(10 nodes) DNA modification network (Streptococcus pneumoniae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	recD	Exonuclease V; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. (788 aa)
	hsdS	Type I restriction enzyme. (426 aa)
	hsdS-2	Type I restriction enzyme EcoKI specificity protein (S protein). (199 aa)
	xerD	Integrase/recombinase; Belongs to the 'phage' integrase family. (265 aa)
	hsdS-3	Type I site-specific deoxyribonuclease chain S. (522 aa)
	hsdM	EcoE type I restriction modification enzyme M subunit. (487 aa)
	hsdR	EcoA type I restriction-modification enzyme R subunit. (777 aa)
	hsdM-2	Type I restriction modification enzyme methylase subunit. (497 aa)
	hsdS-4	Type I restriction-modification enzyme 1, S subunit. (203 aa)
	hsdR-2	Type 1 restriction modification system endonuclease R. (1116 aa)

Your Current Organism:

Streptococcus pneumoniae

NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
hsdM	hsdR	spr0449	spr0450	EcoE type I restriction modification enzyme M subunit.	EcoA type I restriction-modification enzyme R subunit.	0.999
hsdM	hsdR-2	spr0449	spr0792	EcoE type I restriction modification enzyme M subunit.	Type 1 restriction modification system endonuclease R.	0.992
hsdM	hsdS	spr0449	spr0445	EcoE type I restriction modification enzyme M subunit.	Type I restriction enzyme.	0.998
hsdM	hsdS-2	spr0449	spr0446	EcoE type I restriction modification enzyme M subunit.	Type I restriction enzyme EcoKI specificity protein (S protein).	0.997
hsdM	hsdS-3	spr0449	spr0448	EcoE type I restriction modification enzyme M subunit.	Type I site-specific deoxyribonuclease chain S.	0.999
hsdM	hsdS-4	spr0449	spr0791	EcoE type I restriction modification enzyme M subunit.	Type I restriction-modification enzyme 1, S subunit.	0.993
hsdM	xerD	spr0449	spr0447	EcoE type I restriction modification enzyme M subunit.	Integrase/recombinase; Belongs to the 'phage' integrase family.	0.722
hsdM-2	hsdR	spr0790	spr0450	Type I restriction modification enzyme methylase subunit.	EcoA type I restriction-modification enzyme R subunit.	0.991
hsdM-2	hsdR-2	spr0790	spr0792	Type I restriction modification enzyme methylase subunit.	Type 1 restriction modification system endonuclease R.	0.998
hsdM-2	hsdS	spr0790	spr0445	Type I restriction modification enzyme methylase subunit.	Type I restriction enzyme.	0.994
hsdM-2	hsdS-2	spr0790	spr0446	Type I restriction modification enzyme methylase subunit.	Type I restriction enzyme EcoKI specificity protein (S protein).	0.992
hsdM-2	hsdS-3	spr0790	spr0448	Type I restriction modification enzyme methylase subunit.	Type I site-specific deoxyribonuclease chain S.	0.993
hsdM-2	hsdS-4	spr0790	spr0791	Type I restriction modification enzyme methylase subunit.	Type I restriction-modification enzyme 1, S subunit.	0.999
hsdR	hsdM	spr0450	spr0449	EcoA type I restriction-modification enzyme R subunit.	EcoE type I restriction modification enzyme M subunit.	0.999
hsdR	hsdM-2	spr0450	spr0790	EcoA type I restriction-modification enzyme R subunit.	Type I restriction modification enzyme methylase subunit.	0.991
hsdR	hsdS	spr0450	spr0445	EcoA type I restriction-modification enzyme R subunit.	Type I restriction enzyme.	0.995
hsdR	hsdS-2	spr0450	spr0446	EcoA type I restriction-modification enzyme R subunit.	Type I restriction enzyme EcoKI specificity protein (S protein).	0.992
hsdR	hsdS-3	spr0450	spr0448	EcoA type I restriction-modification enzyme R subunit.	Type I site-specific deoxyribonuclease chain S.	0.998
hsdR	hsdS-4	spr0450	spr0791	EcoA type I restriction-modification enzyme R subunit.	Type I restriction-modification enzyme 1, S subunit.	0.979
hsdR	xerD	spr0450	spr0447	EcoA type I restriction-modification enzyme R subunit.	Integrase/recombinase; Belongs to the 'phage' integrase family.	0.688

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