. (202 aa) |
| | LOC112409526 | Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | NDUFA10 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (355 aa) |
| | SLC25A4 | ADP/ATP translocase 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) |
| | CASP3 | Caspase-3 isoform X1; Belongs to the peptidase C14A family. (307 aa) |
| | GRIN2A | Glutamate receptor ionotropic, NMDA 2A isoform X1. (1464 aa) |
| | GRIN2C | Glutamate receptor ionotropic, NMDA 2C. (1137 aa) |
| | PSMC5 | 26S proteasome regulatory subunit 8; Belongs to the AAA ATPase family. (406 aa) |
| | PSMD12 | 26S proteasome non-ATPase regulatory subunit 12. (456 aa) |
| | RYR2 | Ryanodine receptor 2. (4971 aa) |
| | RAC2 | Ras-related C3 botulinum toxin substrate 2. (197 aa) |
| | LOC112410961 | Cytochrome c oxidase subunit 5A, mitochondrial isoform X1. (199 aa) |
| | NCF4 | Neutrophil cytosol factor 4. (339 aa) |
| | PSMB7 | Proteasome subunit beta. (277 aa) |
| | ATP5PD | ATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (161 aa) |
| | GRIN1 | LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 1. (881 aa) |
| | NOXA1 | NADPH oxidase activator 1. (626 aa) |
| | C8G | Complement component C8 gamma chain; Belongs to the calycin superfamily. Lipocalin family. (255 aa) |
| | C5 | Complement C5. (1677 aa) |
| | NOTCH1 | LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 1. (2633 aa) |
| | PSMD4 | 26S proteasome non-ATPase regulatory subunit 4 isoform X1. (380 aa) |
| | HSPA5 | Endoplasmic reticulum chaperone BiP; Belongs to the heat shock protein 70 family. (655 aa) |
| | NDUFA8 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (172 aa) |
| | PSMA6 | Proteasome subunit alpha type. (246 aa) |
| | CREB3 | Cyclic AMP-responsive element-binding protein 3. (371 aa) |
| | PSMD7 | 26S proteasome non-ATPase regulatory subunit 7. (322 aa) |
| | LOC112411846 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa) |
| | LOC112411848 | Tubulin alpha-1D chain-like; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (307 aa) |
| | CACNA1B | Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (1986 aa) |
| | TUBB4B | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (373 aa) |
| | NDUFV2 | NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial isoform X1. (249 aa) |
| | PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (259 aa) |
