STRINGSTRING
ANF21780.1 ANF21780.1 ANF21781.1 ANF21781.1 ANF21782.1 ANF21782.1 purA purA ANF21787.1 ANF21787.1 ANF21800.1 ANF21800.1 ANF21802.1 ANF21802.1 ANF21806.1 ANF21806.1 ANF21807.1 ANF21807.1 ANF21814.1 ANF21814.1 ndk ndk ANF21832.1 ANF21832.1 A7C91_00400 A7C91_00400 pgk pgk ANF21869.1 ANF21869.1 thiI thiI A7C91_00640 A7C91_00640 pxpA pxpA ANF21910.1 ANF21910.1 ANF21912.1 ANF21912.1 ANF21918.1 ANF21918.1 ANF21925.1 ANF21925.1 ANF21930.1 ANF21930.1 ANF21944.1 ANF21944.1 ANF21966.1 ANF21966.1 ANF21969.1 ANF21969.1 ANF21970.1 ANF21970.1 ANF21975.1 ANF21975.1 ANF21980.1 ANF21980.1 ANF22012.1 ANF22012.1 ahcY ahcY ANF22027.1 ANF22027.1 tdk tdk A7C91_01680 A7C91_01680 ribL ribL queC queC pyrD pyrD ANF22081.1 ANF22081.1 ANF22084.1 ANF22084.1 ANF23572.1 ANF23572.1 pyrH pyrH A7C91_02010 A7C91_02010 ANF22098.1 ANF22098.1 ANF22112.1 ANF22112.1 ANF22117.1 ANF22117.1 ANF22118.1 ANF22118.1 ANF22128.1 ANF22128.1 ANF22134.1 ANF22134.1 speE speE ANF22139.1 ANF22139.1 ANF22150.1 ANF22150.1 ANF22151.1 ANF22151.1 A7C91_02425 A7C91_02425 ANF22168.1 ANF22168.1 ANF22171.1 ANF22171.1 ANF22182.1 ANF22182.1 ANF22185.1 ANF22185.1 ANF22191.1 ANF22191.1 ANF22193.1 ANF22193.1 prs prs moaA moaA ANF22210.1 ANF22210.1 ANF22220.1 ANF22220.1 pyrB pyrB pyrI pyrI ANF22236.1 ANF22236.1 ANF22237.1 ANF22237.1 ANF22239.1 ANF22239.1 ANF22240.1 ANF22240.1 A7C91_02895 A7C91_02895 ANF22244.1 ANF22244.1 ANF22258.1 ANF22258.1 ANF22270.1 ANF22270.1 ANF22283.1 ANF22283.1 ANF22287.1 ANF22287.1 ANF22300.1 ANF22300.1 nadE nadE pyrK pyrK atpD atpD atpB atpB atpA atpA atpF atpF atpC atpC atpE atpE ANF22320.1 ANF22320.1 ANF22321.1 ANF22321.1 ANF22322.1 ANF22322.1 speH speH ANF22336.1 ANF22336.1 mfnA mfnA sat sat cysC cysC A7C91_03560 A7C91_03560 ANF22358.1 ANF22358.1 ANF23585.1 ANF23585.1 ANF22373.1 ANF22373.1 ANF22391.1 ANF22391.1 mtaD mtaD mtnP mtnP tpiA tpiA ANF22417.1 ANF22417.1 ppnK ppnK ANF22435.1 ANF22435.1 ANF22439.1 ANF22439.1 eno eno deoC deoC ANF22448.1 ANF22448.1 mobA mobA ANF22483.1 ANF22483.1 ANF22485.1 ANF22485.1 ANF22486.1 ANF22486.1 ANF22487.1 ANF22487.1 ANF22507.1 ANF22507.1 ANF22525.1 ANF22525.1 ANF22527.1 ANF22527.1 ANF22537.1 ANF22537.1 pyrE pyrE ANF22556.1 ANF22556.1 ANF22562.1 ANF22562.1 fbp fbp gcvT gcvT ANF22569.1 ANF22569.1 ANF22577.1 ANF22577.1 ANF22579.1 ANF22579.1 porA porA porD porD ANF22582.1 ANF22582.1 porA-2 porA-2 vorD vorD ANF23595.1 ANF23595.1 ANF22594.1 ANF22594.1 ANF22596.1 ANF22596.1 A7C91_05000 A7C91_05000 glmM glmM A7C91_05115 A7C91_05115 ANF22625.1 ANF22625.1 ANF22642.1 ANF22642.1 ANF22643.1 ANF22643.1 guaB guaB ANF22655.1 ANF22655.1 nadA nadA ANF22659.1 ANF22659.1 pdxS pdxS pdxT pdxT purF purF purC purC purM purM purT purT purE purE purD purD ANF22679.1 ANF22679.1 purS purS purQ purQ purL purL purP purP guaAB guaAB guaAA guaAA ANF22701.1 ANF22701.1 ANF23598.1 ANF23598.1 ANF22714.1 ANF22714.1 ANF22770.1 ANF22770.1 ANF22792.1 ANF22792.1 ANF22794.1 ANF22794.1 adkA adkA cmk cmk ANF22863.1 ANF22863.1 A7C91_06585 A7C91_06585 ANF22880.1 ANF22880.1 mvk mvk ANF22883.1 ANF22883.1 fni fni ANF22887.1 ANF22887.1 trpB trpB ANF22904.1 ANF22904.1 ANF22905.1 ANF22905.1 ANF23603.1 ANF23603.1 rpiA rpiA upp upp ANF22915.1 ANF22915.1 ANF22927.1 ANF22927.1 ANF22934.1 ANF22934.1 ANF22935.1 ANF22935.1 mobA-2 mobA-2 ANF22957.1 ANF22957.1 ANF22966.1 ANF22966.1 ANF22970.1 ANF22970.1 ANF22983.1 ANF22983.1 gcvPB gcvPB gcvPA gcvPA glpK glpK tmk tmk pckG pckG gltX gltX ANF23038.1 ANF23038.1 ANF23050.1 ANF23050.1 ANF23059.1 ANF23059.1 ANF23060.1 ANF23060.1 ANF23070.1 ANF23070.1 pyrG pyrG ANF23080.1 ANF23080.1 ANF23088.1 ANF23088.1 ANF23105.1 ANF23105.1 tdh tdh ANF23115.1 ANF23115.1 gatE gatE gatD gatD thiL thiL ANF23139.1 ANF23139.1 ANF23148.1 ANF23148.1 thyX thyX ANF23151.1 ANF23151.1 apgM apgM ANF23154.1 ANF23154.1 ANF23162.1 ANF23162.1 queE queE hcp hcp ANF23194.1 ANF23194.1 ANF23195.1 ANF23195.1 ANF23615.1 ANF23615.1 ANF23196.1 ANF23196.1 ANF23616.1 ANF23616.1 ANF23198.1 ANF23198.1 ANF23210.1 ANF23210.1 ANF23211.1 ANF23211.1 ANF23214.1 ANF23214.1 ANF23216.1 ANF23216.1 A7C91_08750 A7C91_08750 ANF23250.1 ANF23250.1 ANF23252.1 ANF23252.1 ribK ribK mat mat ANF23264.1 ANF23264.1 ANF23271.1 ANF23271.1 metG metG ANF23278.1 ANF23278.1 ANF23279.1 ANF23279.1 ANF23280.1 ANF23280.1 ANF23281.1 ANF23281.1 ANF23282.1 ANF23282.1 ANF23283.1 ANF23283.1 ANF23284.1 ANF23284.1 surE surE ANF23303.1 ANF23303.1 thi4 thi4 thiC thiC purC-2 purC-2 ANF23306.1 ANF23306.1 purO purO ANF23324.1 ANF23324.1 gap gap ANF23348.1 ANF23348.1 ubiX ubiX ANF23352.1 ANF23352.1 A7C91_09410 A7C91_09410 ANF23374.1 ANF23374.1 cobD cobD cobS cobS ANF23380.1 ANF23380.1 cobQ cobQ ANF23385.1 ANF23385.1 ANF23386.1 ANF23386.1 ANF23387.1 ANF23387.1 ANF23630.1 ANF23630.1 ANF23631.1 ANF23631.1 moaC moaC panB panB ANF23634.1 ANF23634.1 mptA mptA glmS glmS adk adk ANF23470.1 ANF23470.1 ANF23483.1 ANF23483.1 ANF23484.1 ANF23484.1 cobB cobB glyA glyA thiI-2 thiI-2 ANF23533.1 ANF23533.1 ANF23534.1 ANF23534.1 ANF23548.1 ANF23548.1 hisG hisG hisD hisD ANF23551.1 ANF23551.1 hisH hisH hisA hisA hisF hisF hisI hisI hisC hisC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ANF21780.1biotin--[acetyl-CoA-carboxylase] ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (244 aa)
ANF21781.1Fructose-bisphosphate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)
ANF21782.1Pyruvate carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (583 aa)
purAHypothetical protein; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (339 aa)
ANF21787.1Nucleoside-diphosphate sugar epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (306 aa)
ANF21800.16-carboxy-5,6,7,8-tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (152 aa)
ANF21802.1Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (448 aa)
ANF21806.1NTPase; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. (175 aa)
ANF21807.1S-methyl-5-thioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. (356 aa)
ANF21814.1Acetylornithine deacetylase; Catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine; Derived by automated computational analysis using gene prediction method: Protein Homology. (350 aa)
ndkNucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (170 aa)
ANF21832.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (630 aa)
A7C91_00400Nodulation efficiency protein D-like protein (nefD); Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (420 aa)
pgkRestriction endonuclease; Frameshifted; internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (411 aa)
ANF21869.1acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa)
thiItRNA 4-thiouridine(8) synthase ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (380 aa)
A7C91_00640NAD(P)H-flavin oxidoreductase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (237 aa)
pxpALactam utilization protein LamB; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. (255 aa)
ANF21910.1methylmalonyl-CoA epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (134 aa)
ANF21912.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (144 aa)
ANF21918.1Asparagine synthase (glutamine-hydrolyzing); Derived by automated computational analysis using gene prediction method: Protein Homology. (484 aa)
ANF21925.1Molybdopterin molybdenumtransferase MoeA; Derived by automated computational analysis using gene prediction method: Protein Homology. (400 aa)
ANF21930.1Acetyl CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (462 aa)
ANF21944.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (562 aa)
ANF21966.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (122 aa)
ANF21969.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (204 aa)
ANF21970.1Nicotinamide-nucleotide adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (187 aa)
ANF21975.12-haloalkanoic acid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (236 aa)
ANF21980.1Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (207 aa)
ANF22012.1Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (189 aa)
ahcYAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (421 aa)
ANF22027.1Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (389 aa)
tdkThymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (192 aa)
A7C91_01680Hypothetical protein; Frameshifted; internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (382 aa)
ribLFAD synthase; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. (146 aa)
queC7-cyano-7-deazaguanine synthase QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (239 aa)
pyrDDihydroorotate dehydrogenase B catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. (300 aa)
ANF22081.1Sarcosine oxidase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (479 aa)
ANF22084.1Sarcosine oxidase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)
ANF23572.1KamA family radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (607 aa)
pyrHUMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (225 aa)
A7C91_02010Transporter; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (386 aa)
ANF22098.1D-nopaline dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (494 aa)
ANF22112.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (420 aa)
ANF22117.1hydroxymethylglutaryl-CoA synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. UPF0219 family. (350 aa)
ANF22118.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology. (386 aa)
ANF22128.1acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (459 aa)
ANF22134.1Amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
speESpermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine; Belongs to the spermidine/spermine synthase family. (283 aa)
ANF22139.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (135 aa)
ANF22150.1Glutamate synthase (NADPH), homotetrameric; Derived by automated computational analysis using gene prediction method: Protein Homology. (482 aa)
ANF22151.1ferredoxin-NADP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
A7C91_02425Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
ANF22168.1Glutamate synthase (NADPH), homotetrameric; Derived by automated computational analysis using gene prediction method: Protein Homology. (482 aa)
ANF22171.1Nicotinate phosphoribosyltransferase; Catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa)
ANF22182.1dCMP deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (179 aa)
ANF22185.1UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
ANF22191.1Biotin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (315 aa)
ANF22193.1Asparaginase; Derived by automated computational analysis using gene prediction method: Protein Homology. (306 aa)
prs16S ribosomal RNA; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (279 aa)
moaACyclic pyranopterin phosphate synthase; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. (308 aa)
ANF22210.1Glycine C-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)
ANF22220.1Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa)
pyrBAspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa)
pyrIAspartate carbamoyltransferase regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase. (151 aa)
ANF22236.1dTDP-4-dehydrorhamnose reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (287 aa)
ANF22237.1dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (185 aa)
ANF22239.1dTDP-glucose 4,6-dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)
ANF22240.1Glucose-1-phosphate thymidylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (352 aa)
A7C91_02895Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (331 aa)
ANF22244.1UDP-glucose 4-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa)
ANF22258.1Ribonucleoside-diphosphate reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (910 aa)
ANF22270.1Aldehyde ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (623 aa)
ANF22283.1Phosphoglucosamine mutase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphohexose mutase family. (455 aa)
ANF22287.1Catalyzes the transamination of diaminopimelate with 2-oxoglutarate to produce tetrahydrodipicolinate and glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology. (422 aa)
ANF22300.1Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (440 aa)
nadENAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (253 aa)
pyrKDihydroorotase; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). (233 aa)
atpDV-type ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane. (214 aa)
atpBATP synthase archaeal, B subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. (463 aa)
atpAATP synthase archaeal, A subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (585 aa)
atpFV-type ATP synthase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane. (102 aa)
atpCATP synthase A1 subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane. (368 aa)
atpEV-type ATP synthase subunit E; Produces ATP from ADP in the presence of a proton gradient across the membrane. (203 aa)
ANF22320.1V-type ATP synthase subunit K; Produces ATP from ADP in the presence of a proton gradient across the membrane; the K subunit is a nonenzymatic component which binds the dimeric form by interacting with the G and E subunits; Derived by automated computational analysis using gene prediction method: Protein Homology. (162 aa)
ANF22321.1V-type ATP synthase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the V-ATPase 116 kDa subunit family. (659 aa)
ANF22322.1ATP synthase archaeal subunit H; Derived by automated computational analysis using gene prediction method: Protein Homology. (103 aa)
speHS-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily. (141 aa)
ANF22336.1Phospholipase; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa)
mfnATyrosine decarboxylase MnfA; Catalyzes the decarboxylation of L-aspartate to produce beta- alanine; Belongs to the group II decarboxylase family. MfnA subfamily. (387 aa)
satSulfate adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sulfate adenylyltransferase family. (379 aa)
cysCAdenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. (180 aa)
A7C91_03560Permease; Incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
ANF22358.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa)
ANF23585.1Aminotransferase DegT; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DegT/DnrJ/EryC1 family. (367 aa)
ANF22373.1Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. (279 aa)
ANF22391.1CoA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (469 aa)
mtaDN-ethylammeline chlorohydrolase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. (424 aa)
mtnPMethylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (257 aa)
tpiATriose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (226 aa)
ANF22417.1Phosphopantetheine adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (160 aa)
ppnKNAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (278 aa)
ANF22435.1Molybdenum cofactor biosynthesis protein MoaE; Derived by automated computational analysis using gene prediction method: Protein Homology. (142 aa)
ANF22439.1Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (184 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (430 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (225 aa)
ANF22448.14-aminobutyrate aminotransferase; Catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (445 aa)
mobAMolybdenum cofactor guanylyltransferase MobA; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. (188 aa)
ANF22483.1Formate dehydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (711 aa)
ANF22485.1Coenzyme F420 hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (276 aa)
ANF22486.1Coenzyme F420 hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa)
ANF22487.1Coenzyme F420 hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (392 aa)
ANF22507.1Lipoate--protein ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
ANF22525.1Fuculose phosphate aldolase; Catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (186 aa)
ANF22527.1cob(I)yrinic acid a,c-diamide adenosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (175 aa)
ANF22537.1Pantothenate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (185 aa)
ANF22556.1Carbamate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbamate kinase family. (315 aa)
ANF22562.1Glyceraldehyde-3-phosphate:ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (653 aa)
fbpFructose 1,6-bisphosphatase; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (375 aa)
gcvTPermease; The glycine cleavage system catalyzes the degradation of glycine. (398 aa)
ANF22569.1Acylphosphatase; Catalyzes the hydrolysis of acylphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (91 aa)
ANF22577.1acetate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (646 aa)
ANF22579.1Pyruvate ferredoxin oxidoreductase; Catalyzes the formation of acetyl-CoA from pyruvate and coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (331 aa)
porAPyruvate ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (394 aa)
porDPyruvate ferredoxin oxidoreductase; Catalyzes the ferredoxin-dependent oxidative decarboxylation of pyruvate to form acetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (105 aa)
ANF22582.12-ketoisovalerate ferredoxin oxidoreductase; Catalyzes the coenzyme A-dependent oxidation of 3-methyl-2-oxobutanoate coupled to the reduction of ferredoxin producing S-(2-methylpropanoyl)-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
porA-2Pyruvate ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)
vorD2-ketoisovalerate ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (105 aa)
ANF23595.1Pyruvate ferredoxin oxidoreductase; Catalyzes the ferredoxin-dependent oxidative decarboxylation of pyruvate to form acetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (185 aa)
ANF22594.12-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (299 aa)
ANF22596.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (307 aa)
A7C91_05000tRNA-Ala; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (368 aa)
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (449 aa)
A7C91_05115Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (190 aa)
ANF22625.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (396 aa)
ANF22642.1Cobalt chelatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1254 aa)
ANF22643.1Magnesium chelatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (641 aa)
guaBIMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (486 aa)
ANF22655.1L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (465 aa)
nadAQuinolinate synthase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (302 aa)
ANF22659.1Nicotinate-nucleotide diphosphorylase (carboxylating); Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (277 aa)
pdxSPyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (335 aa)
pdxTGlutamine amidotransferase subunit PdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (197 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (443 aa)
purCPhosphoribosylaminoimidazolesuccinocarboxamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SAICAR synthetase family. (235 aa)
purMPhosphoribosylformylglycinamidine cyclo-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
purTPhosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (429 aa)
purE5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (143 aa)
purDPhosphoribosylamine--glycine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GARS family. (438 aa)
ANF22679.15-formaminoimidazole-4-carboxamide-1-(beta)-D- ribofuranosyl 5'-monophosphate synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (380 aa)
purSPhosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (80 aa)
purQPhosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (223 aa)
purLPhosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (713 aa)
purP5-formaminoimidazole-4-carboxamide-1-(beta)-D- ribofuranosyl 5'-monophosphate synthetase; Catalyzes the ATP- and formate-dependent formylation of 5- aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates. (331 aa)
guaABGMP synthase; Catalyzes the synthesis of GMP from XMP. (307 aa)
guaAAGMP synthase; Catalyzes the synthesis of GMP from XMP. (188 aa)
ANF22701.1Hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). (178 aa)
ANF23598.1Dolichol monophosphate mannose synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (352 aa)
ANF22714.1Acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (264 aa)
ANF22770.1Nicotinamidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (181 aa)
ANF22792.1Homoserine dehydrogenase; Catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)
ANF22794.1glutaconyl-CoA decarboxylase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (375 aa)
adkAAdenylate kinase; Catalyzes the formation of 2 ADP from AMP and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the archaeal adenylate kinase family. (196 aa)
cmkCytidylate kinase; Catalyzes the formation of (d)CDP from ATP and (d)CMP; Derived by automated computational analysis using gene prediction method: Protein Homology. (189 aa)
ANF22863.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (341 aa)
A7C91_06585Hypothetical protein; Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage. (267 aa)
ANF22880.1Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (278 aa)
mvkMevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (334 aa)
ANF22883.1Acetylglutamate kinase; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids. (258 aa)
fniType 2 isopentenyl-diphosphate Delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (377 aa)
ANF22887.1Serralysin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. (342 aa)
trpBTrpB-like pyridoxal-phosphate dependent enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (443 aa)
ANF22904.1Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (420 aa)
ANF22905.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (387 aa)
ANF23603.1Threonine synthase; Catalyzes the formation of L-threonine from O-phospho-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (444 aa)
rpiARibose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (227 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (222 aa)
ANF22915.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (783 aa)
ANF22927.1Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)
ANF22934.1Formate dehydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (687 aa)
ANF22935.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (165 aa)
mobA-2Molybdenum cofactor guanylyltransferase MobA; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. (193 aa)
ANF22957.1Formylmethanofuran dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa)
ANF22966.1Glucose-6-phosphate isomerase; Catalyzes the formation of D-fructose 6-phosphate from D-glucose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (189 aa)
ANF22970.1Phosphoglucosamine mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (455 aa)
ANF22983.1Alanine aminotransferase; Catalyzes the transamination of pyruvate or with glutamate; activity is seen with alanine, glutamate, and aspartate with either 2-oxoglutarate or pyruvate as the amino acceptor; Derived by automated computational analysis using gene prediction method: Protein Homology. (398 aa)
gcvPBGlycine dehydrogenase (aminomethyl-transferring); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (501 aa)
gcvPAGlycine dehydrogenase (aminomethyl-transferring); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (446 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. (493 aa)
tmkdTMP kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa)
pckGNDP-sugar synthase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. (624 aa)
gltXglutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (573 aa)
ANF23038.1Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (67 aa)
ANF23050.1acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa)
ANF23059.1Arginase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the arginase family. (241 aa)
ANF23060.1Fe-S cluster assembly protein HesB; Derived by automated computational analysis using gene prediction method: Protein Homology. (406 aa)
ANF23070.1Phosphoglycolate phosphatase, TA0175-type; Catalyzes the dephosphorylation of 2-phosphoglycolate. (236 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (532 aa)
ANF23080.1Glucose-1-phosphate thymidylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (419 aa)
ANF23088.1Adenylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (184 aa)
ANF23105.1Dihydropteroate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)
tdhL-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. (350 aa)
ANF23115.1hydroxymethylglutaryl-CoA reductase (NADPH); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HMG-CoA reductase family. (408 aa)
gatEglutamyl-tRNA(Gln) amidotransferase subunit E; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (626 aa)
gatDglutamyl-tRNA(Gln) amidotransferase subunit D; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (439 aa)
thiLThiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (311 aa)
ANF23139.1Agmatinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the arginase family. (287 aa)
ANF23148.1Ornithine carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (315 aa)
thyXHypothetical protein; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (245 aa)
ANF23151.1HIT family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (166 aa)
apgMPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (410 aa)
ANF23154.1Aldehyde ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (618 aa)
ANF23162.1Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (327 aa)
queE7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (253 aa)
hcpHydroxylamine reductase; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O. (446 aa)
ANF23194.1NADH-quinone oxidoreductase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology. (215 aa)
ANF23195.1NADH-quinone oxidoreductase subunit D; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the complex I 49 kDa subunit family. (391 aa)
ANF23615.1NADH-quinone oxidoreductase subunit C; Derived by automated computational analysis using gene prediction method: Protein Homology. (177 aa)
ANF23196.1NADH dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (190 aa)
ANF23616.1NADH dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (619 aa)
ANF23198.1NADH dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (495 aa)
ANF23210.1UDP-N-acetylglucosamine 2-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (377 aa)
ANF23211.1NDP-sugar dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (428 aa)
ANF23214.1Lipoate--protein ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (92 aa)
ANF23216.1Dihydrodipicolinate synthase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (293 aa)
A7C91_08750Formate transporter; Internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (680 aa)
ANF23250.1Formate dehydrogenase; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. (163 aa)
ANF23252.1Glutamate synthase; Unknown function; probable involvement in glutamate synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (352 aa)
ribKRiboflavin kinase; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. (212 aa)
matS-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family. (405 aa)
ANF23264.1Kinase; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily. (176 aa)
ANF23271.1Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (333 aa)
metGHypothetical protein; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (733 aa)
ANF23278.12-oxoglutarate ferredoxin oxidoreductase subunit gamma; Catalyzes the ferredoxin-dependent oxidative decarboxylation 2-oxoglutarate forming succinyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (186 aa)
ANF23279.12-oxoglutarate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)
ANF23280.12-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (382 aa)
ANF23281.12-oxoglutarate ferredoxin oxidoreductase subunit gamma; Catalyzes the ferredoxin-dependent oxidative decarboxylation of 2-oxoglutarate forming succinyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (170 aa)
ANF23282.12-oxoglutarate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
ANF23283.12-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa)
ANF23284.12-keto acid:ferredoxin oxidoreductase subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. (84 aa)
surE5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (260 aa)
ANF23303.1Bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (436 aa)
thi4Ribose 1,5-bisphosphate isomerase; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur. (252 aa)
thiCPhosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (414 aa)
purC-2Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SAICAR synthetase family. (219 aa)
ANF23306.15-formaminoimidazole-4-carboxamide-1-(beta)-D- ribofuranosyl 5'-monophosphate synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (310 aa)
purOIMP cyclohydrolase; Catalyzes the cyclization of 5-formylamidoimidazole-4- carboxamide ribonucleotide to IMP. (196 aa)
ANF23324.1ATP:cob(I)alamin adenosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (171 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
ANF23348.1NDP-sugar synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (413 aa)
ubiXAromatic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (177 aa)
ANF23352.1Adenylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (171 aa)
A7C91_09410MBL fold metallo-hydrolase; Frameshifted; internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (234 aa)
ANF23374.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (321 aa)
cobDCobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (293 aa)
cobSadenosylcobinamide-GDP ribazoletransferase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (231 aa)
ANF23380.1Cobalamin biosynthesis protein CobY; Derived by automated computational analysis using gene prediction method: Protein Homology. (179 aa)
cobQCobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (483 aa)
ANF23385.1Adenosylcobinamide amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (195 aa)
ANF23386.1Molybdenum cofactor biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (171 aa)
ANF23387.1Molybdopterin molybdenumtransferase MoeA; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa)
ANF23630.1Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (348 aa)
ANF23631.1Sugar dehydrogenase; Converts glucose to D-glucono-1,5 lactone; Derived by automated computational analysis using gene prediction method: Protein Homology. (259 aa)
moaCMolybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (155 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (282 aa)
ANF23634.1Aldehyde ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (619 aa)
mptAGTP cyclohydrolase; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. (268 aa)
glmSGlutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (602 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (224 aa)
ANF23470.1Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (479 aa)
ANF23483.1Phosphopantothenoylcysteine decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (403 aa)
ANF23484.1Aspartate racemase; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa)
cobBNAD-dependent protein deacylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sirtuin family. Class III subfamily. (251 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (427 aa)
thiI-2tRNA 4-thiouridine(8) synthase ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (363 aa)
ANF23533.12-oxoacid:ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (570 aa)
ANF23534.12-oxoacid ferredoxin oxidoreductase; Catalyzes the coenzyme A-dependent decarboxylation of 2-oxoacids, such as pyruvate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. (296 aa)
ANF23548.1ATP phosphoribosyltransferase regulatory subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (295 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (210 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (375 aa)
ANF23551.1Imidazoleglycerol-phosphate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (176 aa)
hisHImidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (195 aa)
hisA1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (229 aa)
hisFImidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (252 aa)
hisIBifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the PRA-CH family. (208 aa)
hisCHistidinol-phosphate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (335 aa)
Your Current Organism:
Thermococcus piezophilus
NCBI taxonomy Id: 1712654
Other names: ATCC TSD-33, T. piezophilus, Thermococcus piezophilus Dalmasso et al. 2017, Thermococcus sp. CDGS, UBOCC 3296, strain CDGS
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